Old deck Flashcards
<p>Tx of SIADH</p>
<p>fluid restriction</p>
<p>demeclocycline or vaptans (adh inhibitor)</p>
<p>Portal vein thrombosis tx</p>
<p>Control HMHG with variceal ligation</p>
<p>Anticoagulate once bleeding controlled</p>
<p>Consider distal spleno-renal shunt</p>
<p>MRSA tx</p>
<p>vancomycin</p>
<p>if vanc resistant then linezolid</p>
<p>VWF</p>
<p>binds GP1b on PLTs and attaches them to endothelium</p>
<p>Margin for invasives cancer vs. dcis</p>
<p>invasive cancer- gross negative</p>
<p>dcis- 1 to 2 mm</p>
<p>Interleukins 1, 2, 4</p>
<p>IL1: fever</p>
<p>IL2: T cell prolif and Ig production</p>
<p>IL4: T/B cell maturation</p>
<p>Ovarian tumor markers:</p>
<p>AFP</p>
<p>CEA</p>
<p>HCG</p>
<p>LDH</p>
<p>Ca 125</p>
<p>Inhibin</p>
<p>AFP: yolk sac tumor, endodermal sinus</p>
<p>CEA: mucinous ovarian tumor</p>
<p>HCG: ovarian choriocarcinoma, embryonal carcinoma</p>
<p>LDH: dysgerminoma</p>
<p>Ca 125: epithelial ovarian tumors</p>
<p>Inhibin: granulosa cell tumor</p>
<p>Hormones that increase LES pressure</p>
<p>Gastrin</p>
<p>Motilin</p>
<p>Origin of med thyroid cancer</p>
<p>4th pharyngeal arch NCC --> parafollicular C cells</p>
<p>Gardner syndrome</p>
<p>epidermal cysts, GI polyposis, osteomas</p>
<p>Indidcations for operative treatment of eso perf</p>
<ul> <li>early postemetic perforation</li> <li>hemodynamic instability</li> <li>intra-abdominal perforation</li> <li>extravasations of contrast into adjacent body cavities</li> <li>presence of underlying malignancy, obstruction or stricture</li></ul>
<p>place jejunostomy tube for feeding after. don't place gastric tube (conduit)</p>
<p>Uremic PLT dysfunction</p>
<p>2/2 renal disease</p>
<p>reversible dysfunction</p>
<p>tx- ddavp</p>
<p>B12 def</p>
<p>megalo anemia, neuropathy</p>
<p>Traction vs. Pulsion Diverticulum</p>
<p>traction- inflammation; all 3 layers; mid eso</p>
<p>pulsion- pressure; 2 layers; above circoph.</p>
<p>Positioning for indirect laryngoscopy</p>
<p>sitting upright with a straight back, leaning slightly toward you with chin pointing upward (“sniffing position”)</p>
<p>Kcal per macronutrient</p>
<p>protein = 4 kcal/g</p>
<p>dextrose = 3 kcal/g</p>
<p>lipid = 9kcal/g</p>
<p>carb = 4 kcal/g</p>
<p>p53</p>
<p>TSG on Ch17</p>
<p>cell cycle regulation and apoptosis</p>
<p>Rule of 9s</p>
<p>Each arm 9</p>
<p>Each leg 18</p>
<p>Ant belly 18, Post belly 18</p>
<p>Each hand 1</p>
<p>Ant face 4.5, Post face 4.5</p>
<p>Genitals 1</p>
<p>EBV associated with</p>
<p>B cell lymphome (Burkitt)</p>
<p>n/ph cancer</p>
<p>FRC</p>
<p>Volume of the lung after normal tidal expiration</p>
<p>Cisatracurium</p>
<p>non-depolarizing</p>
<p>cleared by Hoffman degradation</p>
<p>use in pts w/ renal and hepatic disease</p>
<p>tacro</p>
<p>MOA: calcineurin inhibitor (binds fK)</p>
<p>s/e- nephrotoxic, p. neuropathy, allopecia</p>
<p>SD</p>
<p>1, 2, and 3 SD = 67%, 95%, and 99.7% of the data</p>
<p>Intraductal papilloma</p>
<p>MCCO bloody nipple d/c</p>
<p>tx w/ duct excision</p>
<p>no increased r/o ca</p>
<p>Blood supply to esophagus</p>
<p>Upper 3rd- inferior thryoid artery</p>
<p>Middle 3rd- thoracic aorta</p>
<p>Lower 3rd- left gastric</p>
<p>Pleomorphic adenoma</p>
<p>MC benign H/N tumor</p>
<p>middle aged woman</p>
<p>slow growing; t2 bright</p>
<p>Tx: superficial parotidectomy even if asx</p>
<p>Rule of 6s</p>
<p>flow > 600/min</p>
<p>diameter > 6mm (after placement)</p>
<p>depth of 6mm</p>
<p>Comparing pressors</p>
<p>Norepi: alpha1 >alpha2,beta1</p>
<p>Epi: beta1, alpha1 > beta2, alpha2</p>
<p>Phenylephrine: alpha1 > alpha2(no beta)</p>
<p>MCCO of spontaneous bacterial peritonitis</p>
<p>E. Coli</p>
<p>Max dose of lido and bupiv</p>
<p>lido = 5mg/kg (7 w/ epi)</p>
<p>bupiv = 2.5 mg/kg</p>
<p>tx- lipid emulsion</p>
<p>Lamivudine</p>
<p>rTranscriptase inhibitor</p>
<p>Tx for hep B at low doses; HIV at high doses</p>
<p>Wound healing order of entry</p>
<p>plts → PMNs → macrophages → fibroblast → keratinocytes</p>
<p>5Ts of cyanosis</p>
<ol> <li>TOF</li> <li>Transposition of GVs</li> <li>Truncus art</li> <li>Tricuspid atresia</li> <li>TAPVC</li></ol>
<p>Pain after inguinal hernia repair</p>
<p>Ilioinguinal nerve</p>
<p>Injured at external ring. Lies anterior to cord</p>
<p>tx- local injection</p>
<p>Staging adrenal cancer</p>
<p>s1- <5cm</p>
<p>s2- >5cm</p>
<p>s3- n1 or t3</p>
<p>s4- mets</p>
<p>location of vagus nerve</p>
<p>LARPleft anterior, right posterior to esophagus</p>
<p>Dopamine dosing</p>
<p>low- d1/2 ago (renal dose)</p>
<p>medium- B ago</p>
<p>high- A ago</p>
<p>LIPID A</p>
<p>Gram negative bacteria (Klebsiella)</p>
<p>lipopolysaccharide layerendotoxin → septic shock</p>
<p><span>Beta lactamase inhibitors</span></p>
<p><span>Sulbactam/Tazobactam</span></p>
<p><span>Clavulanic acid</span></p>
<p></p>
<p>Contents of ant triangle</p>
<p>Carotid sheath, anca cervicalis, CN 12 (hypoglossal)</p>
<p>Contents of carotid sheath: CN10 (vagus), CCA, ICA, internal jugular</p>
<ul> <li>facial vein is the gateway</li></ul>
<p>BRCA risks</p>
<p>female breast, ovarian, male breast</p>
<p>I- 60, 40, 1</p>
<p>II- 60, 10, 10</p>
<p>Women withBRCAbreast CA have the same prognosis stage for stage as non-BRCAbreast CA</p>
<p>Kasabach-Merritt Syndrome:</p>
<p>hemangioma + thrombocytopenia</p>
<p>usually infants</p>
<p>resect!</p>
<p>Traumatic renal artery thrombosis</p>
<p>Unilateral- anticoagulation</p>
<p>Bilateral- OR or IR stent</p>
<p>Adenoid cystic carcinoma</p>
<p>MC minor salivary gland tumor (SM gland)</p>
<p>propensity for perineural invasion</p>
<p>Remains quiescent for years then metastasizes aggressively</p>
<p>SLNBx for melanoma</p>
<p>< .75 mm none</p>
<p>> .75 to 1 mm w/ ulceration, mitosis, invasion</p>
<p>Hernia repairs:</p>
<p>Bassini</p>
<p>McVay</p>
<p>Lichtenstein</p>
<p>Bassini: CT to IL</p>
<p>McVay: CT to cooper's</p>
<p>Lichtenstein: mesh</p>
<p>Casues of increased ETCO2</p>
<p>Increased muscle activity (shivering)</p>
<p>Increased metabolism (sepsis, fever, malignany hyperT)</p>
<p>Increased CO</p>
<p>Decreased minute ventilation</p>
<p>Acute cellular rejection</p>
<p>T cell mediated</p>
<p>path: portal cellular infiltrate + endotheliitis</p>
<p>tx: pulse steroids → consider thymo</p>
<p>Phyllodes tumor</p>
<p>“sarcoma of the breast”</p>
<p>tx- en bloc resection</p>
<p>hematog spread- chemo/LN dissection unnneccesary</p>
<p>Birads 0</p>
<p>More imaging: mammogram or targeted US</p>
<p>Mediastinal tumors</p>
<p>Anterior: lymphoma MC in children, thymoma MC in adults</p>
<p>Middle: lymphoma MC</p>
<p>Posterior: neurologic MC</p>
<p>Vitamin C</p>
<p>hydroxylation of lysine and proline</p>
<p>type 3 collagen cross-linking</p>
<p>Staph virulence factors</p>
<ol> <li>protein A: binds Fc component of IgG, forcing variable region to face away from bacterium</li> <li>Enterotoxins: intestines</li> <li>Toxic shock syndrome toxin-1 (TSST-1): superantigen. binds MHC II and T-cell receptor</li> <li>Coagulase: converts fibrinogen to fibrin clot</li> <li>Exfolatins: skin-exfoliating toxins</li></ol>
<p>CN11</p>
<p>spinal accessory nerve</p>
<p>exit jugulars foramen</p>
<p>innervates SCM and trapezius goes along post triangle</p>
<p>Tx of SVC syndrome</p>
<p>Angio stenting and steroidsfor sxatic relief</p>
<p>Urgent chemo/rads therapy</p>
<p>Silvadene, mafenide, silver nitrate s/e</p>
<p>Silvadene: s/e- neutropenia, hypersensitivity, kernicterus (avoid in preg)</p>
<p>Mafenide: psuedomonas coverages/e- met acidosis</p>
<p>Silver Nitrate: s/e- hypoNatremia</p>
<p>Indications for radioiodine thereapy</p>
<p>2-4 cm mass</p>
<p>vascular invasion</p>
<p>anti-Tg Ab</p>
<p>TG < 5</p>
<p>Hemophilia A</p>
<p>f8 DEFICIENCY SLR</p>
<p>MC inherited disorder</p>
<p>tx- DESMOPRESSIN (mild), f8 concentrate (severe)</p>
<p>Strongest layer of bowel</p>
<p>SM</p>
<p>Contents of post triangle</p>
<p>CN 11 subclavian artery</p>
<p>EJV</p>
<p>brachial plexus trunks</p>
<p>Paget-Schroetter syndrome</p>
<p>Exercise induced thrombosis of subclavian/axillary VEIN</p>
<p>Tx- catheter directed thrombolysis</p>
<p>NEC</p>
<p>Bloody stools after 1st feed</p>
<p>dx- pneumatosis</p>
<p>tx- resuscitation, abx; OR if free air, clinical deterioration</p>
<p>Fibroadenoma</p>
<p>cyclical pain</p>
<p>dx- US guided core bx</p>
<p>only excise if discordance with biopsy!</p>
<p>Pancuronium</p>
<p>non-depol</p>
<p>eliminated by kidney and liver</p>
<p>Location ofsuperior sympathetic block</p>
<ul> <li>3 to 5 cm in length</li> <li>on the longus capitus muscle</li> <li>anterior to the transverse process of the second, third, and rarely the fourth cervical vertebrae</li></ul>
<p>Order of contents in thoracic outlet</p>
<p>vein (SC)</p>
<p>phrenic</p>
<p>muscle (scalene)</p>
<p>artery (SC)</p>
<p>nerve (br plexus)</p>
<p>Insulinoma</p>
<p>Loc: throughout</p>
<p>Px: whipple's triad</p>
<p>tx- < 2cm encucleate, >2cm resect</p>
<p></p>
<p>GCS verbal</p>
<p>5- normal</p>
<p>4- confused</p>
<p>3- inappropriate words</p>
<p>2- incomprehensible</p>
<p>1- none</p>
<p><span>Plasmin</span></p>
<p><span>Degrades f5, 8, fibrinogen, and fibrin</span></p>
<p>TXA2</p>
<p>vasoconstrictors</p>
<p>released by PLTs</p>
<p>Pseudocyst</p>
<p>encapsulated</p>
<p>lack epithelial lining</p>
<p>>5cm requires drainage</p>
<p><span>Sevoflurane</span></p>
<p>fast, less laryngospasm, less pungent</p>
<p>good for mask induction</p>
<p><span>Fibrin</span></p>
<p><span>Links Gp2b/3a to form PLT plug</span></p>
<p>NOAC reversak</p>
<p>Dabigatran (pradaxa)- Idarucizumab, iHD</p>
<p>Apixaban- PCC (partial)</p>
<p>Rivoroxaban- PCC (partial)</p>
<p>Indications for post op radio-iodine</p>
<p>2-4 cm</p>
<p>vascular invasion</p>
<p>anti-Tg Ab</p>
<p>TG<5</p>
<p>PEAK and TROUGH</p>
<p>PEAK- amount</p>
<p>TROUGH- frequency</p>
<p>Desmoid tumor</p>
<p>Locally aggressive with no portential for mets</p>
<p>Tx with resection and chemo</p>
<p></p>
<p>MC vitamind def after REY GB</p>
<p>B12</p>
<p>Ulcers:</p>
<p>Marginal</p>
<p>Cameron</p>
<p>Marjolin ulcer</p>
<p>Cushing's ulcer</p>
<p>Marginal- REYGB at GJ anastomosis</p>
<p>Cameron- on lesser curve of large hiatal hernia</p>
<p>Marjolin ulcer- chronic wound</p>
<p>Cushing's ulcer- elevated ICP</p>
<p>Products of posterior pituitary</p>
<p>"PAO in the POST"</p>
<p>ADH, Oxytocin</p>
<p>2/2 direct stem from neurosecretory cell</p>
<p>Stage 3 breast cancer and tx</p>
<p>3a- 4 to 9 nodes --> consider neoadj for BCT</p>
<p>3b- chest wall (not pec wall) or breast skin --> neoadj required</p>
<p>3c- supra clavicular nodes --> neoadj required</p>
<p>Tx of GIST</p>
<p>Resection w/ gross margin</p>
<p>No LN dissection</p>
<p>Add imatinib (TK inhibitor) if >5m/50HPF</p>
<p>Non-cyanotic heart defects</p>
<p>ASD</p>
<p>VSD</p>
<p>coarctation</p>
<p>Bevacizumab</p>
<p>recombinant humanizedmonoclonal antibodythat blocks angiogenesis by inhibitingVEGF-A</p>
<p>c/i to BCT</p>
<p>multicentric</p>
<p>inflammatory ca</p>
<p>c/i to radiation</p>
<p><span>AT3 Functions</span></p>
<p><span>Inhibits thrombin2. Inhibits f9, 10, 11</span></p>
<p>Ranson's criteria on admission</p>
<p>"GA Law"</p>
<ol> <li>Glu > 200</li> <li>age > 55</li> <li>LDH > 350</li> <li>AST > 250</li> <li>WBC > 16</li></ol>
<p></p>
<p>Cholangiocarcinoma types</p>
<p>1- below confluence</p>
<p>2- at confluence</p>
<p>3- R or L hep duct</p>
<p>4- R and L hep duct</p>
<p>5- multicentric</p>
<p>Glycogen</p>
<p>stores depleted after 24-48h of starvation</p>
<p>MOST found in skeletal muscle, rest in the liver</p>
<p>Types of esophogectomy</p>
<p>Transhiatal- laparotomy and cervical incision/anast</p>
<p>Ivor Lewis- thoracic incisions/anast</p>
<p>type 3 choledochocal cyst</p>
<p>choledochocele</p>
<p>tx- transduodenal marsupialization or excision</p>
<p>Treatment of colo-cutaenous fistula</p>
<ul> <li>Start with conservative tx</li> <li>High output: > 500 cc/day --> likely OR</li> <li>Low Output: < 200 cc/dayt --> likely conservative</li> <li>OR if failed after about 6 weeks</li></ul>
<p>CPP</p>
<p>MAP - ICP</p>
<p>normal CPP > 60</p>
<p>Normal ICP < 20</p>
<p>hyperventilation to 35 decreases CO2 causing vascoconstriction and decreasing ICP</p>
<p>Accessible nodal stations w/ EBUS</p>
<p> 2, 3, 4, 7, 10, 11, 12</p>
<p>tx of Meckels</p>
<p>tx- resection if sxs.</p>
<ul> <li>if appendicits leave Meckel's alone</li> <li>If no appendicitis take out the Meckel's</li></ul>
<p>Only consider taking out incidentally found asx Meckel's in young/healthy pt</p>
<p>if bleeding, inflamed or tumor at base --> segmental resection</p>
<p>Hypocalcemia</p>
<p>tingling</p>
<p>chvostek/trousseau sign</p>
<p>EKG- qt prolongation</p>
<p>Angiodysplasia of the colon</p>
<p>2nd MC CO gi bleed (vs. div's)</p>
<p>Usually found in cecum and ascending colon</p>
<p><span>Effective for enteroccous</span></p>
<p>Ampicillin/Amoxacillin</p>
<p>Vancomycin</p>
<p>Timentin/Zosyn</p>
<p>(Resistant to all cephalosporins)</p>
<p>Lateral to medial femoral anatomy</p>
<p>Femoral nerve</p>
<p>Femoral artery</p>
<p>Femoral vein</p>
<p>Empty space (hernia)</p>
<p>Lacunar ligament</p>
<p>Superficial ring</p>
<p>Gastrin</p>
<p>G cells of antrum signal EC cells --> His --> Parietal cell --> HCl</p>
<p>Stimulated by ACh, beta ago, AA</p>
<p>Tx for gallstone ileus</p>
<p>Stable and healthy- stone removal and take down fistula</p>
<p>Unstable- stone removal only!</p>
<p>septic shock</p>
<p>high CI, low SVR, +/- wedge</p>
<p>Normal SBP in a neonate</p>
<p>60-90</p>
<p>How to reach D2 during EGD</p>
<p>right rotation and manipulate the up/down control knob</p>
<p>S/e of tamoxifen</p>
<p>dvt/pe</p>
<p>uterine cancer</p>
<p>Best test for resectability and staging of eso cancer</p>
<p>Resectability- ct</p>
<p>Staging- US</p>
<p>Specific to UC</p>
<p>Crypt abscess</p>
<p>Psuedopolyps</p>
<p>LeFort fxs</p>
<p>I- palate</p>
<p>II- nose and palate</p>
<p>III- entire face</p>
<p>Epoteitn</p>
<p>stimulated by HYPOXIA produced by kidney fibroblasts</p>
<p>Liver is major producer of EPO in fetus</p>
<p>Cutoff for low risk lung nodules not requiring follow-up</p>
<p>6mm</p>
<p>Best opioid to use for AKI</p>
<ul> <li>methadone and fentanyl/sufentanil</li> <li>hydromorphone or oxycodone are used with caution</li></ul>
<p>morphine and codeine are avoided</p>
<p><span>Anti-staph Penicillins</span></p>
<p>Oxacillin</p>
<p>Methicillin</p>
<p>Nafcillin</p>
<p>Bile concentration</p>
<p>Sodium chloride channels actively transport salt across the epithelium efficientlyand water follows passively in response to the resultant osmotic force</p>
<p></p>
<p>Warthin tumor/Papillary cystadenoma</p>
<p>benign tumor of salivary gland</p>
<p>often BILATERAL and 2/2 smoking</p>
<p>Tx- complete resection with uninvolved margins even if ASx</p>
<p>Hurthle cell</p>
<p>Usually benign</p>
<p>MUST do lobectomy to diagnose</p>
<p>tx- total thyroid if malignant. XRT effective.</p>
<p>Neostigmine</p>
<p>reversal of non-depol muscle relaxantsAChE inhibitor</p>
<p>Imaging associated with benign adrenal mass</p>
<p>< 10HU</p>
<p>Rapid washout</p>
<p>< 4cm</p>
<p>ITP</p>
<p>px- petechiae and megakaryotcytes</p>
<p>tx-steroids (IVIG 2nd line)</p>
<ul> <li>do not tx unless PLT < 30k or 20k in low risk</li></ul>
<p>Paired vs. unparied t test</p>
<p>Paired- compares study subjects at 2 different times (paired observations of the same subject)</p>
<p>Unparied-compares two different subjects</p>
<p>Respiratory quotient</p>
<p>CO2 produced / O2 consumed</p>
<p>>1 → carb is major nutrient</p>
<p>.7 → lipids major nutrient</p>
<p>Absolute c/i to spinal anesthesia</p>
<p>Infection at the site</p>
<p>Hypovolemia</p>
<p>Allergy</p>
<p>Increased ICP</p>
<p>Parkland formula</p>
<p>4 x weight x TBSA 1st 1/2 in 1st 8h</p>
<p>2nd half next 16</p>
<p>Steps of rapid sequence intubation</p>
<p>c-spine stabilize → preO2 → fentanyl → etomidate → succinylcholine</p>
<p>Where to find superior and inferior PD during a whipple</p>
<p>Superior:pancreatic head</p>
<p>Inferior: uncinate process</p>
<p>Tx of Barrett's</p>
<p>low grade dysplasia: repeat scope/bx in 6m</p>
<p>high grade dysplasia: endoscopic mucosal resection</p>
<p>cyclosporine</p>
<p>MOA: calcineurin inhibitor</p>
<p>s/e- 100x less potent then tacro, nephrotoxic, hypertrichosis, gum hyperplasia</p>
<p>Effective for VRE</p>
<p>Synercid</p>
<p>Linezolid</p>
<p>Kaposi's sarcoma</p>
<p>HSV8</p>
<p>Violet/brown papules</p>
<p>T and N staging eso cancer</p>
<ul> <li>t1a- LP and MM</li> <li>t1b- SM</li> <li>t2- MP</li> <li>t3- adventitia</li> <li>t4a- resectable structures</li> <li>t4b- unresectable structures</li></ul>
<p>n1: 1-2 nodes</p>
<p>n2: 3-6 nodes</p>
<p>n3: 7+</p>
<p>CRC T and N</p>
<p>t1- SM</p>
<p>t2- MP</p>
<p>t3- xMP/subserosa</p>
<p>t4- invade</p>
<p>n1- 1-3, n2- >=4</p>
<p>Triple therapy</p>
<p>PP1 + 2 antibioticsabxs: amoxicillin, metronidazole, tetracycline, clarithromycin</p>
<p>Chole docho in REY bypass pt</p>
<p>w/ GB --> lap chole with CBD exploration --> ERCP through remnantstomach</p>
<p>w/out GB --> ERCP with double balloon endoscopt --> ERCP throught remnant stomach</p>
<p>bile salt circulation</p>
<ol> <li>conjugate in hepatocytes into gly/taurine</li> <li>secreted into bile</li> <li>80% reabsorbed in ileuim ACTIVELY</li> <li>20% DECONJUGATED by bacteria</li> <li>deconjugated salts absorbed in colon PASSIVELY</li> <li>6. 5% is excreted</li></ol>
<p>Howship-Romburg Sign</p>
<p>Pain in medial thigh with internal rotation and extension</p>
<p>Suggests an obtruator hernia</p>
<p>MS vs. ED</p>
<p>MS- Fibrillin defect (elastin); AD, tall, aortic root dilation, lens defect, arachnodactyly</p>
<p>ED- t1, t3 , t5 collagen defect; hyper elastic skin, hypermobile joints</p>
<p>Most abundant bacteria in the colon</p>
<p>Bacteroides fragiles</p>
<p>Liver lesions on arterial phase:</p>
<ul> <li>HCC</li> <li>Mets</li> <li>Adenoma</li> <li>Hemangioma</li> <li>FNH</li></ul>
<ul> <li>HCC- Homogeneous enhancement</li> <li>Mets- Hypoattenuation</li> <li>Adenoma- Heterogeneous enhancement</li> <li>Hemangioma- Periph enhancing</li> <li>FNH- Centrifugal enhancing</li></ul>
<p>Number of lung segments</p>
<p>R-10</p>
<p>L-8</p>
<p>confounding</p>
<p>a variable that influences both thedependent variable and independent variablecausing a spurious association</p>
<p>Epidural hematoma</p>
<p>Biconvex</p>
<p>MMA</p>
<p>DOES NOT suture lines</p>
<p>Bethesda criteria for thyroid</p>
<p>10 mm is cutoff to get an FNA</p>
<ol> <li>Non-diagnostic → repeat FNA</li> <li>Benign → follow-up</li> <li>Undetermined significance → repeat FNA</li> <li>Suspicious for follicular neoplasm → lobectomy, repeat FNA, or genetic testing (no core needle)</li> <li>Suspicious for malignancy → lobectomy vs. thyroidectomy</li> <li>Malignant → thyroidectomy</li></ol>
<p><span>Effective for P/A/S</span></p>
<p>Ticarcillin (+ticarcillin), Piperacillin (+Zosyn)</p>
<p>3/4G cephalosporin (ceftriaxone, cefepime)</p>
<p>Aminoglycodies (genta, tobra)</p>
<p>Flouroquinolones</p>
<p>Meropenem/Imipenem</p>
<p></p>
<p>HNPCC and criteria</p>
<p>HNPCC pts who fulfill Amsterdam clinical criteria for Lynch syndrome</p>
<p>Criteria:</p>
<ul> <li>3 relatives (one 1st deg)w/ Lynch syndrome-associated cancer (CRC, endometrial, small bowel, ureter/renal)</li> <li>2 successive generations</li> <li>1 < 50 yo</li></ul>
<p>MALT lymphoma</p>
<p>associated w/ h. Pylori.</p>
<p>Tx:</p>
<ul> <li>Low grade: triple therapy</li> <li>High grade: chemo and XRT (CHOP) +/- rituximab</li></ul>
<p>MCCO chylous ascites</p>
<p>malignancy</p>
<p>Gastroschisis</p>
<p>GastRoschisis to the Right of midline</p>
<p>rare defects...EXCEPTION- instestinal atResia</p>
<p>Tx of AT3 def</p>
<p>Heparin does not work!</p>
<p>Tx- recombinant at3 or FFP followed by heparin then warfarin</p>
<p>Indications to tx ICA stenosis</p>
<p>if Asx, only tx if > 60</p>
<p>if sx, tx if > 50</p>
<p>sxs- contralateral motor/sensory sxs, ipsi vision sxs</p>
<p>STSG vs. FTSG</p>
<p>STSG- epi + part dermis; worse cosmesis; more contracture! (don't use over joints)</p>
<p>FTSG- epi + dermis; lower survival; more resistant; hypertrophic scar formation; more sensation</p>
<p>ASA</p>
<p>irreversible inhibitor of PG metabolism in PLTs</p>
<p>2/2 cox acetylation</p>
<p>7-days of PLT dysfunction</p>
<p>Tx for beta blocker overdose</p>
<p>glucagon</p>
<p>Products of anterior pituitary</p>
<p>TSH, ACTH, FSH/LH, GH, Pro</p>
<p>neurosecretory cell stimulates hypothalamus which lets go of releasing hormone</p>
<p>Rapid coumadin reversal</p>
<p>PCC</p>
<p>Pyoderma gangrenosum</p>
<p>associated w/ IBD</p>
<p>RESOLVES after resection</p>
<p>pre-tibial</p>
<p>tx- steroids</p>
<p>Central cord syndrome</p>
<p>loss of pain, temp, motor</p>
<p>motor UE> LE loss (vs. anterior syndrome)</p>
<p>Scope schedule after Crohn's dx</p>
<p>10 years after dx then every year to r/o dysplasia</p>
<p>TNFa</p>
<p>produced by macrophages</p>
<p>causes cachexia</p>
<p>Beckwith Wiedmann Syndrome</p>
<p>3m-2yAssociated with hepatoblastoma and wilm's tumor</p>
<p>type 1 choledochocal cyst</p>
<p>fusiform dilationtx- excision w/ REY H-J</p>
<p><span>Cryo</span></p>
<p><span>vWF, f8, fibrinogen</span></p>
<p>Breslow depth</p>
<p>t1: < 1mm → .5-1 cm margin</p>
<p>t2: 1-2 mm → 1-2 cm margin</p>
<p>t3: > 2 mm → 2 cm margin</p>
<p>Best test to dx gastroparesis</p>
<p>Scintigraphic gastric emptying</p>
<p>Atlanta classification pancreatits</p>
<p>1. Interstitial:</p>
<ul> <li><4w- acute peripanc collection,</li> <li>>4w psuedocys</li></ul>
<p>t2. Necrotic:</p>
<ul> <li><4w- acute necrotic collection</li> <li>>4w- walled of necrosis</li></ul>
<p><span>FFP</span></p>
<p><span>All factors, Protein C and S, AT3</span></p>
<p>Child's Pugh Score</p>
<p>Billirubin, Albumin, INR, Ascites, Encephalopathy</p>
<p>ARDS ratio</p>
<p>P/F</p>
<ul> <li>mild- 200 to 300</li> <li>moderate 100-200</li> <li>severe < 100</li></ul>
<p>Orientation of portal triad</p>
<p>Bile duct lateral</p>
<p>Hepatic artery medial</p>
<p>Portal vein posterior</p>
<p>Schiatzki's Ring</p>
<p>Associated with hiatal hernia</p>
<p>Tx- only if sxatic. dilation and PPI; do not resect</p>
<p>MOA reglan and erythromcyin</p>
<p>reglan: dopamine antagonist</p>
<p>erythromycin: motlin receptor agonist causing SM contraction</p>
<p>indications to bx a neck mass</p>
<p>confirm FNA or core needle with excisional biopsy!</p>
<ul> <li>>1.5 cm</li> <li>enlarged node withoutsigns of infection</li> <li>persistence after trial of antibiotics and observation >2-4 wks</li> <li>increasing size of mass</li></ul>
<p>Peri-op anti-PLT agents</p>
<p>Clopidogrel (plavix): hold 5-7 days before elective surgery</p>
<p>ASA: continue through the surgery</p>
<p>neurogenic shock</p>
<p>high CI, low SVR, low wedge</p>
<p>Indications for iHD</p>
<p>GFR 10-15 for sxatic</p>
<p>GFR < 5 for asymptomatic</p>
<p>Sxs = AEIOU (acid, lytes, intox, olverload, uremia)</p>
<p>Breast Cancer in pregnancy</p>
<p>1T- MRM. Chemo is not OK.</p>
<p>2T/3T- consider BCT. Modfied radio-isotope. Chemo is OK. Post delivery radiation.</p>
<p>Who needs stress dose steroids</p>
<p>>20 mg of steroids for > 3 weeks</p>
<p>Frey syndrome</p>
<p>gustatory sweating s/p parotidectomy</p>
<p>Layers of colon/rectum</p>
<p>1. mucosa</p>
<p>2. sub-mucosa</p>
<p>3. muscularis propria</p>
<p>4. serosa</p>
<p>FNH</p>
<p>path- CENTRAL STELLATE SCAR!; bright on arterial phase homogenous</p>
<p>tx- resect if sxatic. no malignant potential.</p>
<p>TOF</p>
<p>Most common cyanotic defect</p>
<p>VSD, PS, OA, RVH</p>
<p>tx- beta blocker; surgery at 3-6m</p>
<p>Omphalocele</p>
<p>2/2 failure of umbo ring closure 11th week gut returns to abdominal cavity</p>
<p>normal bowel (protected)</p>
<p>Other congenital defect are more common</p>
<p>Hard signs of vascular injury</p>
<p>shock</p>
<p>expanding hematoma</p>
<p>pulsatile bleed</p>
<p>thrill/bruit</p>
<p>absent pulse</p>
<p>ischemia</p>
<p>Primary lymphoid organ vs. secondary</p>
<p>Primary: generate cells i.e. liver, bone, thymus</p>
<p>Secondary: maintain cells i.e. nodes, spleen, MALT</p>