OL-LEC-1 INTRO Flashcards
Study of worms
Helmintology
Study of protozoans
Protozology
Stage of parasite to identify accurately what parasite is present on the sample
Diagnostic Stage
What are the 4 STH?
Ascaris lumbricoides
Ancylostoma duodenale & Necator americanus
Trichuris trichiura
Strongyloides stercoralis
Percentage of hookworm in this country between the two hookworms
Necator americanus: 70%
Ancylostoma duodenale: 30%
Egg that is still in the uterus of the female species
ovum
2 forms of larvae stage specifically of nematodes
Flariform larvae
Rhabditiform larvae
the infective stage; long, thread-like; often “designed” for penetration
Filariform larvae
characterized by the presence of a muscular
esophagus and bulbular pharynx. The first “molt “ worms after leaving the egg are termed “________”
Rhabditiform larvae
Staging of the developmental process of helminths
- Egg/ovum
- Larvae
- Adult
Developmental stages of protozoans
- Cysts
- Tropozhoite
Resistance stage of the protozoan
Cysts
Vegetative or parasitic stage of protozoan
Trophozoite
Largest intestinal amoeba
Entamoeba coli cysts
The only pathogenic intestinal amoeba
Entamoeba histolytica
The only known ciliate to cause human infection
Balantidium coli
Examples of commensal protozoans
Endolimax nana
Chilomastix mesneli (mesnili on net?)
Features of the parasite that can be observed by the eyes
morphology
What is the magnitude of the diseases
epidemiology
What are the diseases it cause
pathogenecity
What procedures do we do in order to determine the presence or absence of the parasite
laboratory diagnosis
Where we can commonly find the parasite
distribution and life cycles
where is filariasis more commonly found in the Philippines?
southern Philippines (mindanao)
Difference of control and preventation
control- mitigate the effect
prevention- prevent the disease to ever happen
The area of biology concerned with the phenomenon of dependence of one living organism on another
Parasitology
Deals with parasites which infect man, the diseases they produce, the response generated by him against them and various methods of diagnosis and prevention
Clinical Parasitology
An organism that is entirely dependent on another organism for all part of its life cycle and metabolic requirements
Parasiteq
The organism which a parasite relies on
host
small, unicellular and multiplies within vertebrate host (type of parasite)
Microparasites
Examples of microparasites
bacteria, protozoans, viruses
large, multicellular, no direct reproduction within its vertebrate host (type of parasite)
Macroparasites
Example of macroparasites
helminths
A non living parasite that only becomes living when it penetrates a living host
Virus
Types of helminths
Roundworms (Nematodes)
Flukes (Trematodes)
Tapeworms (Cestodes)
Thorny-headed worms (Acanthocephala)
Type of helminth that only affects animals, rarely humans
Thorny-headed worms (Acanthocephala)
Classification of parasites according to location (habitat)
Ectoparasites and Endoparasites`
lives on the surface of the skin/ temporarily invade superficial tissues of the host
Ectoparasites
Ectoparasites causes?
Infestation
Live within the body of the host
Endoparasites
Endoparasites causes?
Infection
Parasite that infects are called?
Endoparasites
Parasites that infest are called?
Ectoparasite
All protozoans and helminths are what type of parasite according to habitat?
Endoparasites
Organisms that cannot exist without a host
Obligate parasite
Organisms that under favorable circumstances may live either parasitic or free-living existence
Facultative parasite
Organisms that attack an unusual host
Accidental parasites
organisms that attack a host where they cannot live or develop further
Aberrant parasites
Non-parasitic stages of existence which are lived independently of a host
Free-living
Examples of ectoparasites
Lice
Ticks
Mites
Flea
Scientific name head lice
Pediculus humanus capitis
Scientific name body lice
Pediculus humanus corporis
Flea scientific name
Siphonaptera spp.
Examples of Siphonaptera
Xenopsylla cheopis (oriental rat flea)
Xenopsylla cheopis causes what disease?
Bubonic plague
Ticks scientific name
Ixodes spp.
Examples of obligate parasites
Toxoplasma gondii
Example of facultative parasites
Naegleria fowleri
Acanthamoeba
Naegleria fowleri causes?
PAM - Primary amebic meningoencephalitis
Acanthamoeba enters in what part of the body?
Periorbital/ orbital region
Naegleria fowleri enters on what part of the body?
Nasal cavity
Example of accidental parasite
Echinococcus granulosus
Echinococcus granulosus main hosts
Dog- definitive
Sheep - intermediate
Aberrant parasites examples
Toxocara canis
Toxocara cati
Classification of mites
Mesostigmata
Prostigmata
Astigmata
Respiratory opening of mites
stigmata
Differentiate mesostigmata, prostigmata, astigmata
Mesostigmata: Stigmata between 3rd and 4th coxa (legs) found in both sides and also has a peritreme
Prostigmata: Stigmata between ears
Astigmata: No stigmata
vector borne diseases examples
Filariasis
Malaria
Dengue
Chikungunya
Zika
Yellow fever
Examples of mosquito species
Anopheles spp.
Aedes spp.
Culex spp.
Mansonia spp.
Arboviral diseases
Dengue
Chikungunya
Zika
Yellow fever
Arboviral diseases causing mosquito
Aedes aegypti
Wuchereria bancrofti mosquito (filariasis)
Culex
Brugia malayi mosquito (filariasis)
Mansonia
Malaria mosquito (plasmodium species)
Anopheles spp.
Ticks stigmata are found in?
Metastigmata (meaning they have complex breathing apparatus, these are known as spiracles and are located on either side of the idiosoma)
soft ticks
Argasidae
hard ticks
Ixodidae
Classification of parasites according to disease spectrum
acute, chronic, commensal, opportunistic
Examples of acute disease causing parasites
Plasmodium spp.
Trypanosoma spp.
Entamoeba histolytica
Examples of chronic disease causing parasites
Toxoplasma gondii
Plasmodium spp.
Echinococcus granulosus
Schistosoma spp.
Taenia solium
Examples of commensal parasites
Entamoeba gingivalis
are organisms that typically do not cause disease in healthy individuals but can cause infections or diseases when the host’s immune system is compromised or when other predisposing factors are present.
opportunistic parasites
Examples of commensal parasites
Pneumocystis jirovecii
Toxoplasma gondii
Cryptosporidium spp.
Candida species
Strongyloides stercoralis
Examples of blood residing parasites
Plasmodium spp.
Leishmania
Trypanosoma
Babesia
Plasmodium targets what part of the blood and causes what?
Red blood cells - Malaria
Leishmania targets what part of the blood and causes what?
WBC specifically macrophage/ monocyte - Visceral leishmaniasis (VL), also known as kala-azar
Trypanosoma causes what disease and what is its vector
African Trypanosomiasis, also known as “sleeping sickness”
Tsetse fly
Babesia targets what cell and causes what disease?
RBC - Babesiosis
Eye parasites
Loa loa
Onchocerca volvulus
Mansonella perstans - (not really, ugandan eye worm ang name pero very rare na it affects the eyes, ang main target is connective tissue)
Lymphatic parasites
Brugia spp.
Wuchereria bancrofti
Calssification of parasites according to mode of transmission
fecal-oral
skin penetration
soil transmitted
where sexual reproduction of the parasite takes place or in which the most highly developed formed of the parasite occurs
Definitive host
When the most mature form of the parasite is not obvious, what will we consider as the definitive host?
Mammalian host
Where the larval or asexual stages of a parasite is found
Intermediate host
Where the larval stage of a parasite survives but does not develop further
Paratenic host
Harbors the parasite and serves as an important source of infection to other susceptible hosts
Reservoir host
Important to notice in the control of parasitic diseases in epidemiology
Reservoir host
Plasmodium knowlesi reservoir host
Macaque monkeys
Parasites with 1 intermediate host
Flea (Siphonaptera):
Dipylidium caninum
Hymenolepis diminuta
Parasites with no intermediate hosts
Protozoans:
Entamoeba histolytica
Giardia lambia
Chilomastix mesnili
Balantidium coli
Trichomonas vaginalis
Helminths:
Enterobius vermicularis
Hymenolepis nana
STHs (Ascaris, Trichuris, Hookworms)
Parasites with 1 intermediate host
Man:
Echinococcus granulosus
Plasmodium spp.
Triatoma genus (Triatomine bugs)
Rhodnius
Triatoma
Panstrongylus
Parasites with 1 intermediate host
Pig:
Taenia solium
Trichenella spiralis
Parasites with 1 intermediate host
Cattle:
T. saginata
Parasites with 1 intermediate host
Triatoma/ Reduviid/ Assasin bug:
Tryponosoma cruzi
Parasites with 1 intermediate host
Mosquito (Aedes, Anopheles, Mansonia)
Brugia Malayi
Parasites with 1 intermediate host
Mosquito (Aedes, Anopheles in rural areas;
Culex quinquefasciatus in urban areas)
Wuchureria bancrofti
Parasites with 1 intermediate host
Snail
Schistosoma spp.
Parasites with 1 intermediate host
Copepod/ water fleas
Dracunculus medinensis
Parasites with 1 intermediate host
Sandfly: Lutzomyia, Phlebotomus spp.
Leishmania
Parasites with 1 intermediate host
Tsetse fly: glossina spp.
Trypanosoma spp.
Parasites with 1 intermediate host
Chrysops/ Deer fly/ Mango fly/ Tabanid fly: C. dimidiate C. silocea
Loa loa
Parasites with 1 intermediate host
Simulium/ Black fly
Onchocerca volvulus
Parasites with 2 intermediate hosts
snail, fish
Clonorchis sinensis
Parasites with 2 intermediate hosts
Cyclops, fish
Diphyllobotrium latum
Parasites with 2 intermediate hosts
Snail, plant
Fasciola spp.
Parasites with 2 intermediate hosts
Snail, freshwater crustaceans
Paragonimus westermani
Only Schistosoma found in the Philippines
Schistosoma japonicum
Schistosoma japonicum intermediate host
Oncomelania spp.
Schistosoma japonicum intermediate host
MOST COMMON IN THE PHILIPPINES
Oncomelania quadrasi variety hepensis
Oncomelania hupensis quadrasi -net
Schistosoma mansoni host
Biomphalaria spp.
Schistosoma haematobium
Bulinus spp
Common house fly common name
Musca domestica
Insect bite method of transmission
Inoculation
Two species of tsetse fly
Glossina palpalis
Glossina morsitans
Other term for definitive host
Final host
Other term for intermediate host
Secondary host
Two types of intermediate host
Primary and Secondary INTERMEDIATE host
(label it kasi primary and secondary can be used as other terms of definitive and intermediate host)
An animal infection that is naturally transmissible to humans either directly or indirectly via a vector
Zoonosis
Zoonotic source and disease of Trypanosoma cruzi
Triatoma bug
American trypanosomiasis/ Chaga’s disease
Zoonotic source and disease of Crytosporidium parvum
Animals
Cryptosporidiosis
Zoonotic source and disease of
Fasciola hepatica and gigantica
Snail, plants
Fascioliasis
Zoonotic source and disease of
Echinococcus granulosus
Dog
Hydatid Disease
Zoonotic source and disease of
Leishmania spp.
Sand fly
Leishmaniasis
Zoonotic source and disease of
Schistosoma
haematobium
japonicum
mansoni
Fresh water snail
Bulinus spp
Oncomelania spp
Biomphalaria spp
schistosomiasis
Zoonotic source and disease of
Trichinella spiralis
Bears, pigs, rats
Trichinosis
Agent that transmits infection from human host to another
Vector
Assists in the transfer of parasitic forms between host but is not essential in the life cycle
Mechanical vector
Mechanical vector of Ascaris lumbricoides
Periplaneta americana (american cockroach)
Mechanical vector of Entamoeba histolytica
Musca domestica (common housefly)
Disease caused by Musca domestica by Entamoeba histolytica
Amoebic dysentery (amebiasis)
Differentiate male and female mosquito
Male antennae are bushy
Distinct characterization of Anopheles spp.
proboscis is same length with pulps
Differentiate male and female flies
males have darker last two abdomens
both host and parasite are dependent with each other
Symbiosis
Only the parasite derives benefit without causing an injury to the host
Commensalism
The parasite benefits and the host suffers
Parasitism
Sources of parasitic infection (TABLE)
modes of transmission or routes of transmission - sir
Contaminated soil (with human excrements)
Contaminated water (with human excrements)
Freshwater fishes
Freshwater crabs, crayfishes, and other crustaceans
Raw undercooked pork and beef
Freshwater aquatic plants (watercress)
Bloodsucking insects
Housefly
Dogs
Cat
Man
Auto infection
Soil transmitted helminths
Ascaris lumbricoides
Hookworms
Trichuris trichiura
Strongyloides sterocoralis
Contaminated water examples of source of parasite
Intestinal protozoans
Balantidium coli
Entamoeba histolytica
Giardia lamblia
Contaminated water examples of source of parasite
Cestodes
Hymenolepis nana
Taenia solium
Contaminated water examples of source of parasite
Trematodes
Schistosoma spp.
Freshwater fishes examples of source of parasite
Diphyllobothrium latum
Clonorchis sinensis
Opisthorchis viverrini
Opisthorchis felineus
Caused by S. haematobium by entering the genital areas of females by merely coming in contact with infested waters
genitourinary schistosomiasis
Freshwater crabs, crayfishes, and other crustaceans examples of source of parasite
Paragonimus westermani
Raw uncooked pork examples of source of parasite
Sarcocystis suihominis
Trichinella spiralis
Taenia solium
Raw uncooked beef examples of source of parasite
Sarcocystis hominis
Taenia saginata
Toxoplasma gondii
Freshwater aquatic plants examples of source of parasite
Fasciola hepatica
Fasciola gigantica
Bloodsucking insects examples of source of parasite
Blood protozoans: Plasmodium spp. Babesia spp.
Filarial worms:
Lymphatic = Wuchereria and Brugia
Non Lymphatic = Mansonella spp. Onchocerca volvulus
Non Filarial worms:
Dirofilaria spp.
Blood flagellates:
Leishmania spp. Trypanosoma cruzi, brucei
Housefly examples of source of parasite
Entamoeba histolytica
Dog examples of source of parasite
Echinococcus granulosus
Toxocara canis
Cat examples of source of parasite
Toxocara cati
Man examples of source of parasite
Entamoeba histolytica
Enterobius vermicularis
Hymenolepis nana
Autoinfection examples of source of parasite
Enterobius vermicularis
Strongyloides stercoralis
You infected your ownself
Autoinfection
Unordinary mode of transmission
Retroinfection
Sources of parasitic infection
Blood-borne/ Organ Transplantation
Food-borne
Laboratory-acquired
Soil-transmitted
Vector-borne
Modes of transmission
Ingestion/ Fecal-oral route
Skin
Sexual contact
Kissing/ sharing contaminated drinking utensils
Congenital
Inhalation
Latrogenic (transfusion transmitted)
Ingestion/ Fecal-oral route transmitted parasites
Intestinal protozoans
STHs
C. sinensis
D. latum
E. vermicularis
Fasciolopsis buski
F. hepatica
P. westermani
T. spiralis
T. saginata
T. solium
Skin transmitted parasites
Hookworms, S. stercoralis
Schistosoma spp. (direct contact)
Blood protozoans, filarial worms (inoculation)
Sexual contact transmitted parasites
E. histolytica
G. lambia
Trichomonas vaginalis
Kissing/ sharing contaminated drinking utensils transmitted parasites
Entamoeba gingivalis
Congenital transmitted parasites
Plasmodium spp., T. gondii
Inhalation transmitted parasites
E. vermicularis
Latrogenic (transfusion transmitted) transmitted parasites
Plasmodium spp. (trophozoite-induced/ transfusion malaria)
How parasites cause damage to the body
Traumatic damage
Lytic necrosis
Competition for certain nutrients
Inflammatory reactions
Allergic manifestations
Neoplasia
Secondary infection
Lytic necrosis causing example parasites
E. histolytica
Leishmania spp.
Plasmodium spp
Trypanosoma cruzi
Toxoplasma gondiiCo
Competition for certain nutrients causing example of parasites
Pernicious anemia due to D. latum (B12)
Traumatic damage causing parasites
Hookworms
S. stercoralis
Schistosoma spp.
Ascaris
Taenia
Hookworm, S. stercoralis and cercarial larvae of Schistosoma spp. mode of traumatic damage
Damage to the skin by flariform larvae
Inflammatory reactions caused by parasites
Eosinophilia
Hemolytic, iron deficiency, pernicious anemia
Intestinal inflammation
Proliferation of RECs
Allergic manifestations of parasites
Anaphylaxis
Dermatitis
Eosinophilia
Urticaria
Neoplasia causing parasites
C. sinensis and Opsitorchis viverrini
(Cholangiocarcinoma)
S. haematobium
(Vesical carcinoma)
Bacterial and viral infections due to parasitosis
Secondary infection