Offit Quiz Flashcards
Explain why the COVID-19 vaccines must be used within 6 hours of opening the rubber stopper of the vaccine
the vaccine does not contain any preservatives
At what age is the Rotavirus vaccine given to children and how is it given
Two, four, and six months and it’s given to them orally
T/F: Children and people in low-risk age groups can transmit COVID-19 just as easily as older adults.
true
Vincent mentioned that most of the clinical studies made on the SARS-CoV-2 vaccine (and vaccines in general) were performed on participants 18 years of age and up. What was Offit’s response to this?
adults usually ranging from 40-55 years of age or who are being treated in nursing homes are more likely to be infected by the SARS-Cov-2 virus. Individuals of 21 years old have been shown a mortality of 0.08% against COVID-19.
What was one thing we should take away from this pandemic?
We need to set up an international surveillance system to be able to detect if a virus like this pops up so we are prepared with a plan before a world wide outbreak occurs. We should also develop sequencing at an international level if a viral variant pops up.
What is the difference between a licensed vaccine and one under emergency use authorization?
The difference is the length of follow up for efficacy (e.g. when COVID-19 vaccine was released the reports could tell us they were effective for 2-3 months but this is not enough for a licensed vaccine)
What is the difference between vaccine efficacy and efficiency?
Efficacy refers to how well a vaccine does in a controlled environment (laboratory/ trials), while efficiency refers to how well a vaccine does in the real-world (highly depends on how well distributors maintain protocols for vaccine storage).
What Baltimore Classification does Rotavirus fall under?
Class 3 ( because it is a dsRNA virus)
Regarding safety follow up, how many weeks should pass before a vaccine recipient is considered safe?
6 weeks
What would be the best testing method for identifying the number of previously infected individuals of COVID-19? Why?
A) qRT-PCR
B) Antibody Surveillance
C) Antigen Tests
D) mRNA vaccine
B
because not everyone infected was administered a diagnostic test
Why is it challenging to completely eradicate the Rotavirus even with vaccines available?
because the vaccine is given in 2 or 3 doses to reach full immunity which could be a problem for people in underdeveloped countries
How is the SARS-CoV-2 pandemic similar to polio outbreak in the 1950s according to Offit?
- people are scared of the vaccines
- the have similar R0 values
- primarily transmitted by asymptomatic indiv
The rotavirus vaccine is a type of inactivated vaccine administered to children between the four to seven months of age.
False
What side effect was the major concern with the RotaShield vaccine?
Intussusception
Which wildtype(s) of poliovirus have been eradicated worldwide?
A) Type 1 B) Type 2 C) Type 3 D) Answer A and B only E) Answer B and C only F) None have been eradicated
E
