Oesophageal Problems Flashcards
what vertebral level does the oesophagus originate
C6
What are the symptoms of oesophageal disease?
Dysphagia
Dyspepsia (Heartburn)
Regurgitation
Painful swallow
What is dysphagia?
DIFFICULTY swallowing
What does a short history of progressive dysphagia first to solids and then liquids suggest? What is the most appropriate investigation?
Mechanical stricture
Urgent ODG (endoscopy)
What does a long history of slow onset dysphagia to both solids and liquids suggest? What is the most appropriate investigation?
Motility disorder
- OGD to exclude cancer
- Barium swallow rarely performed now
What is heartburn?
Retrosternal/Epigastric burning sensation due to acid reflux. Pain is made worse by lying down
What is regurgitation? What conditions does it occur in?
Reflux of oesophageal contents into the mouth/pharynx Occurs in reflux disease + oesophageal strictures
What is odynophagia? What condition does it indicate?
Painful swallow
Oesphagitis caused by GORD/infection
- candida in HIV patients
what is GORD?
Gastro-oesophageal reflux disease
- gastric acid from stomach leaks back up into the oesophagus
- lower oesophageal spincter relaxes more frequently than it should
What is the major symptom of GORD?
Heartburn- burning retrosternal pain
- worse after meals
- worse lying down / bending over
May also present with regurgitation + odynophagia.
How is the diagnosis of GORD made?
The history
risk factors for GORD
male
age
obesity
smoking
alcohol
When is an endoscopy (OGD) indicated?
New onset GORD > 55 years old or worsening despite PPI
patients with ALARM Symptoms
What are the ALARM Symptoms?
Anaemia
Loss of weight
Anorexia
Recent onset of progressive symptoms
Malena or haematemesis
Swallowing difficulty
what is the gold standard investigation for GORD?
when is it required?
24 hour pH monitoring
- patients where medical treatment fails and are being considered for surgery
- should be combined with oesophageal manometry to exclude motility disorders
What non-pharmacological management is indicated in GORD?
Weight loss
Smoking cessation
Avoidance of aggravating foods (e.g. coffee, fatty foods) + excess alcohol
What is the first line treatment for mild GORD?
Antacids, e.g. gavascon
What is the first line treatment for severe GORD or patients with complications?
PPIs e.g. omeprazole
surgical options for GORD
Fundoplication
- fundus is wrapped around gastro-oesophageal junction to create lower sphincter
- indicated for patients who dont respond to treatment / patient preference to avoid life long medication
What do H2 receptor antagonists do?
Relieve the symptoms of GORD. e.g. ranitidine