Odontogenic Tumors Flashcards
1
Q
Ameloblastoma
- Location
- Age, Sex
- Clinical
- Radiograph
- Histo/Subtypes/Grade
- Tx
A
- Anywhere
- Desmoplastic (post mand)
- Peripheral (ant max)
- 3rd-6th decade
- 3rd Unicystic 14%
- 4th Solid/conventional/multicystic (85%)
- 6th Peripheral 1%
- Clinical
- BL expansion
- Peripheral warty/painless
- Radiograph
- Only desmoplastic is radioopaque
- Histo
- Follicular (Invades perineural tissue)
- Plexiform (most common, fish net)
- Acanthomatous
- Granular Cell (younger, more aggressive)
- Demoplastic
- Basaloid
- Tx
- Resect mural unicystic, all solid/multicyst/conventional
- E&C other unicystic
- Excise peripheral
- Recurrence
- Resect solid 15%
- E&C solid 60%
- E&C mural
- E&C other unicys/peripheral 0%
2
Q
AOT (Adenomatoid Odontogenic Tumor)
- Location:
- Age/Gender:
- Clinical:
- Radio:
- Histo:
- Tx:
A
- Location: 2/3 canine
- Age/Gender: 2nd/3rd decades, 2/3 female
- Clinical: Asympto expansion
- Radio: IMPACTED tooth with pear shape with calcified flecks
- Histo: duct-like columnar
- Tx: E&C
3
Q
Calcifying Epithelial Odontogenic Tumor (CEOT)
“Pindborg tumor”
- Location
- Age, Sex
- Clinical
- Radio
- Histo
- Tx
A
- Posterior mandible, premolar
- Can form peripheral lesion in anterior gingiva
- 4th-6th decade
- Asympto expansion, slow growing
- Mixed, multi or unilocular, with snowflake pattern
- Leiseng rings calcifications, amyloid
- Resect (E&C 15% recurrence)
4
Q
Squamous ondontogenic tumor
- Location
- Age, sex
- Clinical
- Radio
- Histo
- Tx
A
- Ant max/post mand
- Any age
- May be painful, tooth mobile
- ERUPTED tooth with pear shaped RL
- Bland epithelium and fibrous stroma
- E&C
5
Q
Clear Cell odontogenic tumor (Carcinoma)
- Location
- Age, sex
- Histologically similar and confused with
- Histo
- Radio
A
- Malignant
- No data on location
- >50 years
- Confused with intraosseous mucoepidermoid carcinoma
- Islands of clear epithelial cells
- Ill-defined radiolucencies
6
Q
Primary Intraosseous Odontogenic Carcinoma
- Location
- Age/Gender
- Clinical
- Radio
- Histo
- Tx
- 5 year survival
A
- Posterior mandible
- 50’s
- NO ULCER. Can be painful, paresthesia, expansion, mobile teeth. Must have no mets/nodal involvement during 6 month window of diagnosis to be considered PIOC
- Ill-defined RL
- SCCa histologically
- Tx like SCCa including neck dissection
- 30-40% 5 year
7
Q
Malignant Ameloblastoma vs Ameloblastic Carcinoma
- Ameloblastoma malignant transformation rate
- Metastasizes but still has benign histo
- Doesn’t metastasize but has malignant histo
- Tx
A
- 1% malignant transformation
- Malignant (metastasizing) ameloblastoma
- Mets but has benign histo
- Resect vs E&C
- Ameloblastic Carcinoma
- Resection
8
Q
Ghost cell Odontogenic Tumor
- Malignant version of what odontogenic tumor
- Location
- Age
- Clinical
- Radio
- Histo
- Tx
A
- Malignant CEOT (Pindborg)
- Post Max
- 2-5 decades
- Painful expansion, paresthesia in mandible
- Multi/Uni locular RL
- Leiseng rings (calicifications), clear cells, squamous dysplasia
- Resection
9
Q
Ameloblastic Fibrosarcoma
- Malignant form of what tumor
- Location
- Age/Gender
- Clinical
- Radio
- Histo
- Tx
A
- Malignant AF (ameloblastic Fibrosarcoma)
- Post mand
- 2-3 decades
- Rapid painful expansion
- Ill defined, aggressive RL
- Epithelial component normal, mesenchymal stroma dysplasia
- Resection
10
Q
Odontogenic Myxoma
- Location
- Age
- Clinical
- Radio
- Histo
- Tx
A
- Mand>Max
- 3-4 decades
- Asymptomatic expansion
- Ill defined mixed, root divergence/resorption, step-ladder
- Stellate/Spindel stroma islands with mucoid
- Resection
11
Q
Odontogenic Fibroma
- Location
- Age/Gender
- Clinical
- Radio
- Histo
- Tx
A
- Ant max/post mand
- any age
- painless expansion
- RL or mixed, associated with periodontal ligament, root divergence/resorption
- fibrous tissue
- E&C
12
Q
Cementoblastoma
- Location
- Age/Gender/Race
- Clinical
- Radio
- Histo
- Tx
A
- Mandible molar/premolar roots
- 2-3 decades, no gender, no race
- Expansion and deep pain, tooth VITAL
- Round RD mostly replaces root with PDL space present. Hypercementosis has no PDL space
- Cementum, hyperchromatic nuclei
- EXT and curretage
13
Q
Central Granular Cell Odontogenic Tumor
- Location
- Age/Gender
- Clinical
- Radio
- Histo
- Tx
A
- Post max/mand
- >40yrs
- Expansion
- Well-defined mixed
- Eosinophilic granular cells and ontogenic epithelium
- E&C
14
Q
Ameloblastic Fibroma
- Location
- Age/Gender
- Clinical
- Radio
- Histo
- Tx
A
- Post mand
- 1-2 decades
- Sometimes expansion, asymptomatic
- Uni/multi locular RL, 50% with impacted tooth
- Strands of odontogenic epithelium with fibrous stroma
- E&C
15
Q
Ameloblastic Fibro-Odontoma
(Ondontoma precursur?)
- Location
- Age/Gender
- Clinical
- Radio
- Histo
- Tx
A
- Max=Mand
- 1-2 decades
- Asympto expansion
- Mixed with tooth fragments.
- Same as AF long strands odontogenic epithelium with fibrous stroma + dentin/enamel
- E&C