Odontogenic Tumors Flashcards

1
Q

Ameloblastoma

  • Location
  • Age, Sex
  • Clinical
  • Radiograph
  • Histo/Subtypes/Grade
  • Tx
A
  • Anywhere
    • Desmoplastic (post mand)
    • Peripheral (ant max)
  • 3rd-6th decade
    • 3rd Unicystic 14%
    • 4th Solid/conventional/multicystic (85%)
    • 6th Peripheral 1%
  • Clinical
    • BL expansion
    • Peripheral warty/painless
  • Radiograph
    • Only desmoplastic is radioopaque
  • Histo
    • Follicular (Invades perineural tissue)
    • Plexiform (most common, fish net)
    • Acanthomatous
    • Granular Cell (younger, more aggressive)
    • Demoplastic
    • Basaloid
  • Tx
    • Resect mural unicystic, all solid/multicyst/conventional
    • E&C other unicystic
    • Excise peripheral
  • Recurrence
    • Resect solid 15%
    • E&C solid 60%
    • E&C mural
    • E&C other unicys/peripheral 0%
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2
Q

AOT (Adenomatoid Odontogenic Tumor)

  • Location:
  • Age/Gender:
  • Clinical:
  • Radio:
  • Histo:
  • Tx:
A
  • Location: 2/3 canine
  • Age/Gender: 2nd/3rd decades, 2/3 female
  • Clinical: Asympto expansion
  • Radio: IMPACTED tooth with pear shape with calcified flecks
  • Histo: duct-like columnar
  • Tx: E&C
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3
Q

Calcifying Epithelial Odontogenic Tumor (CEOT)

“Pindborg tumor”

  • Location
  • Age, Sex
  • Clinical
  • Radio
  • Histo
  • Tx
A
  • Posterior mandible, premolar
    • Can form peripheral lesion in anterior gingiva
  • 4th-6th decade
  • Asympto expansion, slow growing
  • Mixed, multi or unilocular, with snowflake pattern
  • Leiseng rings calcifications, amyloid
  • Resect (E&C 15% recurrence)
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4
Q

Squamous ondontogenic tumor

  • Location
  • Age, sex
  • Clinical
  • Radio
  • Histo
  • Tx
A
  • Ant max/post mand
  • Any age
  • May be painful, tooth mobile
  • ERUPTED tooth with pear shaped RL
  • Bland epithelium and fibrous stroma
  • E&C
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5
Q

Clear Cell odontogenic tumor (Carcinoma)

  • Location
  • Age, sex
  • Histologically similar and confused with
  • Histo
  • Radio
A
  • Malignant
  • No data on location
  • >50 years
  • Confused with intraosseous mucoepidermoid carcinoma
  • Islands of clear epithelial cells
  • Ill-defined radiolucencies
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6
Q

Primary Intraosseous Odontogenic Carcinoma

  • Location
  • Age/Gender
  • Clinical
  • Radio
  • Histo
  • Tx
  • 5 year survival
A
  • Posterior mandible
  • 50’s
  • NO ULCER. Can be painful, paresthesia, expansion, mobile teeth. Must have no mets/nodal involvement during 6 month window of diagnosis to be considered PIOC
  • Ill-defined RL
  • SCCa histologically
  • Tx like SCCa including neck dissection
  • 30-40% 5 year
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7
Q

Malignant Ameloblastoma vs Ameloblastic Carcinoma

  • Ameloblastoma malignant transformation rate
  • Metastasizes but still has benign histo
  • Doesn’t metastasize but has malignant histo
  • Tx
A
  • 1% malignant transformation
  • Malignant (metastasizing) ameloblastoma
    • Mets but has benign histo
    • Resect vs E&C
  • Ameloblastic Carcinoma
    • Resection
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8
Q

Ghost cell Odontogenic Tumor

  • Malignant version of what odontogenic tumor
  • Location
  • Age
  • Clinical
  • Radio
  • Histo
  • Tx
A
  • Malignant CEOT (Pindborg)
  • Post Max
  • 2-5 decades
  • Painful expansion, paresthesia in mandible
  • Multi/Uni locular RL
  • Leiseng rings (calicifications), clear cells, squamous dysplasia
  • Resection
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9
Q

Ameloblastic Fibrosarcoma

  • Malignant form of what tumor
  • Location
  • Age/Gender
  • Clinical
  • Radio
  • Histo
  • Tx
A
  • Malignant AF (ameloblastic Fibrosarcoma)
  • Post mand
  • 2-3 decades
  • Rapid painful expansion
  • Ill defined, aggressive RL
  • Epithelial component normal, mesenchymal stroma dysplasia
  • Resection
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10
Q

Odontogenic Myxoma

  • Location
  • Age
  • Clinical
  • Radio
  • Histo
  • Tx
A
  • Mand>Max
  • 3-4 decades
  • Asymptomatic expansion
  • Ill defined mixed, root divergence/resorption, step-ladder
  • Stellate/Spindel stroma islands with mucoid
  • Resection
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11
Q

Odontogenic Fibroma

  • Location
  • Age/Gender
  • Clinical
  • Radio
  • Histo
  • Tx
A
  • Ant max/post mand
  • any age
  • painless expansion
  • RL or mixed, associated with periodontal ligament, root divergence/resorption
  • fibrous tissue
  • E&C
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12
Q

Cementoblastoma

  • Location
  • Age/Gender/Race
  • Clinical
  • Radio
  • Histo
  • Tx
A
  • Mandible molar/premolar roots
  • 2-3 decades, no gender, no race
  • Expansion and deep pain, tooth VITAL
  • Round RD mostly replaces root with PDL space present. Hypercementosis has no PDL space
  • Cementum, hyperchromatic nuclei
  • EXT and curretage
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13
Q

Central Granular Cell Odontogenic Tumor

  • Location
  • Age/Gender
  • Clinical
  • Radio
  • Histo
  • Tx
A
  • Post max/mand
  • >40yrs
  • Expansion
  • Well-defined mixed
  • Eosinophilic granular cells and ontogenic epithelium
  • E&C
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14
Q

Ameloblastic Fibroma

  • Location
  • Age/Gender
  • Clinical
  • Radio
  • Histo
  • Tx
A
  • Post mand
  • 1-2 decades
  • Sometimes expansion, asymptomatic
  • Uni/multi locular RL, 50% with impacted tooth
  • Strands of odontogenic epithelium with fibrous stroma
  • E&C
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15
Q

Ameloblastic Fibro-Odontoma

(Ondontoma precursur?)

  • Location
  • Age/Gender
  • Clinical
  • Radio
  • Histo
  • Tx
A
  • Max=Mand
  • 1-2 decades
  • Asympto expansion
  • Mixed with tooth fragments.
  • Same as AF long strands odontogenic epithelium with fibrous stroma + dentin/enamel
  • E&C
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16
Q

Odontoma

Most common odontogenic tumor

  • Location
  • Age
  • Clinical
  • Radio
  • Histo
  • Tx
A
  • Anterior maxilla = Compound
  • Posterior max/mand = Complex
  • 1-2 decades
  • Asympto
  • RD with lucent rim = Complex
  • Collection of tooth structures = Compound
  • Tooth structures in fibrous matrix
  • E&C
17
Q

Calcifying Cystic Odontogenic Tumor (Gorlin Cyst)

  • Location
  • Age
  • Clinical
  • Radio
  • Histo
  • Tx
A
  • Bimodal 2-3 decades, 6-7 decades
  • Swelling and gingival tender
  • Uni/Multi loc RL
  • Stellate reticulum with ghost cells
  • E&C