Odontogenic Neoplasms Flashcards

1
Q

3 Tumors of odontogenic epithelium

A
  1. Ameloblastoma
  2. Adenoid Odontogenic Tumor (AOT)
  3. Calcifying Epithelial Odontogenic Tumor (CEOT)
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2
Q

3 Mixed tumors of odontogenic epithelium and odontogenic ectomesenchyme

A
  1. Ameloblastic fibroma
  2. Ameloblastic fibro-odontoma
  3. Odontoma
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3
Q

2 Tumors of odontogenic mesenchyme

A
  1. Odontogenic myxoma

2. Cementoblastoma

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4
Q

The frequency of this tumor is equal to the combined frequency of all other odontogenic tumors

A

Ameloblastoma

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5
Q

What feature of an ameloblastoma can be dramatic?

A

Expansion

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6
Q

Most common area for ameloblastoma?

A

Posterior mandible (molar/ramus region)

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7
Q

What is the radiographic appearance of ameloblastoma?

A

“Soap bubble or honeycomb”

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8
Q

Do the lesional cells of an ameloblastoma make enamel?

A

No

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9
Q

2 Most common histological patterns of ameloblastoma?

A
  1. Follicular

2. Plexiform

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10
Q

What do you see in the histology of an ameloblastoma?

A

Tumor islands

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11
Q

What type of cells are at the periphery of tumor islands in an ameloblastoma? Are the nuclei polarized toward or away from the basement membrane?

A

Cuboidal or columnar cells

Away from

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12
Q

Ameloblastoma insinuates through _____. This is the reason for an ___ ___ ____

A

Trabeculae

En bloc resection

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13
Q

Why do maxillary ameloblastomas have to be treated more aggressively?

A

Because of anatomic location (vital structures)

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14
Q

Prognosis for ameloblastoma?

A

Guarded

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15
Q

When is an ameloblastoma more likely to be fatal?

A

When it is in the maxilla

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16
Q

What is the soft tissue variant of an ameloblastoma?

A

Peripheral ameloblastoma

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17
Q

What is the histological difference between an ameloblastoma and a peripheral ameloblastoma?

A

The peripheral is located under the surface epithelium

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18
Q

Treatment for a peripheral ameloblastoma

A

The biopsy is often curative

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19
Q

Are most patients with Adenomatoid Odontogenic Tumor (AOT) old or young?

A

Young

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20
Q

AOTs have a ____ predilection, are mostly in the ____ (anterior/posterior) ______ (maxilla/mandible), and are often associated with ____

A

Female
Anterior
Maxilla
Impacted teeth

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21
Q

AOTs often cause _____ of roots

A

Divergence

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22
Q

An AOT has a well defined ____

A

Capsule

23
Q

Which stratum layer will you find a Calcifying Epithelial Odontogenic Tumor (CEOT) in?

A

Stratum intermedium

24
Q

CEOTs are often in the ____ (anterior/posterior) _____ (maxilla/mandible)

A

Posterior mandible

25
Q

Radiographically, a CEOT is often ________ when small and _____ when large

A

Well-circumscribed

Multilocular

26
Q

What type of radiographic pattern is seen with a CEOT?

A

“Driven snow”

27
Q

The calcifications associated with a CEOT are called ___ ___

A

Liesegang rings (lamellated)

28
Q

Is radical surgery warranted for a CEOT?

A

No

29
Q

When the epithelial and ectomesenchymal cells are both neoplastic

A

Ameloblastic fibroma

30
Q

Ameloblastic fibromas are typically seen in _____ (older/younger) patients, and are often seen in the _____ (anterior/posterior) ____ (maxilla/mandible)

A

Younger

Posterior mandible

31
Q

The epithelial proliferation of ameloblastic fibromas resembles ____ ____

A

Dental papilla

32
Q

The myxoid connective tissue of an ameloblastic fibroma contains strands and islands of odontogenic epithelium resembling ___ ____

A

Dental lamina

33
Q

An ameloblastic fibro-odontoma is often seen in ____ (older/younger) patients. Where is it often seen?

A

Younger

Equal frequency in the mandible and maxilla

34
Q

An ameloblastic fibro-odontoma often overlies a(n) ____ ____

A

Impacted tooth

35
Q

The histology of an ameloblastic fibro-odontoma is the same as:

A

An ameloblastic fibroma with an odontoma

36
Q

What type of odontoma is usually associated with an ameloblastic fibro-odontoma?

A

The complex type

37
Q

2 forms of an odontoma and where they’re located

A
  1. Compound (usually anterior)

2. Complex (usually posterior)

38
Q

An odontoma is probably a(n) ____ ____ rather than a true neoplasm

A

Odontogenic hamartoma

39
Q

Odontomas are typically seen in ____ (older/younger) patients and are slightly more frequent in the _____ (maxilla/mandible)

A

Younger

Maxilla

40
Q

Radiographically, a compound odontoma is a collection of

A

Small malformed teeth surrounded by a radiolucent rim

41
Q

Radiographically, a complex odontoma is:

A

A calcified mass with the same density of tooth structure (if it is fully formed)

42
Q

Histologically, what is seen in a complex odontoma?

A

A mix of dentin, enamel matrix, cementum, odontogenic epithelium and dental papilla

43
Q

Benign neoplasm assumed to be of odontogenic origin because it only affects the jaw bones as a central lesion - no other bones

A

Odontogenic myxoma

44
Q

Odontogenic myxomas are slightly more common in the ____ (maxilla/mandible)

A

Mandible

45
Q

Odontogenic myxomas have a ____ ____ appearance

A

Soap bubble

46
Q

What is unique about odontogenic myxomas on a radiograph?

A

There are thin, wispy trabeculae of residual bone, often at right angles

47
Q

Treatment for an odontogenic myxoma if it is small? If it is large?

A

Small - curettage

Large - en bloc or segmental resection

48
Q

What contributes to the recurrence rate of an odontogenic myxoma?

A

Infiltration

49
Q

Cementoblastomas are usually seen in the _______ region

A

Mandibular molar (usually 1st molar)

50
Q

Cementoblastomas are often associated with ___ and ___

A

Pain and swelling

51
Q

Cementoblastomas often obscur the _______

A

Outline of the root

52
Q

What is a distinguishing histological feature of a cementoblastoma?

A

It is fused to the root

53
Q

Treatment for cementoblastoma

A

Surgically extract the involved tooth and enucleate the lesion (or endo, enucleation, and root amputation)