Odontogenic Cysts Flashcards

1
Q

3 Inflammatory Cysts

A
  1. Periapical (Radicular) Cyst
  2. Residual Periapical (Radicular) Cyst
  3. Buccal Bifurcation Cyst
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2
Q

8 Developmental Cysts

A
  1. Dentigerous Cyst
  2. Eruption Cyst
  3. Primordial Cyst
  4. Odontogenic Keratocyst (OKC)
  5. Gingival (alveolar) Cyst of the Newborn
  6. Gingival Cyst of the adult
  7. Lateral Periodontal Cyst
  8. Calcifying Odontogenic Cyst
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3
Q

Most common cyst of the jaws

A

Periapical cyst

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4
Q

How does a periapical cyst usually originate?

A

Due to inflammatory stimulation of the epithelial rests of Malassez

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5
Q

Teeth associated with a periapical cyst usually test _____ (vital/non-vital)

A

Non-vital

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6
Q

Why might a patient with a periapical cyst be experiencing pain?

A

If there is a secondary infection or if the cyst is large

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7
Q

A periapical cyst may also present as a ___ ___ cyst

A

Lateral radicular cyst

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8
Q

A periapical cyst shows inflamed granulation tissue or fibrous connective tissue lined by _______ (keratinized/non-keratinized) _____ ______ epithelium

A

Non-keratinized stratified squamous

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9
Q

If there is NO cyst lining, then a periapical cyst is referred to as a ____ _____

A

Periapical granuloma

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10
Q

Treatment for a periapical cyst

A
  1. Endo
  2. Apicoectomy
  3. Extraction
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11
Q

If a periapical cyst is not removed or resolved, then it may persist as a _____ _____

A

Residual cyst

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12
Q

Where will you see a residual cyst?

A

In the site of a previous extraction or endo treated tooth

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13
Q

Treatment for residual cyst

A

Enucleation

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14
Q

A cyst in the mandibular molars (mostly) that usually affects children

A

Buccal bifurcation cyst

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15
Q

You may see ____ ____ in a patient with a buccal bifurcation cyst

A

Proliferative periostitis

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16
Q

The histology of a buccal bifurcation cyst is similar to what other cyst?

A

Periapical

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17
Q

Treatment for a buccal birfurcation cyst?

A

Enucleation

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18
Q

Most common developmental odontogenic cyst

A

Dentigerous cyst

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19
Q

Most common cyst overall? 2nd most common?

A

Most - periapical

2nd - dentigerous

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20
Q

Why does a dentigerous cyst develop?

A

Due to accumulation of fluid between the crown and the reduced enamel epithelium, which eventually forms the epithelial lining of the cyst

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21
Q

What part of the tooth is a dentigerous cyst associated with?

A

The crown of an unerupted tooth

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22
Q

How can you distinguish between a dentigerous cyst and a hyperplastic dental follicle?

A

> 5 mm = cyst

< 5 mm = follicle

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23
Q

Most common tooth to have a dentigerous cyst? 2nd most? 3rd most?

A

Most - mandibular 3rds
2nd - maxillary canine
3rd - maxillary 3rds

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24
Q

Is a dentigerous cyst inflamed or uninflamed?

A

Uninflamed

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25
Q

Treatment for a dentigerous cyst

A

Remove tooth and cyst

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26
Q

If there are mucous cells in the lining of a dentigerous cyst, then they may explain:

A

Central (intraosseous) mucoepidermoid carcinoma

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27
Q

Dentigerous cyst that forms in the soft tissue overlying the crown of an erupting tooth (seen in children)

A

Eruption cyst

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28
Q

Eruption cysts can also be called ___ ___ due to their coloring

A

Eruption hematoma

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29
Q

Rare lesion that is thought to be histogenetically derived from degenerating tooth bud epithelium

A

Primordial cyst

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30
Q

A primordial cyst develops in place of:

A

A tooth, before any mineralized material is deposited

31
Q

What is mandatory when diagnosing a primordial cyst?

A

No history of extraction or surgery in the area

32
Q

The Europeans insist that primordial cysts are the same as ____

A

OKCs

33
Q

What type of epithelium is seen in primordial cysts?

A

Parakeratotic stratified squamous epithelium

34
Q

What type of basal cells are seen in primordial cysts

A

Hyperchromatic palisaded basal cells

35
Q

True/False: If the histology of a primordial cyst is that of an OKC, then the lesion will have the increased recurrence rate of OKC?

A

True

36
Q

OKCs can occur singly or can be associated with _____

A

Nevoid Basal Cell Carcinoma Syndrome (NBCCS)

37
Q

OKCs may resemble:

A

Primordial cysts, dentigerous cysts, residual cysts, or lateral periodontal cysts

38
Q

What area of the mouth do OKCs favor after the age of 70?

A

Anterior maxilla

39
Q

When might a patient have an OKC under the age of 10?

A

If they have a syndrome

40
Q

What area of the mouth is the most common for OKCs?

A

Posterior mandible

41
Q

3 criteria for OKCs

A
  1. Uniformly thin epithelial lining of stratified squamous epithelium 8-10 cells thick
  2. Corrugated paraketatin surface
  3. Palisaded basal cell layer
42
Q

Treatment of OKC if smaller? If larger?

A

Smaller - enucleate in one piece

Larger - marsupialization followed by enucleation

43
Q

Prognosis for OKC

A

Guarded

44
Q

The syndrome when multiple OKCs arise at an early age

A

Nevoid Basal Cell Carcinoma Syndrome

45
Q

Another name for NBCCS

A

Gorlin Syndrome

46
Q

NBCCS is autosomal ____

A

Dominant

47
Q

Clinical features of NBCCS

A

Enlarged occipitofrontal circumfrence, heavy brow ridges, broad nasal root, mild ocular hypertelorism

48
Q

Skin features of NBCCS

A

Milia and multiple epidermal cysts

1-2 mm shallow pits on palms/soles

49
Q

NBCCS have 5 features

A
  1. Are multiple
  2. Occur in unexposed and exposed skin
  3. Develop at an earlier age
  4. Often show melanin pigmentation
  5. Usually quiescent, a few are aggressive
50
Q

2 radiographic features that most patients with NBCCS show?

A
  1. Lamellar calcification of the falx cerebri

2. Bifid, fused or hypoplastic ribs

51
Q

Treatment for NBCCS

A

Remove OKCs and BCCs as needed

52
Q

Prognosis for NBCCS

A

Guarded

53
Q

“Dental lamina cyst”

A

Gingival cyst of the newborn

54
Q

What do gingival cysts of the newborn represent?

A

An enlarged version of the normal microcystic structures that arise from dental lamina rests (rests of Serres)

55
Q

What are the gingival cysts of the newborn called if they’re on the palatal raphe? If they’re laterally along the hard/soft palate?

A

Palatal raphe - Epstein’s pearls

Lateral of hard/soft palate - Bohn’s nodules

56
Q

What term encompasses Epstein’s pearls and Bohn’s nodules?

A

Palatal cyst of the newborn

57
Q

Clinical features of gingival cysts of the newborn? Usually which arch?

A

1-2mm yellow-white papules on the alveolar ridge of the newborn (usually maxillary)

58
Q

What type of debris will you find in the lining of a gingival cyst of the newborn

A

Keratin

59
Q

Why do gingival cysts of the newborn not require any treatment?

A

They self-marsupialize or involute/degenerate spontaneously

60
Q

Where are gingival cysts of the adult typically found?

A

Anterior segments of the jaws above or below the MGJ (usually facial)

61
Q

What radiographic changes are seen in gingival cysts of the adult?

A

Minimal, if any

62
Q

Treatment for gingival cysts of the adult

A

Conservative excision

63
Q

A non-keratinized developmental cyst occuring adjacent or lateral to the root of a tooth, probably arising from rests of dental lamina (rests of Serres)

A

Lateral periodontal cyst

64
Q

Most common area to see a lateral periodontal cyst

A

Mandibular premolar-canine-lateral incisor region

65
Q

What cyst does the lateral periodontal cyst look identical to in the histology?

A

Gingival cyst of the adult

66
Q

Treatment for a lateral periodontal cyst

A

Curettage

67
Q

Most Calcifying Odontogenic Cysts (Gorlin cysts) are seen in what region?

A

Anterior (incisor-canine region)

68
Q

Calcifying Odontogenic Cysts are usually _____

A

Intrabony

69
Q

Calcifying Odontogenic Cysts have 3 important radiographic features

A
  1. Scattered radiopacities
  2. Associated with impacted teeth
  3. Associated with odontoma
70
Q

The teeth in a Gorlin Cyst test ____

A

Vital

71
Q

A Gorlin cyst is histologically similar to a ____ ____ ____

A

Odontogenic Tumor Ameloblastoma

72
Q

Some lesional Gorlin cyst cells undergo ___ ___ change

A

“Ghost cell” (loss of nucleus exhibits ghostly remnant of nuclear outline)

73
Q

Treatment for Gorlin cyst

A

Enucleation and curettage