ODONTOGENESIS Flashcards

1
Q

4 STAGES REQUIRED FOR TOOTH FORMATION

A

Initiation Stage
Morphodifferentiation Stage
Histodifferentiation Stage
Apposition Stage

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2
Q

Bud stage
Formation of tooth germs
along the dental lamina

A

Initiation Stage

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3
Q

Differential
growth causes change in shape

A

Morphodifferentiation Stage

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4
Q

Bell stage
Specialization of cells

A

Histodifferentiation stage

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5
Q

Mineralization of tissues

A

Apposition Stage

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6
Q

Tooth Formation is dependent on:

A

*Genetic Factors
*Environmental Factors

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7
Q

Tooth Formation is dependent on:
hundreds to several
thousand genes likely involved

A

Genetic Factors

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8
Q

Tooth Formation is dependent on:
nutrition,
physical phenomenon, infection

A

Environmental Factors

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9
Q

 Oral epithelium thickens and
invaginates in to the mesenchyme to form a primary epithelial band
 Future dental arches

A

6TH week

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10
Q

 Primary epithelial band divides into two
processes: dental lamina and vestibular lamina

A

7th week

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11
Q
  • lingual; 1st to appear
  • contributes to the tooth
    development
A

Dental lamina

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12
Q
  • facial/buccal
  • cells rapidly enlarge to form a clef o vestibule between the cheeks and the tooth-bearing areas
A

Vestibular lamina

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13
Q

series of swellings develop on the deep
surface of the dental lamina
 tooth development proceeds in three stages: the bud, cap, and bell stages
 enamel organ appears as simple
spherical to avoid epithelial
condensation
 poorly morphodifferentiated and
histodifferentiated

A

8th week

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14
Q

 8th week
 dental lamina is a knob-like projection toward the mesoderm
 beginning of dental organ formation

A

BUD STAGE

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15
Q

 10th week
 morphogenesis has progressed
 the deeper surface of the dental organ
invaginating to form a cap-shaped structure
 enamel organ appearing poorly
histodifferentiated
 at this early stage, tooth development is
already possible to identify the
formative element of tooth and its
supporting tissues:  dental organ/ enamel organ  dental papilla  dental follicle/ dental sac

A

CAP STAGE

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16
Q

CAP STAGE

A

10TH WEEK

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17
Q

3 COMPONENTS OF THE TOOTH BUD AT CAP STAGE:

A

Dental organ
Dental papilla
Dental follicle

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18
Q

COMPONENT OF THE TOOTH BUD AT CAP STAGE:
forms the enamel

A

Dental organ

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19
Q

COMPONENT OF THE TOOTH BUD AT CAP STAGE:
forms the dentin and
pulp

A

Dental papilla

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20
Q

COMPONENT OF THE TOOTH BUD AT CAP STAGE:
forms the supporting structures of teeth

A

Dental follicle

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21
Q

3 COMPONENTS OF THE TOOTH AT EARLY CAP STAGE:

A

Dental organ
Dental papilla
Dental follicle

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22
Q

COMPONENT OF THE TOOTH AT EARLY CAP STAGE:
eventually forms enamel

A

Dental organ

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23
Q

COMPONENT OF THE TOOTH AT EARLY CAP STAGE:

Odontoblasts (periphery) =
dentin  Fibroblasts (center) = pulp

A

Dental papilla

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24
Q

COMPONENT OF THE TOOTH AT EARLY CAP STAGE:

Cementoblasts (inner) = cementum  Fibroblasts (middle) =
periodontal ligament  Osteoblasts (outer) = alveolar
bone

A

Dental follicle

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25
Q

Late during cap stage, dental organ histodifferentiated into morphogically and
functionally different components:

A

Stellate reticulum
External or outer enamel epithelium
Internal or inner enamel epithelium
Stratum intermedium

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26
Q
  • cells at the center of
    the dental organ
A

Stellate reticulum

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27
Q

tall cuboidal cells at the periphery of
the dental organ

A

External or outer enamel epithelium

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28
Q

columnar cells immediately adjacent to the dental papilla

A

Internal or inner enamel epithelium

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29
Q

epithelial cells
between the internal dental epithelium
and the newly formed stellate reticulum

A

Stratum intermedium

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30
Q

14th week
Further morphodifferentiation and
histodifferentiation
 Dental organ increases in size changes
in shape
 Invagination (IEE) becomes deeper

A

BELL STAGE

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31
Q

14th week
Area where the inner and the outer enamel epithelium come together
 Established the CEJ

A

CERVICAL LOOP

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32
Q

 During the early stages of tooth
development three transitory structures may be seen:
A. Enamel knot (Ahern’s knot)
B. Enamel navel
C. Enamel cord

A

TRANSITORY STRUCTURES

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33
Q

Localized mass cells in
the center of IEE

A

Enamel knot (Ahern’s knot)

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34
Q

 Slight indentation to the outer enamel
epithelium caused by the inward pull of the
enamel cord

A

Enamel navel

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35
Q

 Strand of cells seen at
the early bell stage extending from the stratum intermedium towards the outer enamel epithelium
 Together with the
enamel knot, form the
site of the future cusp tip or incisal edge

A

Enamel cord

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36
Q

 Associated with the formation of the
dental hard tissues, commencing at
about the 18th week
 Dentin formation always precedes enamel formation

A

LATE BELL STAGE (appositional stage)

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37
Q

Also known as cup stage

A

Proliferation stage

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38
Q

primitive oral cavity ○ Lined by stratified
squamous epithelium - oral
ectoderm

A

Stomodeum

39
Q

Stomodeum lined by stratified squamous epithelium called ___.

A

oral ectoderm

40
Q

○ oral ectoderm endoderm
contacts with the foregut

A

Buccopharyngeal membrane

41
Q
  • the
    buccopharyngeal membrane
    ruptures
A

27th day of gestation

42
Q

○ connective tissue cells
underlying the oral ectoderm
○ Essential for the face and the
teeth

A

Neural crest or ectomesenchyme

43
Q

first deciduous teeth to erupt

A

Mandibular Central Incisors

44
Q

○ Appears at the 37th day of
development
○ A band of odontogenic
epithelium that forms around
the mouth
○ Horseshoe shaped

A

Primary Epithelial band

45
Q

○ Localized thickenings
within the primary
epithelial bonds ○ Key feature of
initiation of tooth
development

A

Placodes

46
Q

PEB gives rise to:

A

Dental lamina Vestibular lamina

47
Q

It first forms from PEB

A

Dental lamina

48
Q

forms after Dental
lamina

A

Vestibular lamina

49
Q

○ Embryo is 6 weeks wold
certain areas of basal cell of
the oral ectoderm proliferate
rapidly
○ Leads to dental lamina
invading the underlying
ectomesenchyme
○ Serves as primordium of the
ectodermal portion

A

Dental Lamina

50
Q
  • first
    recognizable stage in
    embryonic
    development
A

Primordium

51
Q

6 or 6 ½ weeks of
tooth development

A

First sign of tooth
development

52
Q

When is development of first permanent molar initiated?

A

at the fourth month of
utero

53
Q

When does deciduous teeth develop
from lingual extension of
the free end of the dental
lamina

A

5th month in utero to the
10th month of age

54
Q

Fate of the dental lamina

A

Extends over 5 years

55
Q

It hollows and forms the oral
vestibule

A

Vestibular Lamina/Lip furrow
band

56
Q

What develops first in the tooth development

A

Mandibular teeth

57
Q

The tooth are named after ___________

A

the shape of epithelium

58
Q

Earliest evidence of tooth

A

Tooth Germ

59
Q

Development stages

A
  1. Growth stage
  2. Calcification stage
  3. Eruption stage
60
Q

Under growth stage:

A

a. Initiation stage
b. Proliferation stage
c. Histodifferentiation stage
d.Morphodifferentiation stage
e. Apposition stage

61
Q

The epithelium of the dental lamina
is separated from the underlying
ectomesenchyme

A

Initiation Stage (bud stage)

62
Q

Ovoid swellings arise from 10
different points -> future position ○ Primordia of enamel organ

A

Initiation Stage (bud stage)

63
Q

○Consist of :
■ Low columnar cells
■ Centrally located
polygonal cell

A

Enamel organ

64
Q

○ Cells around the tooth bud
undergo mitosis
■ Results to migration
of migration of neural
crest cells to
ectomesenchymal
cells that surrounds
the tooth bud

A

Enamel organ

65
Q

○ Area of ectomesenchymal
condensation, subjacent to
the enamel organ

A

Dental Papilla

66
Q

Cells of dental papilla forms:

A

Dentin and pulp

67
Q

condensed
mesenchyme that surrounds the
tooth bud

A

Dental sac

68
Q

Dental sac forms

A

■ Cementum
■ Periodontal ligament

69
Q

Parts of tooth bud:

A

■ dental/ enamel
organ
■ Dental papilla
■ Dental sac

70
Q

Part of tooth bud:
produce
enamel

A

dental/ enamel
organ

71
Q

Part of tooth bud:
produce pulp and
dentin

A

Dental papilla

72
Q

Part of tooth bud:
produce
cementum and
periodontal ligament

A

Dental sac

73
Q

a soft
connective tissue between the inner
wall of the alveolar socket and the
roots of the teeth.

A

Periodontal ligament

74
Q

Embryonic cells of dental/enamel organ-ameloblasts-enamel

A

ectoderm

75
Q

Embryonic cells of dental papilla-connective tissue- odontoblast - dentin and pulp

A

ectomesenchyme

76
Q

Embryonic cells of dental sac or follicle-connective tissue-cementum and periodontal ligament

A

ectomesenchyme

77
Q

A slight indentation to the
outside epithelium

A

Enamel navel

78
Q

○ Reservoir of dividing cells ○ Cells in the center of the
enamel organ

A

Enamel knot

79
Q

○ Vertical extension of the
enamel knot ○ seems to divide the dental
organ into two

A

Enamel cord(temporary structure)

80
Q

○ Concavity filled with
connective tissue

A

Enamel niche

81
Q

○ Formative organ of the dentin
and pulp

A

Dental papilla

82
Q

○ Surrounds the dental organ
○ Made up of mesenchymal sac
○ Important in the formation of
cementum and periodontal
ligament

A

Dental Sac

83
Q

○ Basement membrane that
separates the enamel organ
and the dental papilla ○ Future DEJ (dentino enamel
junction)

A

Membrana preformativa

84
Q

○ Consist of cells that
differentiate prior to
amelogenesis

A

Inner enamel epithelium

85
Q

○ Cells in the center of the
organ
○ Star shaped cells

A

Stellate reticulum

86
Q

○ Flattened low cuboidal cells
○ Provides a rich nutritional
supply for intense metabolic
activity

A

Outer epithelium

87
Q

Advance bell stage:
○ Rises from the cervical
portion of the enamel organ
○ Enamel organ forms the
HERS which is essential for
root formation

A

Hertwig’s epithelial root sheath
(HERS)

88
Q

Advance bell stage:
Where inner and outer
epithelia comes together

A

Cervical loop

89
Q

Advance bell stage:
○ Periodontal ligament of an
erupted teeth where
remnants are found ■ Remnants - lost
structure of HERS

A

Rest of malassez

90
Q

Fusion of crown

A

Fusion

91
Q

Globule of enamel is present

A

Dens Evaginatus

92
Q

○ Hypoplasia
○ Notches are present

A

Hutchinson’s teeth

93
Q

○ Small island of enamel
usually present in the CEJ

A

Enamel pearls

94
Q

○ Angulation of tooth

A

Dilaceration