ODONTOGENESIS Flashcards
4 STAGES REQUIRED FOR TOOTH FORMATION
Initiation Stage
Morphodifferentiation Stage
Histodifferentiation Stage
Apposition Stage
Bud stage
Formation of tooth germs
along the dental lamina
Initiation Stage
Differential
growth causes change in shape
Morphodifferentiation Stage
Bell stage
Specialization of cells
Histodifferentiation stage
Mineralization of tissues
Apposition Stage
Tooth Formation is dependent on:
*Genetic Factors
*Environmental Factors
Tooth Formation is dependent on:
hundreds to several
thousand genes likely involved
Genetic Factors
Tooth Formation is dependent on:
nutrition,
physical phenomenon, infection
Environmental Factors
Oral epithelium thickens and
invaginates in to the mesenchyme to form a primary epithelial band
Future dental arches
6TH week
Primary epithelial band divides into two
processes: dental lamina and vestibular lamina
7th week
- lingual; 1st to appear
- contributes to the tooth
development
Dental lamina
- facial/buccal
- cells rapidly enlarge to form a clef o vestibule between the cheeks and the tooth-bearing areas
Vestibular lamina
series of swellings develop on the deep
surface of the dental lamina
tooth development proceeds in three stages: the bud, cap, and bell stages
enamel organ appears as simple
spherical to avoid epithelial
condensation
poorly morphodifferentiated and
histodifferentiated
8th week
8th week
dental lamina is a knob-like projection toward the mesoderm
beginning of dental organ formation
BUD STAGE
10th week
morphogenesis has progressed
the deeper surface of the dental organ
invaginating to form a cap-shaped structure
enamel organ appearing poorly
histodifferentiated
at this early stage, tooth development is
already possible to identify the
formative element of tooth and its
supporting tissues: dental organ/ enamel organ dental papilla dental follicle/ dental sac
CAP STAGE
CAP STAGE
10TH WEEK
3 COMPONENTS OF THE TOOTH BUD AT CAP STAGE:
Dental organ
Dental papilla
Dental follicle
COMPONENT OF THE TOOTH BUD AT CAP STAGE:
forms the enamel
Dental organ
COMPONENT OF THE TOOTH BUD AT CAP STAGE:
forms the dentin and
pulp
Dental papilla
COMPONENT OF THE TOOTH BUD AT CAP STAGE:
forms the supporting structures of teeth
Dental follicle
3 COMPONENTS OF THE TOOTH AT EARLY CAP STAGE:
Dental organ
Dental papilla
Dental follicle
COMPONENT OF THE TOOTH AT EARLY CAP STAGE:
eventually forms enamel
Dental organ
COMPONENT OF THE TOOTH AT EARLY CAP STAGE:
Odontoblasts (periphery) =
dentin Fibroblasts (center) = pulp
Dental papilla
COMPONENT OF THE TOOTH AT EARLY CAP STAGE:
Cementoblasts (inner) = cementum Fibroblasts (middle) =
periodontal ligament Osteoblasts (outer) = alveolar
bone
Dental follicle
Late during cap stage, dental organ histodifferentiated into morphogically and
functionally different components:
Stellate reticulum
External or outer enamel epithelium
Internal or inner enamel epithelium
Stratum intermedium
- cells at the center of
the dental organ
Stellate reticulum
tall cuboidal cells at the periphery of
the dental organ
External or outer enamel epithelium
columnar cells immediately adjacent to the dental papilla
Internal or inner enamel epithelium
epithelial cells
between the internal dental epithelium
and the newly formed stellate reticulum
Stratum intermedium
14th week
Further morphodifferentiation and
histodifferentiation
Dental organ increases in size changes
in shape
Invagination (IEE) becomes deeper
BELL STAGE
14th week
Area where the inner and the outer enamel epithelium come together
Established the CEJ
CERVICAL LOOP
During the early stages of tooth
development three transitory structures may be seen:
A. Enamel knot (Ahern’s knot)
B. Enamel navel
C. Enamel cord
TRANSITORY STRUCTURES
Localized mass cells in
the center of IEE
Enamel knot (Ahern’s knot)
Slight indentation to the outer enamel
epithelium caused by the inward pull of the
enamel cord
Enamel navel
Strand of cells seen at
the early bell stage extending from the stratum intermedium towards the outer enamel epithelium
Together with the
enamel knot, form the
site of the future cusp tip or incisal edge
Enamel cord
Associated with the formation of the
dental hard tissues, commencing at
about the 18th week
Dentin formation always precedes enamel formation
LATE BELL STAGE (appositional stage)
Also known as cup stage
Proliferation stage