OD & Antidotes Flashcards
1
Q
Opioids (antidote & Sx)
A
Naloxone
- pin point pupils
- respiratory depression
- coma
2
Q
Paracetamol
A
Acetylcysteine
- N&V
- hepatocellular necrosis
- renal tubular necrosis (rare)
3
Q
Iron
A
Desferrioxamine mesilate
- N&V
- abdominal pain
- haematemesis
4
Q
Theophylline
A
Activated charcoal
Ondansetron (for vomiting)
- hyperglycaemia
- dilated pupils
- severe & intractable vomiting
- convulsions
5
Q
SSRIs
A
Activated charcoal
- N&V
- tremor
- nystagmus
- serotonin syndrome
6
Q
warfarin antidote
A
- phytomenadione (vitamin K)
- given by slow IV injection
- INR 5-8 & no bleeding: WH 1 or 2 doses, reduce subsequent maintenance dose
- INR 5-8 & minor bleeding: phytomenadione, stop warfarin, restart when INR <5
7
Q
apixaban
A
andexanet alfa
8
Q
rivaroxaban
A
andexanet alfa
9
Q
dabigatran
A
idarucizumab
10
Q
A
