Ocular Surface Disease (M1) Flashcards
What percentage of people in North America will have dry eye?
20%
Who are the people most likely to get dry eye?
- females (esp menopausal and postmenopausal)
- Autoimmune disease pts
- Systemic medications (antihistamines, antidepressants, Hormone Replacement Therapy)
- Contact lens wearers
- Refractive surgery patients
When there is dry eye, is there an increase or decrease in tear osmolarity?
increase
What are the four most common symptoms of dry eye?
- grittiness
- foreign body sensation
- tearing
- transient blur
What are the enlarged sebaceous glands posterior to the eyelashes called? 1. What do they secrete? 2
- meibomian glands
2. lipid
What percentage of meibomian glands are active at one time? 1. How can these glands be viewed? 2
- 45%
2. transillumination
What are the signs of Seborrheic MGD?
- hypersecretion
2. normal gland morphology
What are the signs of obstructive MGD?
- low secretion and gland drop-out (stenosis)
2. Increased osmolarity
What are the signs of obstructive with sicca MGD?
- low secretion and gland drop-out (stenosis)
- Increased osmolarity
- Decreased Schimer
What are the non-Rx treatments for dry eye?
- environment control
- Tear substitutes
- Nutriceutical (Omega fatty acid supplementation)
- Treat concurrent lid disease
What are the products given to dry eye patients that require anti-inflammatory treatment (and how long are each taken)?
- topical steroids (immediate relief, not taken long)
2. topical cyclosporine, Restasis (after steroids and taken for rest of life)
What treatment for dry eye increases mucin production and is not available in the U.S.?
secretagogs
What is given to the patient if they are unresponsive to topical immunosuppressive agents for dry eye? 1. What does it contain? 2
- autologous serum
2. neutrotrophic growth factor, epidermal growth factor, vit A, fibronectin, and lysozyme
What promotes an anti-inflammatory environment in dry eye and is in flax seed oil and fish oil?
omega fatty acids
What is a type of punctal plug that has the rim rest on the lid margin and has a tapered shaft?
Eagle Flex Plug