Ocular Disorders: Anterior Flashcards
Indications for Topical Ophthalmic Steroids
- Inflammatory condiSons of the anterior segment of the globe
- Ex// allergic conjuncSviSs, uveiSs, episcleriSs, scleriSs, phlyctenulosis,
superficial punctate keraSSs, intersSSal keraSSs, vernal conjuncSviSs, & post-
op inflammaSon
Contraindications for Topical Ophthalmic Steroids
- HypersensiSvity reacSons
- Microbial (bacterial/viral/fungal) keraSSs
- Ocular hypertension
- Glaucoma
T/F Topical Ophthalmic Steroids Should be managed by Ophthalmology
T
Topical Ophthalmic Steroids
Serious Adverse Effects
- Cataracts (prolonged use)
- Corneal perforation
- Exacerbation of viral infections (herpes simplex)
- Glaucoma
- Immunosuppression
Corneal Abrasion
Clinical Presentation
- Unilateral symptoms
- Foreign body sensation
- Eye pain
- Inability to open eye
- Photophobia
- Excessive tearing
Corneal Abrasion
Diagnosis
- No obvious laceration on initial exam
- Assess visual acuity
- Instill topical anesthetic
- Fluorescein & Wood’s lamp
- Slit lamp examination if no obvious abrasion
- If penetrating injury suspected , CT or MRI
- If ulcer suspected, obtain cultures prior to antibiotics
Corneal Abrasion
Management - prophylaxis
- Prophylaxis
- Topical antibiotics until patient is
asymptomatic - Ciprofloxacin, tobramycin,
trimethoprim/polymyxin B
Corneal Abrasion management
- Small abrasions can be managed outpatient
- Ice compresses for 24-48 hrs to reduce edema
- Warm compresses
- Eye rest
- Close follow-up until healed
Abrasions from contact lenses Tx
- Prophylactic topical antibiotics
- Pseudomonas aeruginosa
Abrasions from vegetable matter Tx
Fungal
* Natamycin – topical ophthalmic antifungal
Corneal Ulcer
- Ophthalmologic emergency
- ~20,000 cases per year in US
- Viral occur on a previously intact corneal epithelium
- Bacterial generally follow a traumatic break in the
corneal epithelium
Corneal Ulcer Tx
Topical ophthalmic corticosteroid = funga
Corneal Ulcer presentation
- Redness
- Severe pain
- Foreign body sensation
- Tearing
- Discharge
- Blurred vision
- Photophobia
- Swelling of the eyelids
- A white spot on the cornea
What pattern will a corneal abrasion take if it is HSV?
Dendritic pattern if HSV
Corneal Foreign Body
Presentation
- Red eye
- Pain
- Foreign body sensaSon
- Photophobia
- Tearing
Corneal Foreign Body diagnosis
Dilated examination by ophthalmology
* InfecSous corneal infiltrates/ulcers generally
require scrapings for smears & cultures
* Exclude intraocular foreign body
* Orbital CT
* B-scan ultrasound
* Ultrasound biomicroscopy (UBM)
* If metallic object suspected, consider
x-ray as initial study
Do NOT patch a corneal foreign body if:
- A chance of a perforation of the globe exists
- A corneal infiltrate is present
- A chance of a retained intraocular foreign
body is possible
Keratitis
Infection/Inflammation of the cornea
Keratitis
Epidemiology/Etiology
- Emergent Condition
- 25,000 cases in US/year
- Complication of contact lens use
& refractive corneal surgery - Bacterial
- Streptococcus, Pseudomonas,
Enterobacteriaceae, Staphylococcus
Infection/Inflammation of the cornea
Corneal leukoma
Keratitis Pathogenesis
- Corneal ulceration, stromal abscess
formation, surrounding corneal edema,
anterior segment inflammation - Corneal destruction complete in 24-48 hrs!
hypopyon
Leukocytic exudate
- can happen with keratitis when Outpouring of inflammatory cells into the
anterior chamber
Keratitis Clinical Presentation
- Reduced vision
- Sudden eye pain, severe
- Increased light sensitivity
- Tearing
- Excessive discharge from the eye
Keratitis
Diagnosis
- Cultures
- Scrapings
- Corneal biopsy
Keratitis management
- Antimicrobials
- Cycloplegic drops
- IV antibiotics
- Surgery
- Vitreoretinal specialist
Keratitis
Complications
- Corneal leukoma: Scar tissue formation with the presence of corneal vascularization necessitating corneal
- Irregular astigmatism: Uneven healing of the stroma → irregular astigmatism
- Corneal perforation: Most feared complication may result in endophthalmitis & eye loss, Corneal destruction complete in 24-48 hours
Most feared complication of keratitis
Corneal perforation
Ultraviolet (UV) Keratitis
Ultraviolet radiation injury to the eye
Ultraviolet (UV) Keratitis
Epidemiology/Etiology
- Most common cause of radiation injury to the eye
- Cornea absorbs most UV radiation
- Similar to a sunburn on dermal epithelium