Ochratoxicosis Flashcards

0
Q

most toxic mycotoxin in poultry is

A

ochratoxin

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1
Q

main difference between ochratoxicosis and alfatoxicosis

A

less common

more lethal

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2
Q

ochratoxin are produced by

A

penicillium veri-dicatum

aspergillus och-raceus

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3
Q

name ochratoxin is derieved from which speces

A

aspergillus ochraceus

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4
Q

ochratoxins are designated as ___,____,____,___

A

A
B
C
D

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5
Q

name the most common and most toxic ochratoxin among A,B,C,D

A

a

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6
Q

ducks are _____ times more sensitive to ochratoxin than chicken

A

7

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7
Q

pathogenesis of ochratoxin

A
  • inhibit protein synthesis
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8
Q

which organ is affected ochratoxin A

A

kidney

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9
Q

what does ochratoxin A do to kidney

A

PCT epithelium necrosis

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10
Q

main clinical signs of ochratoxicosis

A

same as alfatoxicosis

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11
Q

ppm and ochratoxicosis

A

0.6=immunosupression,anaemia,increase clotting time
2=loss of pigmentation,decreased egg production
4=death due to acute renal failure

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12
Q

main gross lesions in ochratoxicosis

A
  • paleness(L,P,K)

- urate deposits(L,K,S,H,pericardium)

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13
Q

main microscopic lesion in ochratoxicosis

A

-PCT epithelium necrosis + urate & proteinaceous casts

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14
Q

name the two genus causing Trichothecene mycotoxicosis

A
  • fusarium

- stachybotrys

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15
Q

there are about ___ related tricho-the-cene mycotoxins

A

80

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16
Q

trichothecene producing fungi produce this toxins at which temp.

A

beloe 20 C (winter)

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17
Q

name the 4 most common trichothecene toxins

A

T-2
HT-2
DAS
DON

18
Q

DAS stands for

A

di
acetyl
scirpenol

19
Q

DON

A

de
oxy
nivalenol

20
Q

main lesion of trichothecene mycotoxicosis

A

ulcers(dorsal surface of tongue,commisure of mouth,hard palate)

21
Q

name 7 other main mycotoxins(except alfa,ochra,tricho)

A

coffe mz

  • citrinin
  • oosporein
  • fumonisin
  • fusarochromanone
  • ergot
  • moniliformin
  • zearalenone
22
Q

name two nephrotoxic mycotoxins among coffe mz

A

citrinin

oosporein

23
Q

name a cardiotoxic mycotoxin

A

moniliformin

24
Q

name a mycotoxin which causes leg deformities

A

fusaro-chromanone

25
Q

name a mycotoxin causing vesicular dermatitis(sod disease)

A

ergot

26
Q

name a mycotoxin with oestrogenic activity

A

zear-alenone

27
Q

fusaro-chromanone is aka

A

TDP-1

28
Q

zear-alenone is aka

A

F-2

29
Q

TDP-1 is aka

A

fusar-chromanone

30
Q

F-2 is aka

A

zear-alenone

31
Q

citrinin is produced by

A

penicillium citrinum

32
Q

main effect of citrinin

A

water consumption increased
kidney swollen
wet dropping

33
Q

oosporein is produced by _____________

A

chaetomium trilaterale

34
Q

effect of oosporein on body

A

visceral and articular urate deposits

35
Q

fumonisin is produced by

A

fusarium moniliforme

36
Q

which fomonisin toxin is most common

A

B1

37
Q

name two diseases caused by fumonisin

A
  • equine leuko-encephalo-malacia

- porcine pulmonary oedema syndrome

38
Q

moniliformin is produced by

A

fusarium moniliforme

39
Q

fusarochromanone is produced by

A

fusarium sp.

40
Q

ergot is produced by

A

claviceps purpurea

41
Q

zearalenone is produced by

A

fusarium graminearum/gibberealla-zeae

42
Q

name mycotoxins produced by fusarium sp.

A

coFFe MZ

  • fumonisin
  • fusarochromanone
  • moniliformin
  • zearalenone