Obstruction/reflux Flashcards

1
Q

international reflux study committee grading of reflux

A

grade 1 reflux into ureter only
grade 2 reflux into renal pelvis
grade 3 mild dilatation of ureter and pc system
grade 4 - moderate dilatation, tortuous ureter, blunting fornices but papillary impression remain
grade 5 - severe dilataion, tortuous, loss of fornices and papillary impressions

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2
Q

incidence of PUV

A

1 in 4000

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3
Q

initial management of PUV

A

US on day 2 with creatinine – when creatinine not reflective of maternal
Then divide into two groups
Normal creatinine, passing urine, HUN mild – can give trimethoprim 2mg/kg orally at night, MCUG as OP, review result referral to local paed urology department
If plasma create raised, markedly abnormal US, not passing urine, trimethoprim 2mg/kg at night, catheterise urethral or SPC, monitor post ob diuresis can be up to 8-10/kg/hr
If abnormal creatinine measured bicarb as become acidotic and may require oral bicarb
Abnormal renal function involve paed nephrologist

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4
Q

initial management of PUV

A

US on day 2 with creatinine – when creatinine not reflective of maternal
Then divide into two groups
Normal creatinine, passing urine, HUN mild – can give trimethoprim 2mg/kg orally at night, MCUG as OP, review result referral to local paed urology department
If plasma create raised, markedly abnormal US, not passing urine, trimethoprim 2mg/kg at night, catheterise urethral or SPC, monitor post ob diuresis can be up to 8-10/kg/hr
If abnormal creatinine measured bicarb as become acidotic and may require oral bicarb
Abnormal renal function involve paed nephrologist
then MCUG
then cystoscopy and fulguration of valves
Repeat cystoscopy at 6 weeks to 3 months postop

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5
Q

4 types megaureter

A

reflux - VUR management
obstructing - conservative, stent +/- dilatation, refluxing implant, ureterostomy, reimplant
obstructing and refluxing - reimplant
non reflux non obstructive

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6
Q

definition mega ureter

A

> 7mm on 3rd trimester US

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7
Q

invesitgations megaureter

A

US check bladder
MCUG any reflux?
MAG3 - obstruction and differential function
cystoscopy and retrograde in selected cases

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8
Q

causes secondary megaureter

A

PUV, urinary stones, bladder dysfunction, ureterocele, ectopic ureter, diabetes insipidus

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9
Q

indications surgery in megaureter

how many require intervention

A
10-30%, usually in first 2 years life
majority need no intervention esp if below 10mm
give abx to all when born
impaired function DRF <40%
serial drop renal function
evidence increasing HN on US scans
infection episodes
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10
Q

surgery options megaureter

A

stent temporary with vuj dilatation +/- cutting can cure in 50% cases
then refluxing reimplant temporary, can do ureterostomy
then non refluxing reimplant - ureteroneocystotomy which will need end tapering
don;t forget circumcision if infections!

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11
Q

causes antenatal hydronephrosis based main post natal diagnosis

A
watson paper
50% non specific  dilatation
11% PUJO
12% VUR
6% MCDK
4% duplex ureterocele
2% VUJO
1% PUV
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12
Q

definition AN hydro

A

7 or more mm in third trimester UK NHS foetal anomaly screening
measured AP at renal hilum

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13
Q

SFU grading AN hydro

A

1= prominent pelvis
2 = dilated pelvis, some calyces visible
3 - dilated pelvis and calyces all seen
4= greater pelvic and calyceal dilatation, cortical thinning

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14
Q

who needs post natal ix of AN HN (4)

A

unilateral RPD >10mm at 32 weeks
bilateral RPD with APD >6mm at any gestational age
RPD in solitary kidney
RPD with ureteric dilatation

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15
Q

which AN will resolve

A

APD <12mm 98% will resolve stabilised or improved on FU

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16
Q

managment post natal HN

A

first scan between 48 hours and 4 weeks

OPD US in 2-6 weeks no prophylaxis, confirm measurement, decide if any further investigation

if 2cm need MAG 3 for drainage and function

bilateral dilatation need earlier US and MCUG (PUV) also check baby’s back
MAG3 with diurectic can be in a few months

17
Q

which AN HN are higher risk (5)

A
bladder abnormal
HN in solitary
bilateral severe HN
abnormal parenchyma
palpable kidney or bladder, poor stream
18
Q

indications for pyeloplasty(3)

A
split differential less than 40
serial function decline 10-15%
massive HN
flank mass
symptoms pain haematuriai UTI
19
Q

US features MCDK (3)

A

check CL kidney
higher incidence VUR (20%), PUJO, VUJO, dysplasia
cysts with wall in between, non communicating
atresia ureter/pelvis
no renal parenchyma

20
Q

natural history of MCDK

A

half will involute
same size 2-37%
enlarge 1-18%

21
Q

follow up of MCDK

A

us at 2 year, 5 years and 10 years
monitor hypertension, proteinuria
see if involutes with compensatory hypertrophy
DMSA confirm no function at 6-12 months

22
Q

how many AN HN is physiological or transient?

A

85%

23
Q

what is sig AN HN?

A

1-2 cm in third trimester

24
Q

monitoring of PUJO

A

until age 10, scan every 2 years

25
Q

PUJO and big palpable kidney

A

can do nephrostomy
check function MAG3 if borderline can do DMSA
can do nephrostogram confirm dx
can see if nephrostomy improves function
if 10% or more can do pyelplasty fuction may improve if MAG3 and DMSA confirm less than 10% function and normal CL kidney then nephrectomy

26
Q

sepsis with VUJO management

A
24-48 hours antibiotics
if doesn't settle
stent -difficult in small child
nephrostomy or cutaneous ureterostomy
alternative is a refluxing ureterostomy - side to end anastomosis just above VUJ
27
Q

sting vs HIT

A

STING inject 6 oclock into bladder mucosa
to lift up ureteric orifice as make mound
HIT - hydrodistension with scope into distal ureter and inject into wall of distal ureter

28
Q

whittaker test

A
nephrostomy and catheter in bladder
saline with contrast at 10ml/min
pressure in kidneyu and bladder
if <15cm water then system not obstructed 
if more than 22 then obstructed
15-22 are equivocal
29
Q

Dhillon GOSH natural history study

A

17% need surgery
56% stable
27% resolved

gross HN
AP diameter more than 5cm treatd
20-50mm not clear cut

> 30m, 55% will be treated

30
Q

post operative pyeloplasty procedure

A

twoc next day
clamp 48 hours
nephro stent removed 7 days