Obstetrics Flashcards
What is the average length of a normal pregnancy?
37-42w
What does gravidity and parity mean?
Gravidity: total number of pregnancies
Parity: total number of pregnancies >24w
What are the normal changes in pregnancy (cardiac)? (3)
Increase in cardiac output due to Increase in SV and HR BP first drops then rises Slight cardiomegaly Decrease in peripheral resistance Ejection systolic murmur Compression of IVC
What are the normal changes in pregnancy (blood)? (2)
Dilutional anaemia: increase in plasma volume, decrease in Hb
Decreased albumin
Increased fibrinogen and clotting factors
What are the normal changes in pregnancy (resp)? (3)
Increased tidal volume
Increased minute ventilation- but no increased RR
Some SOB
What are the normal changes in pregnancy (endo)? (3)
Increased thyroid size and parathyroid
Increased basal metabolic rate
Increased prolactin through
What are the normal changes in pregnancy (uterus)? (2)
Increased uterus size
Braxton Hick contractions
What are the normal changes in pregnancy (gastro)? (3)
Constipation and haemorrhoids- due to reduced gastric emptying
GI reflux
Nausea and vomiting
Increased renal blood flow and GFR
In normal pregnancy: what effects does the increased oestrogen production have on the breast and vagina? (3)
Increase in breast and nipple size
Vaginal hypertrophy
Increased discharge
At what dates should the booking visit occur and what is done in it?
Before 12w- ideally 10w
FBC, blood group, HIV, serology for syphillis (VDRL), Hep B, rubella
What supplement do pregnant women need to take and for how long for and what dose?
Folic acid from pre-conception to 12w gestation
Low risk: 0.5mg
High risk: 5mg (DM, obesity, PMH of spina bifida)
When is the main ultrasound scan and what does it look for?
11-13+6 looking for:
- Dating: using crown rump length - estimate gestational age
- Nuchal translucency - for chromosomal abnormalities + beta-HCG, PAPP-A (pregnancy associated plasma protein A) (combined test)
- Viability of the pregnancy
- Presence of multiple pregancies
What is involved in the combined and quadruple tests that can be offered to screen for chromosomal abnormalities e.g. Down’s, Patau’s, Edwards and at what times?
Combined test: between 11 + 13+6: NT + beta HCG + PAPP-A
Quadruple test if they have missed combined test at 18-20 weeks (2nd trimester): AFP + unconjugated estriol + inhibin A +beta HCG
If the combined test is positive/baby is high risk for or chromosomal abnormalities e.g. Down’s, Patau’s, Edwards, what further two tests can be offered and when?
Chorionic villus sampling at 11-14w: safer than amnio
Amniocentesis at 15- 20w: risk of miscarriage, infection, pre-term labour
What is the scan at 18-20 weeks looking at?
Anomaly scan: looking for foetal abnormalities like spina bifida or anencephaly.
Rhesus haemolytic disease has occurred in this women’s pregnancy. Is she rhesus + or - and is the foetus rhesus + or -?
Foetus: rhesus + (DD/Dd)
Mother: rhesus - (dd)
Mother creates anti-D antibodies to foetus which cross placenta and destroy foetal RBCs (haemolytic anaemia )
How can you prevent rhesus haemolytic disease from occurring?
Give anti-D to rhesus -ve mothers at 28w
What are some maternal complications of multiple pregnancy? (3)
Polyhydramnios Pre-eclampsia APH and PPH Instrumental delivery Anaemia- increased iron and folate requirements Gestational Diabetes Placental abruption
What are some foetal complications of multiple pregnancy? (3)
Foetal mortality
Growth restriction
Prematurity
Malformations
What is the risk in monochorionic twins?
They share placenta: risk of foeti-foetal transfusion: blood flow doesn’t flow evenly between them
What is the cause of polyhydramnios and what are some risk factors?
Due to increased foetal urination and decreased foetal swallowing
RF: multiple pregnancy, trisomy 18 & 21, diabetes, oesophageal atresia of foetus
How is polyhydramnios treated?
Serial ultrasounds
Maternal steroids
May consider indomethacin or drainage
What is the definition of small for gestational age and what are some risk factors (3)?
Symphysial fundal height <10th gentile for their gestational age. RF: maternal smoking, multiple pregnancy, maternal age >40, pre-eclampsia, previous SGA baby
What are some risks of SGA baby?
Prematurity, foetal distress and meconium aspiration, foetal mortality (hypoxia), cerebral palsy