Obstetrics Flashcards

1
Q

What is the average length of a normal pregnancy?

A

37-42w

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What does gravidity and parity mean?

A

Gravidity: total number of pregnancies
Parity: total number of pregnancies >24w

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the normal changes in pregnancy (cardiac)? (3)

A
Increase in cardiac output due to Increase in SV and HR 
BP first drops then rises
Slight cardiomegaly 
Decrease in peripheral resistance
Ejection systolic murmur 
Compression of IVC
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the normal changes in pregnancy (blood)? (2)

A

Dilutional anaemia: increase in plasma volume, decrease in Hb
Decreased albumin
Increased fibrinogen and clotting factors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the normal changes in pregnancy (resp)? (3)

A

Increased tidal volume
Increased minute ventilation- but no increased RR
Some SOB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the normal changes in pregnancy (endo)? (3)

A

Increased thyroid size and parathyroid
Increased basal metabolic rate
Increased prolactin through

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the normal changes in pregnancy (uterus)? (2)

A

Increased uterus size

Braxton Hick contractions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the normal changes in pregnancy (gastro)? (3)

A

Constipation and haemorrhoids- due to reduced gastric emptying
GI reflux
Nausea and vomiting
Increased renal blood flow and GFR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

In normal pregnancy: what effects does the increased oestrogen production have on the breast and vagina? (3)

A

Increase in breast and nipple size
Vaginal hypertrophy
Increased discharge

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

At what dates should the booking visit occur and what is done in it?

A

Before 12w- ideally 10w

FBC, blood group, HIV, serology for syphillis (VDRL), Hep B, rubella

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What supplement do pregnant women need to take and for how long for and what dose?

A

Folic acid from pre-conception to 12w gestation
Low risk: 0.5mg
High risk: 5mg (DM, obesity, PMH of spina bifida)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

When is the main ultrasound scan and what does it look for?

A

11-13+6 looking for:

  • Dating: using crown rump length - estimate gestational age
  • Nuchal translucency - for chromosomal abnormalities + beta-HCG, PAPP-A (pregnancy associated plasma protein A) (combined test)
  • Viability of the pregnancy
  • Presence of multiple pregancies
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is involved in the combined and quadruple tests that can be offered to screen for chromosomal abnormalities e.g. Down’s, Patau’s, Edwards and at what times?

A

Combined test: between 11 + 13+6: NT + beta HCG + PAPP-A
Quadruple test if they have missed combined test at 18-20 weeks (2nd trimester): AFP + unconjugated estriol + inhibin A +beta HCG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

If the combined test is positive/baby is high risk for or chromosomal abnormalities e.g. Down’s, Patau’s, Edwards, what further two tests can be offered and when?

A

Chorionic villus sampling at 11-14w: safer than amnio

Amniocentesis at 15- 20w: risk of miscarriage, infection, pre-term labour

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the scan at 18-20 weeks looking at?

A

Anomaly scan: looking for foetal abnormalities like spina bifida or anencephaly.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Rhesus haemolytic disease has occurred in this women’s pregnancy. Is she rhesus + or - and is the foetus rhesus + or -?

A

Foetus: rhesus + (DD/Dd)
Mother: rhesus - (dd)
Mother creates anti-D antibodies to foetus which cross placenta and destroy foetal RBCs (haemolytic anaemia )

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

How can you prevent rhesus haemolytic disease from occurring?

A

Give anti-D to rhesus -ve mothers at 28w

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What are some maternal complications of multiple pregnancy? (3)

A
Polyhydramnios
Pre-eclampsia
APH and PPH 
Instrumental delivery
Anaemia- increased iron and folate requirements
Gestational Diabetes 
Placental abruption
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What are some foetal complications of multiple pregnancy? (3)

A

Foetal mortality
Growth restriction
Prematurity
Malformations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What is the risk in monochorionic twins?

A

They share placenta: risk of foeti-foetal transfusion: blood flow doesn’t flow evenly between them

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What is the cause of polyhydramnios and what are some risk factors?

A

Due to increased foetal urination and decreased foetal swallowing
RF: multiple pregnancy, trisomy 18 & 21, diabetes, oesophageal atresia of foetus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

How is polyhydramnios treated?

A

Serial ultrasounds
Maternal steroids
May consider indomethacin or drainage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What is the definition of small for gestational age and what are some risk factors (3)?

A

Symphysial fundal height <10th gentile for their gestational age. RF: maternal smoking, multiple pregnancy, maternal age >40, pre-eclampsia, previous SGA baby

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

What are some risks of SGA baby?

A

Prematurity, foetal distress and meconium aspiration, foetal mortality (hypoxia), cerebral palsy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

What is the definition of intrauterine growth restriction and what are some risk factors? (3)?

A

IUGR: estimated foetal weight <10th centile - slow growth.
RF: maternal smoking, alcohol & drugs, pre-eclampsia, maternal conditions eg. renal failure, IBD, CF, asthma , multiple pregnancy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

What investigations are done in a foetus with IUGR?

A
Serial abdo circumference- SFH
Serial Ultrasound scans 
CTG - assessment of cardiac oxygenation 
Amniotic fluid index 
Regular umbilical artery doppler- if reversed/absent end diastolic flow = may need C-section and steroids
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

What is the definition of small for dates?

A

Foetus with birth weight <10th centile on customised growth charts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

What is the definition of large for dates and how is it measured?

A

Weight >90th gentile on customised growth chats

Measure with SFH and serial US

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

What is the main risk factor for large for dates/foetal macrosmia and what is the main complication?

A

Gestational diabetes , polhydramnios

Risk of shoulder dystocia- may need C section if baby >4.5kg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Heather is a 30 year old woman. She is currently experiencing lower abdominal pain and vaginal bleeding. Her last period was 14 weeks ago, and she had a positive pregnancy test 12 weeks ago. What is the diagnosis?

A

Miscarriage: loss of pregnancy <24w

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

What are the features of a threatened miscarriage? Is cervical os open or closed?

A

Mild painless bleeding, cervical os closed. 75% settle themselves.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

What are the features of a inveitable miscarriage? Is cervical os open or closed?

A

About to miscarry- either after threatened or by itself. Heavier bleeding with clots. Cervical os is OPEN.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

What are the features of a incomplete miscarriage? Is cervical os open or closed?

A

Most POC passed, some left in uterus. Cervical os is open. May need dilation and curettage.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

What are the features of a complete miscarriage? Is cervical os open or closed?

A

All POC passed, US: empty cavity. May be bleeding and labour like cramps. cervical os is closed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

What are the features of a missed miscarriage? Is cervical os open or closed?

A

Foetus has died but remains in uterus. TVUS: foetal pole large and no foetal heart activity. May have had a past bleed. Cervical os is closed.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

What are the features of a septic miscarriage?

A

Infected contents of uterus- painful uterus, peritonism signs (swelling abdo, pain).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

Heather is a 30 year old woman. She is currently experiencing lower abdominal pain and vaginal bleeding. Her last period was 14 weeks ago, and she had a positive pregnancy test 10 weeks ago.
Heather’s cervix is open and she is having an inevitable miscarriage.
Obs: BP 90/58, HR 105, RR 20, Temp: 36.9

What is your initial management?

A

ABCDE

Profuse bleeding: IM ergometrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

What are the options for treatment of a miscarriage?

A

Expectant: wait 7-14 days for miscarriage to complete itself.
Medical management: if expectant doesn’t work/pt preference: vaginal misoprostol
Surgical: suction/theatre if heavy bleeding, infection, severe pain. Give anti-D

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

Katrina was diagnosed with endometriosis. She underwent laparoscopy with surgical ablation and now takes ibuprofen for pain.
A year later, she presents to A&E with abdominal pain and some vaginal bleeding. She has vomited a few times. She is sexually active and her last period was 8 weeks ago.
What is the diagnosis?

A

Ectopic pregnancy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

What is the most common site for implantation in ectopic pregnancy?

A

Ampulla of Fallopian tube

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

What are some risk factors for ectopic pregnancy?

A

PID, previous ectopic, endometriosis, surgery to tubes eg. tubal ligation, IVF, smoking

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

What are the symptoms of ectopic pregnancy?

A

Abdo pain- unilateral (LIF), colicky then constant
Dark PV bleeding
N&V
Syncope
Shoulder tip pain - bleeding irritates phrenic nerve

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

What are some signs of ectopic pregnancy?

A

Cervical excitation
Pelvic tenderness
Hypotension , tachycardia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

Katrina was diagnosed with endometriosis. She underwent laparoscopy with surgical ablation and now takes ibuprofen for pain.
A year later, she presents to A&E with abdominal pain and some vaginal bleeding. She has vomited a few times. She is sexually active and her last period was 8 weeks ago.

What investigations might you do?

A

Bloods- FBC, U&E, group and save, beta HCG (high)
Pregnancy test
TVUS - no intrauterine pregnancy

this is an ectopic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
45
Q

What are the options for treatment of ectopic pregnancy?

A

Expectant: mild symptoms, beta-HCG is low and falling. Do serial beta HCGs
Medical: methotrexate 1 dose. CI: live ectopic.
Surgical: symptoms, very high beta HCG. Laprascopic salpingectomy if other tube is healthy or salpingotomy if other tube is not healthy/retain fertility

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
46
Q

What are some risk factors for hyperemesis gravidarum

A

RF: multiple pregnancy, molar pregnancy, previous hyperemesis gravidarum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
47
Q

A pregnant lady in her 14th week gestation presents complaining of severe nausea and vomiting. She says its been getting so bad she’s unable to eat or drink anything at all. She says she’s tried eating small amounts and tried having ginger but nothing has helped. She also describes feeling dizzy. On examination- she has dry mucous membranes, is hypotensive and has reduced skin turgor. How are you going to manage this?

A

Hospital admission for IV fluids - normal saline with potassium or hartmann’s
Anti-emetics- promethazine/cyclizine
Thiamine replacement IV in hospital

This is hyperemesis gravid arum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
48
Q

What are the two types of gestational trophoblastic disease?

A

Molar pregnancy

Choriocarcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
49
Q

What happens in a molar pregnancy?

A

Abnormal fertilised egg implants in uterus. The cells proliferate without control and take over–> instead of foetus, get a mass of abnormal cells (trophoblast) which produce beta hCG as derived from chorion.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
50
Q

How do you investigate (what would you see) and treat molar pregnancy?

A

beta- HCG raised and US- snowstorm appearance of swollen villi and moles
Tissue is removed with gentle suction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
51
Q

How do you diagnose pre-eclampsia?

A

HTN: BP >140/90
Proteinuria: 0.3g/24h

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
52
Q

What are some risk factors for pre-eclampsia?

A

Diabetes, previous pre-eclampsia, previous HTN, renal disease eg. CKD, FMH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
53
Q

What investigations do you want to do in a patient with pre-eclampsia?

A

Dipstick for proteinuria
FBC, U&E, LFTs, clotting
TVUS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
54
Q

How do you treat pre-eclampsia (mild, moderate, severe)?

A

Mild: regular blood tests- FBC, U&E, LFTs, foetal scans , regular BP
Moderate: treat if BP >150/100= labetalol
Severe: labetalol (2nd line=nifedipine), Mg sulphate as prophylaxis for pre-eclampsia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
55
Q

What can you give to patients with a high risk of pre-eclampsia eg. past history/FMH?

A

Aspirin from 12s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
56
Q

A lady comes in with known pre-eclampsia and has been monitored throughout with regular blood tests and blood pressure checks. Today she has come to A&E as she’s got a very bad headache, feels drowsy, her vision has blurred and she’s had 2 seizures where she has fallen to floor and her arms have gone stiff and shook. What’s happened and how are you going to treat?

A

Eclampsia

Magnesium sulfate IV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
57
Q

What does HELLP syndrome stand for and when does it occur?

A

Complication of pre-eclampsia
Haemolysis + elevated liver enzymes + low platelets
causes RUQ pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
58
Q

How do you treat HELLP syndrome?

A

Deliver if >34 weeks

Tranfuse Hb, platelets , FFP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
59
Q

What are the cut offs for gestational hypertension diagnosis? and how to treat?

A

BP >140/90

lifestyle, if need meds: oral labetalol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
60
Q

What tests can be done to diagnose gestational diabetes?

A

Random fasting glucose >7

2 hour OGTT at 28w (if RF)= >8.5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
61
Q

What are some risk factors for gestational diabetes? What test will you do for those with risk factors?

A
FMH of GD
Previous GD in prev pregancy
Increased BMI 
Ethnicity -SA, carribean 
increasing age 

OGTT at 28weeks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
62
Q

What are some foetal complications of gestational diabetes?

A

Macrosomia
Shoulder dystocia
Congenital abnormalities e.g.neural tube and cardiac
Post natal: hypoglycaemia (baby is accustomed to hyperglycaemia), jaundice

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
63
Q

What are some maternal complications of gestational diabetes?

A
Pre-eclampsia (and risk of HELLP)
Birth trauma and instrumental delivery
Hypoglycaemia
Retinopathy
Post natal: increased risk of T2DM, hypoglycaemia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
64
Q

A pregnancy lady has an OGTT at 28 weeks due to having previous gestational diabetes in her last pregnancy. Her value comes back at 9 and her fasting plasma glucose is 7.5mmol/L. Foetal US has shown the baby to have a large head. What treatment are you going to offer?

A

Start insulin straight away as OGTT >8.5 and fasting plasma glucose >7 with foetal macrosmia.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
65
Q

What are the options for treatment of gestational diabetes?

A

First line: lifestyle- diet, exercise, weight loss
If >2 weeks and no change: insulin
Metformin only if CI to insulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
66
Q

What are the TORCH infections?

A

Infections of foetus - toxoplasmosis, other- syphillis, varicella zoster, parvovirus B19, rubella, CMV and herpes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
67
Q

What complications to the foetus occur with CMV infection?

A

IGUR, hydrocephalus, motor and sensory impairment, deafness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
68
Q

How do you prevent herpes zoster infection travelling from mother to neonate?

A

Give baby varicella immune immunoglobulin (VIZG) at birth. C-section if within 6 weeks of onset.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
69
Q

What complications to the foetus occur with rubella infection?

A

Cataracts, deafness, cardiac disease, low IQ

70
Q

How do you treat syphillis infection in mother/neonate?

A

IM Benzylpenicillin

71
Q

What symptoms occur with toxoplasmosis infection?

A

Rash + sore throat + fever

72
Q

How is vertical transmission of group B strep prevented in labour?

A

IV benzylpenicillin in labour

73
Q

What are risk factors for group B strep sepsis? (2)

A

Prolonged rupture of membranes
Prematurity
Previous Group B strep infection

74
Q

What foods can lead to listeria infection?

A

Soft cheeses, milk, pate

75
Q

What foetal signs may occur with listeria infection?

A

respiratory distress, convulsions, premature labour

76
Q

What are the signs of measles in neonate?

A

Generalised erythematous maculopapular rash, Koplik spots, conjunctivitis, cough

77
Q

Can HIV positive mothers breastfeed?

A

No

78
Q

What treatment should be started in a HIV positive mother?

A

HAART- highly active retroviral therapy from 28w till labour

79
Q

Can a HIV positive mother have normal labour?

A

If viral load is <50 copies : yes

If viral load >50: elective C section

80
Q

What can be given to a newborn with a HIV positive mother?

A

Zidovudine or HAART

81
Q

A pregnant lady comes in complaining of new onset calf pain. It started this morning in her left calf and has been getting worse. On examination the left calf looks red, hot, swollen and tender on palpation. She has no shortness of breath and chest pain at present. How will you investigate and treat?

A
DVT 
Bloods: FBC, U&E, LFTs, clotting
D-dimer 
Imaging: Duplex US scan of left leg 
Treatment: LMWH eg. enoxaparin or dalteparin
82
Q

A pregnant lady comes in complaining of new onset SOB and chest pain worse on breathing in. She also has noticed a new cough and has coughed up blood once. She has no leg tenderness or swelling of the legs at present. How will you investigate and treat?

A
PE 
Bloods: FBC, U&E, LFTs, clotting
D-dimer
Imaging: 1. CXR, 2. VQ scan/ CTPA 
Treatment: LMWH eg. enoxaparin or dalteparin
83
Q

How long will you continue LMWH treatment in pregnancy for DVT/PE

A

Through pregnancy, stop it for labour and re-start after or change to warfarin after

84
Q

What are the complications of uncontrolled severe asthma in a pregnant woman?

A

Preterm labour

Foetal growth restriction

85
Q

An indian origin pregnant woman comes to antenatal clinic with a worsening cough. She says its been ongoing for 6 weeks and has noticed herself coughing up blood a couple of times. She thinks she may have lost some weight even though she’s been eating ok and is waking up in the night sweating frequently. What investigations are you going to do given the diagnosis?

A
TB: 
Mantoux test (tuberculin skin test)
Sputum culture for acid fast bacilli (ZN stain)
Interferon gamma
CXR
86
Q

How do you treat TB?

A

Rifampicin
Isoniazid
Pyrazinamide
Ethambutol
+ Pyridoxine (reduce risk of peripheral neuropathy with isoniazid)
2 months all of them, 4 months just rifampin and isoniazid

87
Q

A pregnant lady comes into clinic complaining of going to the toilet more often than usual. She has also noticed some burning on urination and this is not normal for her. She feels well otherwise and her obs are stable, What investigations are you going to do and how will you treat?

A

Bedside: urine dipstick- leukocytes and protein, MSU send for MC&S
Bloods: FBC, U&Es!- creatinine, LFTs
Tx: nitrofurantoin (unless at term - then cefalexin)

88
Q

A pregnant lady comes into clinic complaining of going to the toilet more often than usual. She has also noticed some burning on urination and this is not normal for her. She also is complaining of some pain in her abdomen that goes round to the back and has felt quite feverish later. On examination she is tachycardic and looks sweaty. What investigations are you going to do and how will you treat?

A
Admit - unwell. 
Bedside: urine dipstick, MSU for MC&S
Bloods: FBC, U&Es- creatinine, eGFR, blood cultures
Imaging: may do renal US 
Abx: IV cefuroxime
89
Q

Can anti-epileptic drugs be continued in pregnancy and labour?

A

Not sodium valporate
Can continue carbemazepine and lamotrigine at lowest dose possible in preg and labour and post partum- increase back to usual dose

90
Q

Why does obstetric cholestasis occur?

A

increased oestrogen reduce bile salt uptake by hepatocytes

91
Q

What symptoms and what would you find on blood tests in a patient with obstetric cholestasis?

A
Intense pruritus (no rash) worse at night
Bloods: FBC, U&E, clotting, LFTs- cholestatic picture (ALP >ALT raised), raised bilirubin
92
Q

How do you treat obstetric cholestasis?

A

Vitamin K
Ursodeoxycholic acid for itching
induce labour at 37-38w

93
Q

What scale can be used to assess a patient for post-natal depression?

A

Edinburgh post natal depression scale

94
Q

How do you treat post-natal depression?

A

CBT and interpersonal therapy

If symptoms persist: sertraline

95
Q

How do you treat post partum psychosis?

A

Need admission to hospital for specialist input
Therapy , reassurance
Antipsychotics- 2nd generation eg. risperidone and antidepressants

96
Q

A pregnant lady of 26 weeks gestation has come in with vaginal bleeding to A&E. Her bleeding started an hour ago and has not stopped and is very heavy. How are you initially going to manage her?

A

ABCDE
Full set of observations
Cannulate- large bore, IV fluids, bloods- FBC, U&E, clotting, group and save
Consider ergometrine if bleeding heavy
Examination for cause eg. abdominal
TVUS eg. if cause is placenta praevia/abruption and then vaginal exam
CTG

97
Q

Why do you never perform vaginal exam in patients with heavy PV bleeding after 24w?

A

If placenta praevia- it will cause massive bleeding! Need TVUS first

98
Q

A 43 year old pregnant lady of 26 weeks gestation has come to A&E presenting with painless intermittent PV bleeding. She has no abdominal pain and denies any other symptoms at all. Her recent scan with the midwifes show her baby to be in a breech position. What is the likely diagnosis?

A

Placenta praevia- intermittent painless PV bleeding + abnormal lie of baby
RF: maternal age >40, prev C-section, multiparity, multiple pregnancy

99
Q

What is the difference between major placenta praevia and minor?

A

Major: placenta is impacted in lower segment of uterus covering os
Minor : placenta impacted in lower segment of uterus NEAR os

100
Q

What are some complications of placenta praaevia?

A

Major haemorrhage that can continue post partum
Transverse lie
Operational delivery/labour complications
Placenta accreta esp if prev C-section (placenta adheres to uterus)

101
Q

After initial A-E assessment, how do you treat placenta praaevia? (delivery)

A

C-section if major

Try for normal delivery with minor unless placenta impacted within 2cm of os

102
Q

A pregnant lady of 26 weeks gestation comes in complaining of painful vaginal bleeding. It started this morning and hasn’t stopped and is accompanied by abdominal pain. You do an abdominal examination and the uterus feels ‘woody and hard’. Her obs show her to have a very low BP and very high RR and HR. Given the likely diagnosis, what is your initial management going to be?

A
Placental abruption 
Management:
-Admit
-ABCDE
- Cannula- large bore, IVF
- Bloods- FBC, U&E, clotting, cross match
-Blood transfusion 
- Analgesia 
- Catheterise 
-TVUS!! 
-Foetal CTG
103
Q

How would you decide whether a patient with placental abruption needs C-section or not?

A

Based on foetal distress: if foetal distress -C section. If not but >37w= induce with amniotomy.

104
Q

What is the main complication with placental abruption in mother?

A

DIC !

105
Q

What is vasa praevia and how does it cause foetal haemorrhage?

A

vasa praevia is when a foetal blood vessel runs in the membranes before presenting part and umbilical cord attaches to these membranes
Wen membranes rupture in labour, this foetal blood vessel ruptures causing foetal haemorrhage

106
Q

A 26 week gestation pregnant woman has PV bleeding which is painless. When you ask her when it started she says it only started as soon as her water broke. CTG shows some foetal bradycardia but the mother is stable and well. What is the likely diagnosis?

A

Ruptured vasa praevia - painless PV bleeding at ROM (spontaneous- water breaking or amniotomy)

107
Q

How do you treat ruptured vasa praevia ?

A

C-section

108
Q

What occurs in placenta accreta, increta and percreta and how are they treated if diagnose before birth?

A

Accreta: abnormal adherence of placenta to uterus
Increta: infiltration of myometrium
Percreta: infiltration through uterus into other structures eg. bowel/ bladder
Tx is with C-section and hysterectomy if diagnosed before birth on USS

109
Q

What happens in the first stage of labour?

A

Latent: cervix dilates 0-3cm. Irregular contractions every 5-10mins
Active: cervix dilates 3-10cm (full dilation) at 1cm per hour. Regular contractions.

110
Q

What happens in the 2nd stage of labour?

A

Lasts from full cervical dilation to birth
Get descent, flexion and internal rotation as well as extension- can see head
Passive: head reaches pelvic floor, woman has uncontrollable desire to push.
Active: mother is pushing

111
Q

What happens in 3rd stage of labour?

A

Delivery of the placenta.

Active management here: oxytocin, early cord clamping and controlled cord traction to reduce PPH risk

112
Q

What are the 7 steps the foetus goes through to be delivered?

A
Engagement as head enters pelvis
Descent
Flexion - for easy passage into pelvis
Internal rotation - head rotates in 90 degrees so face faces sacrum 
Extension
External rotation/restitution 
Expulsion
113
Q

What are some indications for induction of labour?

A

Prolonged pregnancy- 12 days post due date
Baby growth problems eg. IUGR, APH
Maternal medication conditions e.g. pre-eclampsia, gestational diabetes

114
Q

What are some contraindications for induction of labour?

A

Malpresenation

Foetal distress

115
Q

What score can be used to decide if induction of labour is needed? What value is the cut off?

A

Bishop’s score

Score <5= labour is unlikely to progress on it’s own and likely needs induction

116
Q

What are the options for induction of labour?

A

Membrane sweep
1. Vaginal prostaglandin gel/pessary - max 2 doses
2. Amniotomy (ARM) +/-oxytocin (start 2 hours after if no success with amniotomy)
Can use oxytocin alone if SROM

117
Q

What are some complications of induction of labour?

A
Infection 
Foetal distress
Increased risk of instrumental delivery/CS
Prematurity 
PPH
118
Q

What are some side effects/complications from using an epidural in labour?

A
Longer labour 
Increased risk of instrumental delivery 
Loss of bladder control 
HYPOTENSION 
Foetal tachycardia
119
Q

What are some risk factors for abnormal foetal presentations?

A
Prematurity 
Large baby 
Uterine problems eg. fibroids 
Maternal smoking 
Multiple pregnancy 
Polhydramnios/oligohydramios 
2nd baby
120
Q

A 28 week gestation pregnant woman comes to clinic and a foetal US has shown her baby is breech. What do you tell her?

A

Just to wait and see until 36w- it might turn by itself

121
Q

A 38 week gestation pregnant woman comes to clinic and a foetal US has shown her baby is breech. What do you do?

A

External cephalic version- try and turn the breech if waters broken.
If this doesn’t work: C-section or vaginal delivery- but increased risk of birth trauma

122
Q

What is an occiput-posterior foetal malpresentation ? and how might you treat?

A

Baby is back to back so can’t feel it’s back

Tx: rotational forceps to OA

123
Q

What is an occiput-transverse foetal malpresentation? What can you feel? And how might you treat it?

A

Foetal head is lying on side - can palpate the sutures and fontanelle
Tx: ventouse to rotate

124
Q

What happens in a brow presentation? What can you feel? How do you treat?

A

Full extension or flexion of neck (usually chin tucked, neck slightly extended). Can feel anterior fontanelle, supraorbital ridge and nose. C-section

125
Q

What happens in a face presentation? What can you feel? How do you treat?

A

Full extension of neck. Mouth, nose and eyes are palpable. Likely need C-section.

126
Q

What are some indications for instrumental delivery?

A
Prolonged 2nd stage
Maternal exhaustion  
Maternal conditions preventing proper pushing eg. cardiac , paraplegia 
Suspected foetal distress
Breech delivery
127
Q

What are the complications of forceps delivery?

A

Maternal mainly- genital tract trauma eg. vaginal tears. Can get rotational or non-rotational forceps.

128
Q

What are the complications of ventouse delivery?

A

Foetal mainly eg. chignon - little swelling on scalp that should disappear, cephalohaemoatoma , retinal haemorrahges

129
Q

What are some indications for C-section?

A
Previous vertical C-section
Foetal compromise eg. cord prolapse 
Prolonged labour 
Malpresentation
Pelvic deformity
130
Q

What type of breech presentation is most common and which type is most associated with cord prolapse?

A

Extended: hips flexed, knees extended. most common.

Footling- legs underneath bum - one leg hangs down. cord prolapse

131
Q

Which type of C-section is associated with less bleeding and adhesions? lower segment CS or classic SC?

A

LSCS- transverse incision

Classic - only if huge fibroids/extreme prematurity.

132
Q

A woman has just given birth to a lovely baby boy. The boy is fit and healthy and she will be taken to recovery once the placenta has been delivered. However it’s been 80 mins now and the placenta has yet to be delivered. What are you going to do?

A

Retained placenta is an emergency!

Treat with IM syntocinin to stimulate uterine contractions. Or manually remove it.

133
Q

What is the most common cause of retained placenta?

A

Uterine atony

134
Q

A woman in her 35th week gestation (3rd trimester) presents to A&E with severe abdominal pain and PV bleeding. She is tachycardic and hypotensive. CTG is showing foetal distress. You find out her last 3 children were C-sections. What could be the diagnosis?

A

Uterine rupture!

135
Q

What is the most common cause of uterine rupture?

A

Due to dehiscence of C-section scar–> maternal haemorrhage and foetal distress as it is forced out the rupture

136
Q

How do you treat uterine rupture?

A
ABCDE
IV fluids
O2
Analgesia
Bloods- FBC, U&E, clotting, cross match
Transfuse
DELIVER BABY= C-Section 
If rupture is small - repair 
If big - in cervix/vagina= hysterectomy
137
Q

What happens in cord prolapse?

A

Cord descends below the presenting part –> vasospasms–>foetal hypoxia –> damage (Cerebral palsy) or death

138
Q

What are risk factors for cord prolapse?

A

Anything that stops engagement of head:

  • Prematurity
  • Breech
  • Abnormal foetal lie
  • Polyhydramnios
  • Praevia
  • Second twin
139
Q

How do you manage cord prolapse definitively? And what can you do to manage to vasospasm of cord?

A

Usually need C-section or instrumental vaginal delivery (only if fully dilated at 10cm)
If cord is below level of Introits: push it back in with finger
If above: leave it alone
Give terbutaline or nifedipine - reduces contractions

140
Q

What are some complications of shoulder dystocia- foetal and maternal?

A

Foetal: hypoxia and asyphxia, Erb’s palsy C5, C6, C7–> waiter’s tip presentation, hypoxic ischaemic encephalopathy ,fractured clavicle
Maternal: bladder/ureter rupture, PPH, perineal tears

141
Q

How would you manage shoulder dystocia?

A

McRoberts manœuvre to increase angle of pelvis, apply suprapubic pressure to try displace shoulder.
If fails: episiotomy + internal manoeuvres eg. Woodscrew manoevouer

142
Q

Uterine inversion is a rare obstetric emergency where the uterus fundus collapses into the endometrial cavity turning it inside out. If you did see it- how might the mother present and how would you treat?

A

Mother presents with shock and haemorrahge

Tx: 1. push fundus up manually with terbutaline to relax the uterus. 2. infuse warm saline into the vagina.

143
Q

What happens in amniotic fluid embolism?

A

A rare birth complication where foetal cells/amniotic fluid enter mother’s blood stream and there is an anaphylaxis reaction to it

144
Q

How does a patient present with an amniotic fluid embolism?

A

Maternal chest pain, SOB, resiratory distress, tachycardia, hypoxia, palpitations

145
Q

How do you treat an amniotic fluid embolism?

A
ABCDE
Oxygen 
IV fluids 
Analgesia
Bloods- FBC, U&E, clotting, cross match
Correct clotting abnormalities - get DIC picture so need FFP/blood 
DELIVERY OF BABY - C/S
146
Q

Before what week is a baby classed as premature and what complications are associated with prematurity?

A

<37w
Associated: developmental delay, cerebral palsy, visual problems, infections of placenta/cord, infections of foetus, genital infections eg. UTI of mum

147
Q

What tests can be done to predict risk of prematurity?

A

Foetal fibronectin test- if found in vaginal fluid- likely premature

148
Q

What treatment can be offered to help reduce complications associated with prematurity?

A

IV benzyl penicillin - reduce risk of infection

Steroids eg. betamethasone and nifedipine- reduce risk of RDS

149
Q

After what week is baby classed as ‘postmature’ and what complications are associated with post-maturity?

A

> 42w
Associated: neonatal death, instrumental delivery, foetal distress, maternal death, placental insufficient, meconium aspiration syndrome

150
Q

How do you manage post-maturity?

A

Induction! - membrane sweep, prostaglandin gel/pessary, oxytocin if SROM, amniotomy +/-oxytocin

151
Q

What are the two methods of foetal monitoring?

A

Intermittent asuculatiation via US doppler

CTG continuous monitoring

152
Q

What does the Dr stand for in Dr C Brvado in CTG foetal monitoring?

A

Dr- define Risk factors eg. prematurity, post-maturity, induction , C-section, pre-eclampsia

153
Q

What does the C stand for in Dr C Brvado in CTG foetal monitoring?

A

Contractions- Hyperstimulation is over 5 contractions in 10 mins

154
Q

What does the Br stand for in Dr C Brvado in CTG foetal monitoring?

A

Baseline rate: normal is 100-160
Bradycardic: <100 associated with hypoxia
Tachycardia >160- associated with maternal pyrexia, hypoxia

155
Q

What does the V stand for in Dr C Brvado in CTG foetal monitoring?

A

Variation. Decreased variations (<5bpm): foetal hypoxia (>40min of decreased variability), foetus sleeping (<40 min of decreased variation).

156
Q

What does the A stand for in Dr C Brvado in CTG foetal monitoring?

A

Accelerations: accelerations in foetal heart rate with movement or contractions is reassuring.

157
Q

What does the D stand for in Dr C Brvado in CTG foetal monitoring?

A

Decelerations: decelerations early with contractions = normal. decelerations with contractions = can be associated with cord compression. decelerations AFTER contractions= foetal hypoxia!

158
Q

What does the O stand for in Dr C Brvado in CTG foetal monitoring?

A

Overall assessment

159
Q

How do you grade perineal tears?

A

1st degree: perineal skin and vaginal epithelium
2nd degree: perineal skin and muscles
3rd degree: perineal skin and muscles AND anal sphincter
4th degree: skin, muscles, anal sphincter and rectum epithelium

160
Q

A woman has just given birth to a lovely baby girl. However 2 hours after she is still bleeding and has lost about 800ml of blood now. What is the likely diagnosis and how are you going to treat initially?

A

Primary PPH- loss of >500ml of blood in 24h
Treat:
ABCDE
IV fluids, oxygen, bloods- FBC, U&E, clotting, cross match
Blood transfusion if needed
Compression of uterus manually to stimulate contractions to stop bleeding
IV syntocinon/IV or IM ergometrine
Remove any retained products of conception

161
Q

What are the surgical options to treat PPH?

A

B Lynch compression sutures for c-section
Rusch balloon- inflate balloon to create pressure on uterus - for vaginal
Internal iliac/uterine artery ligation

162
Q

What are the causes of primary PPH?

A
4 T's 
Tone- uterine atony from prolonged labour, multiparty 
Trauma- perineal tears/episiotomy  
Tissue- retained products of conception 
Thrombin - clotting disorders eg. DIC
163
Q

A woman comes into clinic having given birth 2 weeks ago. She is describing heavy PV bleeding that started once she got home (2 days after giving birth). She also is describing some fevers and some abdominal pain. What is the likely diagnosis?

A

Secondary PPH likely due to endometritis from retained products of conception.

164
Q

What investigations would you do in a patient with secondary PPH?

A

Bedside: urinalysis, vaginal swabs
Bloods: FBC, U&E, clotting, group and save, blood cutures
Imaging: ULTRASOUND to look for retained products of conception

165
Q

How would you treat secondary PPH due to retained products of conception causing endometritis?

A

Antibiotics

Remove retained POC

166
Q

What happens with the uterus size and uterus discharge in the 6 weeks following birth (puerperium)?

A

Uterus size decreases
Discharge:
Lochia rubra- red discharge (blood) till day 3, then lochia serosa (yellow), then lochia alba (white)
Only US if lochia persists >6w

167
Q

What happens with the breasts/lactation in the 6 weeks following birth (puerperium)?

A

Breasts produce colostrum from last trimester to day 3-yellow fluid with fat, protein, minerals
At day 3- start producing milk.

168
Q

What hormones control production and ejection of breastmilk?

A

Production : prolactin from anterior pituitary

Ejection: oxytocin from posterior pituitary

169
Q

How do you reduce the risk of postnatal DVT/PE?

A

Encourage early mobilisation and hydration

Prophylactic LMWH

170
Q

What is the peak time for ‘baby blues’?

A

3-7 days following birth. doesnt last longer.