Obstetrics Flashcards
Booking bloods for pregnancy
Hb and platlets
HIV, syphilis, Hep B
Blood group and antibody status
Sickle cell and thalassaemia
When is the routine date scan usually done?
8+0 to 13+6 weeks
Blood tests for Down’s syndrome
A PAPPA-A
HCG
The quad test comprises of -
AFP
Inhibin A
Oestriol
Beta - Hcg
When is the quad test done ?
14-20 weeks
Diagnostic tests for Downs syndrome
Chorionic villous sampling
Amniocentesis
Private test for Downs syndrome
Cell free fetal DNA test
At what time is the anomaly scan done?
18+0 - 20+6
Risk factors for gestational diabetes
BMI >30 Some ethnic origins FH PCOS Previous baby >4.5kg Previous gestational diabetes
Potential sensitising events for Anti D
Spontaneous miscarriage Termination of a pregnancy Invasive procedures Traumatic events Placental abruption Fetomaternal haemorrhage Blood transfusions
When should prophylatic anti D be given?
28 weeks
Ages at risk if pregnant
<18
40+
What events in past pregnancies are significant ?
Premature labour Fetal growth restriction APH Gestational diabetes HTN Thrombocytopenia Types of delivery 3rd / 4th degree tear PPH Previous stillbirth, late miscarriage or neonatal death
Which family Hx is it important to elicit in this context?
Diabetes
HTN / pre eclampsia
Fetal growth restriction =
baby who does not reach it’s growth potential
risk factors for FGR -
Previous small baby pre-eclampsia / HTN reduced fetal movements maternal disease smoking
3 measurements used on US to estimate fetal weight -
abdo circumfrence
head circumfrence
femur length
How can a placental problem be identified?
Fetal vessel resistance
Reduced liquor volume
Management of FGR
Exclude underlying causes
Monitor
Timely delivery - fetal HR and blood flow
C-section?
Pregnancy induced hypertension =
HTN after 20 weeks
Pre-eclampsia -
HTN after 20 weeks with proteinuria
Risk factors for PET
First pregnancy Previous pre eclampsia >40 y/0 BMI 35 Multiple preg Pre-exisiting conditions
Maternal blood test when diagnosed with PET
u&e
LFTs
Urate
FBC
Fetal monitoring in a mum with PET
USS - fetal growth restriction
Markers of placental function
what infusion for eclampsia
magnesium sulfate
What happens in HELLP ?
Haemolysis, raised LFTs and low platelets (severe form of pre eclampsia)
What are obese women at risk of when pregnant?
Miscarriage Congenital malformations PET GDM Macrosomia VTE
What is the aim for BMI before falling pregnant?
<30
How is diabetes impacted by pregnancy
Increased insulin during preg
Worsening neuropathy and retinopathy
Increase in hypoglycaemic attacks
Maternal impacts of diabetes
Increase miscarriage risk Increase risk of PET Worsening renal disease Infections Higher induction rate LSCS rate higher Shoulder dystocia risk
Fetal impacts of diabetes
congenital malformations
unexplained still birth
Maternal hyperglycaemia leads to….
fetal hyperglycaemia which means there is increased production of insulin from the fetal pancreas. Therefore macrosomia can occur.
Before getting pregnant women with diabetes should….
lose weight quit smoking and alcohol take folic acid for 3m Switch to metformin / insulin HbA1c <48 Screened for retinopathy and nephropathy
How often should pregnant women be checking their BM?
Fasting
pre meal (omit if oral / diet controlled)
1hr post meal
bedtime
BM targets during pregnancy
Fasting <5.3
l hr post meal <7.8
maintaining above 4
USS app for women with diabetes in preg
Normal dating at 8-13 wks
Routine anomaly at 18-20
Serial growth scans every month from 28/40
What should be offered in terms of delivery for women with diabetes in preg
Elective delivery - IOL/ LSCS at 37-38+6
If complications can offer before 37 weeks
When should only LCSC be offered in women with diabetes in preg
EFW of >4.5kg
Which women are at risk of gestational diabetes?
BMI >30 Previous baby >4.5kg Previous GDM FH Ethnic origin
How is GDM diagnose?
28 weeks glucose tolerance test
fasting glucose >5.6
2 hr plasma glucose >7.8
Previous GDM what additional test should be done?
12-16/40 additional glucose tolerance test
When is FBC measured in preg?
Booking
28 weeks
Threshold for anaemia treatment in preg
<11g/dL @ booking
<10.5g/dL @ 28 weeks
What is the first line treatment for anaemia in preg?
Diet and ferrous sulfate.
Risk factors for VTE in pregnancy
Thrombophilia Age >35 BMI <30 Parity of >3 Smoker Immobility Gross varicose veins Multiple preg Medical co-morbidities Systemic infection
Up to when post delivery are women at risk of VTE?
6 weeks
Which group of women are particularly at risk of VTE post delivery and how are they treated?
C-section
given 7 days of LMWH
Initial imaging investigation for PE in pregnancy =
And what can be done next depending on the results?
CXR
normal / V/Q scan
Abnormal - CTPA
treatment of choice for VTE in pregnancy
LMWH
NOT WARFARIN
Management of HTN in preg
12weeks +
Aspirin 75mg OD
Treatment for eclampsa
MgSO4 - as decision to deliver is made
Monitor the urine output, reflexes, RR and SpO2
Fluid restriction - prevent overload
Advice on folic acid and pregnancy
400mg should be taken from roughly 3m before conception up to 12 weeks
Risks of not giving Anti-D in a preg.
Baby may become anaemic, fetal hydrops (accumulation of fluid) and risk of still birth
When is anti D given
28 weeks
or divided dose at 28 and 34 weeks
postnatally if sensitizing event
Obstetric causes of abdo pain in 2nd and 3rd trimester
Labour Placenta abruption Symphysis pubis dysfunction Ligamental pain Pre-eclampsia / HELLP
Gynae causes of abdo pain in 2nd and 3rd trimester
Ovarian torsion
Cyst rupture / haemorrhage
Uterine fibroid de-generation
GI causes of abdo pain 2nd and 3rd trimester
Constipation Pyelonephritis Gall stones / cholestasis Pancreatitis Peptic ulcer Cystitis Renal stones
from what number of weeks can a CTG be used?
26