Obstetrics 3 Flashcards

1
Q

To avoid fetal effects of antithyroid drugs…

A

dont use block replace regime

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2
Q

what should you do about a macroadenoma?

A

continue bromcriptine or cabergoline
monitor visual fields, headaches, diabetes insipidus

new dx? prolactin not reliable. Need imaging if suspect.

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3
Q

FEV1 and FVC in preg?

A

unchanged

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4
Q

DLCO in preg?

A

decreased

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5
Q

How long do you have to stop LMWH before spinal?

A

24-36 hours

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6
Q

Chorea gravidarum

A

Clinical feature in APL syndrome

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7
Q

Does MS affect preg outcomes?

A

NO

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8
Q

What effect will exclusively breast feeding for the first two months have on mum?

A

reduce relapse rate!

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9
Q

Recurrent headache for a month post partum think?

A

Cerebral vasoconstriction

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10
Q

Which AED are enzyme inducers?

A
Phenytoin
Phenobarbital
Carbamazepine
Oxcarbazepine
Topiramate
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11
Q

Classic picture post partum thyroiditis

A
Up to 12 months post pregnancy
Thyrotoxicosis
TPO positive
no uptake on scan
increase risk type 1 DM
If severe with T3>>T4 or ophthal- suggests graves

Treat with bblockers
No role for anti thyroid drugs
If hypo then T4 or if TSH over 10

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12
Q

What happens to T3,T4, TSH in normal preg?

A

TBG increase
Total T3,T4 increase
T3,T4 same free
TSH reduced early preg for a while as HCG acts on same receptor

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13
Q

UTI in preg- empirical ok?

A

Aug 500/125
cephalexin
nitrofurantoin

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14
Q

What does cat B mean

A

limited human exposures- ok
B1- animal studies ok
B2- limited animal data
B3- animal studies fetal damage of uncertain signif

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15
Q

Cat C means

A

suspected REVERSIBLE harm but not malformation

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16
Q

Cat D

A

suspect IRREVERSIBLE harm

17
Q

Cat X

A

do not use in preg or preconception

18
Q

What happens to factor V in preg? Factor II and IX?

A

V stays same
II and IX increase
all others decrease

Protein S decreases
Protein C no change
VWF increases

19
Q

FSH and LH in preg?

A

Decreased

20
Q

How long to continue LMWH post DVT?

A

minimum three months, and until 6 weeks post partum