Obstetrics 2 Flashcards
Why do you get DVTs in pregnancy?
increase pro coagulants like factor 5 and 7
reduce anticoag activity of protein C, S
Compression LEFT iliac vein by uterus
Can you give warfarin in breast feeding?
Yes
How to anticoagulate in preg?
LMWH then switch to UFH 4 weeks pre delivery
What does warfarin do to baby>
T1 fetal chondroplasia punctata
T2,3 fetal optic atrophy, mental retardation
What things go up in normal pregnancy?
cardiac output
plasma volume
GFR
What things go down in normal pregnancy?
plsma protein and albumin
plasma creatinine
SVR
plasma urea
Note sodium and osmolality stay the SAME
If hep B viral load high, give what in third trimester?
Tenofovir
Indications for delivery in diabetes in pregnancy?
Proliferative diabetic retinopathy
Worsening renal function
Usual indications for delivery
Risk of developing diabetes long term if have gestational?
40% in first 10 years
Obesity in pregnancy increase risk of
still birth congen malformation pre eclampsia UTI post date delivery
following bariatric surgery - wait one year
What happens to your thyroid hormone in normal preg?
Increase TBG so increase total T4, T3 but normal free portion.
What to use for T1 thyrotoxicosis?
PTU- crosses placenta less
By T2, T3 use carbimazole as crosses the placenta more but less associated with liver failure
Goal for TSH in pregnancy?
Keep in normal range
Kids of women with high TSH have lower neurocog scores
Headache with sixth nerve palsy in pregnancy?
Think idiopathic IC hypertension
What happens to MS risk in pregnancy?
Reduce flare in preg
Increase flare post preg