Obstetrics Flashcards
Alloimmunization
Maternal antibodies against fetal blood cells
Potentially sensitizing events in rh-d negative women
Chorionic villi sampling, amniocentesis, cordocentesis Threatened miscarriage Ectopic pregnancy Evacuation of molar pregnancy Termination of pregnancy Antepartum hemorrhage Abdominal trauma Intrauterine fetal death External cephalic version Delivery
Minimum volume of maternal-fetal hemorrhage that can lead to alloimmunization
0.1ml
Kleihauer-Betke test
Method for determining percentage of fetal blood in maternal circulation
At what gestational age should rhogam be given for threatened miscarriage
12 weeks
Rhogam for miscarriage?
50-120mcg before 12 weeks, especially after D&C
300 mcg after 12 weeks
Postpartum depression diagnostic criteria
5 out of 9 symptoms in the first four weeks after delivery
- Depressed mood
- Anhedonia
- Decreased energy
- Changes in sleep pattern
- Feelings of guilt or worthlessness
- Psychomotor slowing or agitation
- Suicidal ideation
- Decreased concentration
- Weight changes
Postpartum psychosis
Hallucinations, delusions, and profound thought disorganization that occurs in the first 2 weeks postpartum
Postpartum blues
Mild depressive symptoms, irritability, tearfulness, decreased concentration in the first 2-3 days postpartum and resolve by 10 days postpartum
Jarisch-Herxheimer reaction
Reaction to penicillin G with uterine contractions, fetal heart rate decelerations, and preterm labor, fever, myalgia
Usually resolves 24-48 hours
Ultrasound abnormalities associated with syphilis
Nonimmune hydrops Hepatomegaly Placentomegaly Polyhydramnios Ascites
Ultrasound indicated cerclage
Performed if cervical length during cervical length screening is <2.5cm
3-6 months postpartum
Autoimmune thyroid dysfunction
Major risk factor is positive thyroid antibodies in the first trimester and GDM
Thyrotoxicosis –> transient hypothyroidism –> euthyroid at 12 months PP
Antithyroid treatments aren’t helpful, use beta blocker
Postpartum thyroiditis
Kidney changes during pregnancy
Kidney size increases 1-1.5cm, decreases in 6 months PP
Mild to moderate hydronephrosis and hydroureter, particularly on the right side
The IUD insertion approach in a breastfeeding woman that is considered category 1 (no restrictions) according to US Medical Eligibility Criteria is:
copper IUD within 10 minutes of placental separation
Preferred treatment for depression in pregnancy
CBT, psychotherapy
Edinburgh Postnatal Depresson Scale positive score
> 10
Division of embryo before day 4
Dichorionic twins (and diamniotic)
Embryo division days 4-8
Monochorionic diamniotic twins
Embryo division day 9-13
Monochorionic monoamniotic twins
Embryo division after 13 days
Conjoined twins
Risk of listeria in pregnancy
13 times more likely than nonpregnant patients
Type of cheese that should be avoided in pregnancy
queso fresco
soft unpasteurized
Type of tuna that should be limited in pregnancy (to one serving per week)
Canned albacore tuna
Fresh tuna
(canned light tuna is very low in methylmercury)
Fish that should be avoided in pregnancy
Tilefish from Gulf of Mexico shark swordfish marlin orange roughy bigeye tuna king mackerel
Huntington procedure
For correcting uterine inversion
Serial clamping and upward traction on the round ligaments to restore uterine position
Haultain procedure
For correcting uterine inversion
Cervical ring is incised posteriorly to aid in repositioning of the uterus
Treatment of mastitis abscess
Drainage and culture (keep dicloxicillin going)
17 y/o with painless fluctuant, fluid filled 6cm mass on left lateral vagina, 4cm cephalad to hymenal ring
Mesonephric duct remnant
Major modifiable risk factors for obstetric anal sphincter injuries
Forceps-assisted delivery
Vacuum extraction
Prolonged second stage
Midline episiotomy
Most likely fetal karyotype with Tetralogy of Fallot
46 XY
Tetralogy of Fallot
VSD
Overriding aorta
Pulmonic valve stenosis
Right ventricular hypertrophy
Type of prenatal diagnostic test to perform if it’s because you find congenital heart disease
Genomic microarray
Congenital heart defect associated with Down syndrome
ASD
What is the infectious disease for which prepregnancy interventions are most likely to improve perinatal outcome?
HIV
Low PAPP-A correlates with
Low birth weight
Advantages of delivering at higher level NICU
Lower mortality Decreased severe intracranial hemorrhage Decreased respiratory distress syndrome Decreased patent ductus arteriosis Decreased nosocomial infections
Contraindicated vaccines in pregnancy
Live influenza
MMR
Varicella
Zoster
Most common nutrient abnormalities after Roux-en-Y gastric bypass
Protein Iron Vitamins B12 and D Folic acid Calcium
Highest risk for infection after needle stick
Hepatitis C