Obstetric Viruses Flashcards
(19 cards)
What is “possible Zika virus exposure”?
Travel to or residence in an area of active Zika transmission or unprotected intercourse with a partner who traveled to or lived in that area
How is zika virus transmitted?
Sexual contact, blood, and transplacental
How long should a man wait to attempt pregnancy after Zika exposure?
3 months
How long should a woman wait to attempt pregnancy after Zika exposure?
8 weeks
What is Zika virus?
Flavivirus transmitted by Aedes mosquitoes
What is “ongoing Zika virus exposure”?
Currently living in or frequent travel to areas with active Zika transmission
Zika virus incubation period
3-14 days
Signs and symptoms of Zika infection
Fever, rash, arthralgia, conjunctivitis
What birth defects of associated with Zika virus?
Microcephaly, thin cerebral cortex, subcortical calcifications, retinal abnormalities, congenital contractures, early hypotonia
What adverse pregnancy outcomes are associated with Zika virus?
Miscarriage, preterm birth, IUGR, stillbirth
Risk of congenital Zika virus syndrome
5-10%
Who definitely needs testing for Zika virus?
Symptomatic pregnant women with possible Zika exposure, women who are pregnant with a fetus showing consistent anomalies
Who can be offered testing for Zika virus?
Asymptomatic pregnant women with ongoing possible exposure, symptomatic nonpregnant women with possible exposure
How should fetuses be monitored in women with suspected Zika infection?
Special ultrasounds for detection of anomalies and growth scans
How should symptomatic pregnant women be tested for Zika virus?
Dengue and zika NAAT and IgM serum + Zika NAAT urine within 12 weeks of symptom onset
How should asymptomatic pregnant women with ongoing exposure be tested for Zika virus?
Zika virus NAAT 3 times in pregnancy
How should pregnant women with fetal findings consistent with congenital Zika be tested for Zika virus?
Zika virus NAAT and IgM on serum, NAAT on urine
How is parvovirus B19 infection diagnosed?
IgM antibodies or seroconversion of IgG titer
How are fetuses screened with a maternal parvovirus B19 infection?
MCA dopplers and monitoring for hydrops for 10-12 weeks after exposure/acute infection
