Obstetric Viruses Flashcards

1
Q

What is “possible Zika virus exposure”?

A

Travel to or residence in an area of active Zika transmission or unprotected intercourse with a partner who traveled to or lived in that area

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2
Q

How is zika virus transmitted?

A

Sexual contact, blood, and transplacental

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3
Q

How long should a man wait to attempt pregnancy after Zika exposure?

A

3 months

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4
Q

How long should a woman wait to attempt pregnancy after Zika exposure?

A

8 weeks

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5
Q

What is Zika virus?

A

Flavivirus transmitted by Aedes mosquitoes

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6
Q

What is “ongoing Zika virus exposure”?

A

Currently living in or frequent travel to areas with active Zika transmission

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7
Q

Zika virus incubation period

A

3-14 days

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8
Q

Signs and symptoms of Zika infection

A

Fever, rash, arthralgia, conjunctivitis

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9
Q

What birth defects of associated with Zika virus?

A

Microcephaly, thin cerebral cortex, subcortical calcifications, retinal abnormalities, congenital contractures, early hypotonia

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10
Q

What adverse pregnancy outcomes are associated with Zika virus?

A

Miscarriage, preterm birth, IUGR, stillbirth

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11
Q

Risk of congenital Zika virus syndrome

A

5-10%

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12
Q

Who definitely needs testing for Zika virus?

A

Symptomatic pregnant women with possible Zika exposure, women who are pregnant with a fetus showing consistent anomalies

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13
Q

Who can be offered testing for Zika virus?

A

Asymptomatic pregnant women with ongoing possible exposure, symptomatic nonpregnant women with possible exposure

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14
Q

How should fetuses be monitored in women with suspected Zika infection?

A

Special ultrasounds for detection of anomalies and growth scans

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15
Q

How should symptomatic pregnant women be tested for Zika virus?

A

Dengue and zika NAAT and IgM serum + Zika NAAT urine within 12 weeks of symptom onset

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16
Q

How should asymptomatic pregnant women with ongoing exposure be tested for Zika virus?

A

Zika virus NAAT 3 times in pregnancy

17
Q

How should pregnant women with fetal findings consistent with congenital Zika be tested for Zika virus?

A

Zika virus NAAT and IgM on serum, NAAT on urine

18
Q

How is parvovirus B19 infection diagnosed?

A

IgM antibodies or seroconversion of IgG titer

19
Q

How are fetuses screened with a maternal parvovirus B19 infection?

A

MCA dopplers and monitoring for hydrops for 10-12 weeks after exposure/acute infection