Obstetric + Perinatal infections Flashcards

1
Q

What is different in pregnancy in terms of infection for the mother

A

Physiological and imunological changes may increase susceptabilty and alter clinical manifestations
some drugs are contraindicated

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2
Q

What infections are different in pregnant and non pregnant women

A

UTI ( may be pyelonephritis)
Varicella
Rash ( maybe rubella or parovirus)

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3
Q

Give five examples of bacterial congenital infections

A
Cytomegalovirus
Toxoplasmosis
Rubella
Varicella
Syphilis
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4
Q

What does CMV infection ause

A

Congenital infection and fetal damage

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5
Q

Is timing important with CMV

A

no

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6
Q

How is congenital rubella trasmitted

A

Placentally

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7
Q

Is the outcome timing dependant for rubella

A

Yes

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8
Q

What are the different effects in timing with Rubella

A

1st tri- mulitiple developmental defects ( CNS heart eye)
12-18weeks- deafness
after 18 weeks- no risk

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9
Q

How can congential rubella be prevented

A

MMR vaccine
antenatal screening
post partum vaccination
investigation of all maternal rashes

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10
Q

What is toxoplasmosis, and what does it cause

A

Protozaon, brain damage and choroido-retinitis

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11
Q

What does congential Varicella cause

A

Skin loss, scarring, usually unilateral and segmented
impaired skin bud development
non-specfic- microcephaly - IUGR - cataracts

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12
Q

What is the overall risk of HIV mother to baby transmission and how can it be reduced

A

20%
maternal antiretroviral therapy
C-section
no breastfeeding

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13
Q

How is mother to baby HBV AND HCV transmission prevented

A

Vaccine for HBV

no vaccine for HCV

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14
Q

What is neonatal septiceamia/ meningitis caused by

A

Group B streptococcus
E.coli
and less commonly Listeria Monocytogenes

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15
Q

What can group B strep cause in neonates

A

Pneumonia septiceamia and mengingitis

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16
Q

Where is group B Strep normally found

A

Normal gut flora

17
Q

What is the significance of maternal chicken-pox

A

Varicella pneumonia
in first 20 weeks - risk of fetal damage
late preg- neonatal chicken pox

18
Q

What are the symptoms of neonatal herpes

A

50% internally disseminating infection without external lesions
50% external lesions and IDI

19
Q

What is the prognosis like for neonatal herpes

A

Awful

20
Q

What causes Opthalmia neonatorum

A

Neisseria gonorrhoae

Chlamydia Trachomatis

21
Q

What is opthalmia neonatorum

A

Acute purulent conjunctivitis