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Leeds MBCHB Year 4 GOSH > Obstetric Drugs > Flashcards

Obstetric Drugs Flashcards

1
Q

Oxytocin indications

A

Induce labour
Progress labour
Improve frequency and strength of contraction
Prevent and treat postpartum haemorrhage

Placental delivery

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2
Q

Oxytocin receptor antagonist

A

Atosiban

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3
Q

Atosiban indication

A

Second line tocolysis in premature labour (nifedipine is 1st)

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4
Q

Ergometrine MOA

A

Smooth muscle contraction in uterus and blood vessels

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5
Q

Ergometrine use

A

PPH

Assist with placental delivery (only can be used after baby delivered)

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6
Q

Prostaglandins use

A

Ripening cervix before delivery

Contract uterine muscles

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7
Q

Misoprostol

A

Prostaglandin analogue

Medical abortions (alongside mifepristone)
IOL
Intrauterine fetal death (to deliver baby)
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8
Q

Mifepristone - drug type and indications

A

Anti-progesterone

Medical abortions - USE FIRST (alongside misiprostol) - ripens cervix
IOL
Intrauterine fetal death (to deliver baby)

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9
Q

Nifedipine

A

CCB

Reduce blood pressure in HTN and Pre-E
Tocolysis in premature labour

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10
Q

Terbutaline use

A

Tocolysis in uterine hyper stimulation

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11
Q

Carboprost

A

Prostaglandin analogue

Stimulates uterine contraction in PPH - GIVE IM

CANNOT BE USED IN ASTHMA

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12
Q

IV magnesium sulphate use

A

Seizures associated with pre-eclampsia

Neuroprotection up to 34 weeks

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13
Q

What is given first? Mifepristone or misoprostol

A

Mifepristone (ripens cervix)

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14
Q

Why should NSAIDs be avoided in pregnancy

A

Can increase BP

Closure of FDA

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15
Q

Ergometrine contraindication

A

HTN/ eclampsia

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16
Q

Time between maternal steroids

A

24 hours but can do 12

17
Q

MgSO4 is given to preterm babies at what week

A

Less than 34

18
Q

Steroids are given to mum if baby born under

A

Less than 36

19
Q

Sign of MgSO4 toxicity

A

Reduced RR, reduced BP, absent tendon reflex’s

20
Q

Terbutaline drug class

A

B2 agonist

21
Q

When is the only time terbutaline is used for tocolysis

A

uterine hyperstimulation from induction

22
Q

Most common drug for tocolysis

A

Nifedipine

Leeds MBCHB Year 4 GOSH (10 decks)

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