Obstetric Complications Flashcards
Definition of preterm labour?
Between 24 and 37 weeks’ gestation - 8% of deliveries
Risk factors for preterm labour?
- Previous history
- Low SE status
- Extremes of maternal age
- Short inter-pregnancy interval
- Maternal disease (renal/DM)
- Pregnancy complications (pre-eclampsia/IUGR)
- Male foetal gender
- High Hb
- STIs/vaginal infection (BV)
- Previous cervical surgery (LETTZ)
- Multiple pregnancy
- Uterine abnormalities and fibroids
- Urinary infection
- Polyhydramnios
- Congenital foetal abnormalities
- Antepartum haemorrhage
Mechanisms of preterm labour? (defenders)
Multiple pregnancy and polyhydramnios
Foetal survival response (pre-eclampsia, IUGR, infection, abruption)
Mechanisms of preterm labour? (castle/wall)
Uterine abnormalities (fibroids, congenital)
Cervical incompetence
Mechanisms of preterm labour? (enemy)
Chorioamnionitis, BV, GBS, trichomonas, chlamydia
UTI/dental infections
Neonatal complications of preterm labour?
Prematurity –> 80% neonatal ICU occupancy, 20% perinatal mortality, 50% cerebral palsy.
Long-term
Chronic lung disease, blindness, minor disability.
Maternal complications of preterm labour?
Infection –> endometritis
How to predict preterm labour?
TV USS of cervical length at 23 weeks (<15mm)
Prevention of preterm labour in high risk individuals?
Cervix - suture in cervical incompetence + regular scanning
Infection - screening and treatment (STIs, UTI, BV)
Foetal reduction - higher order pregnancies
Polyhydramnios - needle aspiration, NSAIDs (reduce foetal urine)
Progesterone pessaries - suppositories from early pregnancy
Clinical features of preterm labour?
History = painful contractions, cervical incompetence (suprapubic ache), antepartum haemorrhage and fluid loss common
Exam = fever, check lie and presentation, digital vaginal exam unless ruptured membranes - effaced or dilating cervix confirms diagnosis
Investigations in preterm labour?
Foetus - CTG and USS
Likelihood of delivery - foetal fibrnoectin assay, TV USS of cervical length
Infection - high vaginal swabs, maternal CRP - WCC unhelpful
Management of preterm labour?
Pulmonary maturity - steroids and tocolysis
Infection - IV abx and immediate delivery if chorioamnionitis
Delivery - vaginal usually, c-section for usual indications. Can use forceps but ventouse contraindicated. Abx due to risk of GBS.
What do you need to be careful with with steroids?
Glucose control in diabetics
Examples of tocolytics? What do they do? How long should you use them for?
o Nifedipine/atsodiban (oxytocin receptor antagonist).
o Delay preterm labour – should not be used for more than 24 hours.
o Allows steroids time to work, or time for in utero transfer to facilitiy with neonatal ICU facilities.
Definition of antepartum haemorrhage?
Bleeding from genital tract after 24 weeks’ gestation
Causes of APH?
Undetermined origin
Placental abruption
Placenta praevia
Rarer = incidental genital tract pathology, uterine rupture, vasa praevia
What is placenta praevia?
Placenta is implanted in lower segment of the uterus
Will a low-lying placenta necessarily be praevia at term?
Only 1 in 10 apparently low-lying placentas will be praevia at term (myometrium where placenta inserts moves away from cervical os)