Obstetric Anesthesia & Complications - Quiz 1 Flashcards
What are the Neuro Changes of Pregnancy?
Decreased MAC, Epidural Space, and CSF
Engorged Epidural Veins
Increased LA Sensitivity
What are the Respiratory Changes of Pregnancy?
↑TV (40%)
↑RR (15%)
↑Minute Ventilation (50%)
↓PaCO2
Which of the following is decreased during Pregnancy?
A. Vital Capacity
B. Total Lung Capacity
C. Functional Residual Capacity
D. Dead Space
E. Airway Resistance
↓FRC (20%)
↓Dead Space
↓Airway Resistance
What Respiratory changes helps delivery of oxygen to fetus?
Increase of P50 Hemoglobin from 27 to 30 mmHg
What happens to the Respiratory Mucosa during Pregnancy?
Congestion d/t Vasodilation
Mucosal Engorgement = ↑Mallampati
What makes the mother prone to hypoxia during pregnancy?
↓FRC & ↑O2 Consumption
Preoxygenate & RSI w/ Cricoid Pressure
Why should Hyperventilation be avoided in Pregnancy during Anesthesia?
Low PaCO2 causes uterine vasoconstriction decreasing placental blood flow & left HgbO2 shift
What Intubation equipment should be available for Pregnant Patients?
Smaller ETT
Shorter Handle
Avoid Nasal Intubation
How is Oxygen Delivery optimized during Pregnancy?
↑Cardiac Output
Right HgbO2 Shift
↓PVR d/t Increased Progesterone
How is Plasma Volume affected by Pregnancy?
Increased Plasma Volume d/t Increased Renin
What are the different phases of changes in Cardiac Output during Labor?
- Latent Phase: ↑15%
- Active Phase: ↑30%
- Second Stage: ↑45%
- Postpartum: ↑80%
What are the CV changes during Pregnancy?
Blunted Adrenergic Response
Cardiac Hypertrophy
Heart Murmurs
↓Plasma Colloid Osmotic Pressure
What is Supine Hypotension Syndrome?
Hypotension, Pallor, N/V, and Diaphoresis when Preggos lie flat
What is the best position for Supine Hypotension Syndrome?
Left Lateral Uterine Tilt
How does the blood change in a pregnant patient?
Depressed Cell-Mediated Immunity
Hypercoagulation
PT/PTT decreases by 20%
Which Coagulation Factors are Increased during Pregnancy?
1, 7, 8, 9, 10, 12
Which Coagulation Factors are Decreased during Pregnancy?
11 & 13
Which Coagulation Factors are uneffected by Pregnancy?
2 & 5
What are the Renal Changes during Pregnancy?
↑Blood Flow & Filtration
↓BUN & Creat
Mild Glycosuria & Proteinuria
How does Pregnacy affect the Gastroesophageal Sphincter?
Reduced Competence & Tone
What are the GI Changes during Pregnancy might increase Aspiration Risk?
Increased Acid Secretion & Gastric Fluid
How is the Gallbladder affected by Pregnancy?
Sluggish & Gallstones d/t decreased CCK
How is the Liver affected by Pregnancy?
Decreased Pseudocholinesterase
(No effect on Sux Duration)
How does Pregnancy affect Blood Glucose?
Insulin Resistance = ↑Blood Glucose transfer to Fetus
What are the methods of transfer accross the Placenta?
Diffusion
Bulk Flow
Active Transport
Pinocytosis
Breaks
How long can the Fetus live without Oxygen?
10 minutes
What is the transfer of Oxygen to the Fetus dependent on?
Maternal Uterine Blood Flow vs. Fetal Umbilical Blood Flow
How much Oxygen is stored and consumed by the Fetus?
Stored O2: 42 mL
Consumed O2: 21 mL/min
How does the Fetus compensate for the Placental PaO2 of 40 mmHg?
Mom: Right HgbO2 Shift
Fetus: Left HgbO2 Shift & More Hgb
How is CO2 transfered across the Placenta?
Simple Diffusion
Fetal Hgb has lower CO2 affinity than Mom
Normal Uterine blood flow is 50 mL/min. How much is that increased during Pregnancy?
600-700 mL/min (10% of Cardiac Output)
80% of that goes to Placenta; the rest to Myometrium
What factors affect Uterine Blood Flow (UBF)?
BP
Uterine Vasoconstriction
Uterine Contractions
What anesthetic agents and drugs can decrease Uterine Blood flow?
Thiopental
Propofol
Gases > 1 MAC
How does Ketamine, Opioids, and N2O affect Uterine Blood FLow?
Little to No Effect