Obs notes Flashcards
At what week does the heart start to beat ?
- Week 6
What are the 3 layers of the fetal pole ?
- Ectoderm
- Mesoderm
- Endoderm
What parts of the body come from the endoderm
- GI tract
- Lungs
- Liver
- Pancreas
- Thyroid
What parts of the body come from the mesoderm
- Heart
- Muscle
- Bone
- Connective tissue
- Blood
- Kidneys
What part of the body comes from the ectoderm
- Skin
- Hair
- Nails
- Teeth
- CNS
What produces hCG
- Syncytiotrophoblasts
- This maintains the corpus luteum in the ovary allowing it to continue to continue to produce progesterone and oestrogen
Ovulation occurs following a surge of what hormone ?
- LH surge from the pituitary causing the smooth muscle of the theca externa to squeeze the follicle to burst
- Follicular cells also release digestive enzymes that puncture a hole in the wall of the ovary allowing the ovum to pass through
What is the function of the placenta ?
- The only source of oxygen for the fetus
- Fetal haemoglobin has a higher affinity for oxygen than adult and this oxygen transfers from one to the other across the placental membrane
What is the role of hCG
- Helps maintain the corpus luteum until the placenta can take over the production of oestrogen and progesterone
- hCG can cause symptoms of nausea and vomiting
- Levels increase in early pregnancy and plateau around 10 weeks
What is the role of oestrogen in pregnancy ?
- The placenta produces oestrogen which helps soften the tissues and make them more flexible
- Allows the muscles and ligaments of the uterus and pelvis to expand and the cervix to become soft and ready for birth
- (Also enlarges the breasts and prepares them for breastfeeding)
What is the role of progesterone in pregnancy ?
- The placenta takes over production of progesterone by 5 weeks
- The role of progesterone is to maintain pregnancy
- It relaxes the uterine muscles (preventing contraction and labour) and maintains the endometrium
What are side effects of progesterone in pregnancy ?
- Causes relaxing of other muscles too
- Lower oesophageal sphincter (causing heartburn), the bowel (causing constipation) and the blood vessels (hypertension, headaches and flushing)
- Also raises body temp between 0.5-1
What is gestational age ?
- Refers to the duration of pregnancy starting from the date of the last menstrual period
Gravida
- Number of pregnancies
Para
- Number of times a patient has given birth after 24 weeks gestation, regardless of whether the fetus is alive or still born
G&P of A pregnant patient with three previous deliveries at term
- G4 P3
G&P of A non-pregnant person with a previous birth of healthy twins
- G1 P1
G&P of A non-pregnant person with a previous miscarriage
- G1 P0+1
G&P of A non-pregnant person with a previous stillbirth (after 24 weeks gestation)
- G1 P1
Conditions identified with parental screening ?
- Trisomy 21 Down’s
- Trisomy 18 Edward’s
- Trisomy 13 Patua’s syndrome
- 45XO Turner’s syndrome
- 47XXY Klinefelter’s syndrome
What is the combined screening test ?
- USS (Nuchal)
- Blood test – PAPP-A and b-hCG
Quadruple tests – 15 weeks
- AFP reduced
- Oestriol reduced
- hCG increased
- Inhibin A increased