Obs Infections and Illness Flashcards
5 important infections
CMV Herpes zoster Rubella Syphilus Toxoplasmosis Group B Strep
CMV in pregnancy
Impairment in baby hearing, and vision, IUGR, cognitive and motor deficits.
No treatment, offer termination.
Herpes zoster in pregnancy
Transmission is rare. Severe neonatal infections can cause neuro damage and death.
Prevent with immunoglobulins.
If baby is ill use acyclovir to treat.
Rubella in pregnancy
Infection before 12 weeks gestation = visual (cataract) and hearing impairment, renal artery stenosis, cardic problems, thrombocytopenia and IUGR.
No treatment, offer termination before 16wks. Severity of infection decreases with advancing gestation.
Syphilis in pregnancy
Offer screening test at antenatal appoitments.
Treat with Benzylpenicillin ASAP.
Toxoplasmosis
Contaminated cat faeces and red meat.
Infection causes visual and cognitive impairments.
Rx for acute infection = Spiramycin ASAP
Rx for suspected infection = pyrimethamine, sulfadiazine, and folinic acid
Group B streptococcus
Risk factors = preterm, prolonged rupture of membranes, maternal fever, previous neonate with GBS.
Vertical transmission from vaginal colonies.
Rx = IV penicillin
Organisms and test for Syhphilis in pregnancy
Treponema pallidum antibody screening test at 1st antenatal appointment - treponemes can cross placenta after 15weeks gestation and infect fetus.
Another name for Rhesus disease
Haemolytic disease of the fetus and newborn.
Occurrence of Rhesus disease
Maternal blood = Rhesus negative with previous sensitisation to RhD positive blood e.g. previous pregnancy, chronic villus sampling.
Fetal blood = Rhesus positive.
Clinical features of Rhesus disease and management
Fetus = anaemia, bradycardia. Neonate = Jaundice, haemolytic anaemia, hypotonia, lethargic. Treatment = Phototherapy, blood transfusion, IV immunoglobulins within 72hrs.
Obstetric cholestasis
Itch, NO RASH, abnormal LFT - resolves after delivery and LFT should be done 10days post to confirm
