obs/gynae Flashcards
what happens to total plasma volume in pregnancy
increases by around 30-50%
what happens to kidney function in pregnancy
increases
what happens to BP in pregnancy
biphasic
decreases in early/mid pregnancy
increases in late pregnancy
what is aortocaval compression syndrome
compression of the abdominal aorta and inferior vena cava when pregnant woman lies supine
what speculum is used to examine prolapse
sims
lifestyle modifications for prolapse
weight loss
smoking cessation
reduce caffeine intake
avoid straining/constipation
what type of cells make up detrusor muscle
transitional epithelium
where do the sympathetic nerve fibres come off the spinal cord to relax the bladder
T11-L2
where do the parasympathetic nerve fibres come off the spinal cord to contract the bladder
S2-S4
what receptors are on the detrusor muscle
muscarinic M2 and M3
name some anticholinergics
oxybutynin
tolterodine
(propiverine, trospium, solifenacin)
side effects of oxybutynin
dry mouth
blurred vision
drowsiness
constipation
what class of drugs are given to manage incontinence
anticholinergics, antimuscarinics and beta-2 adrenergic agonists
name a beta-3 adrengeric agonist
mirabegnon
when is a person said to be in menopause
12 months of amenorrhoea
onset of symptoms if hysterectomy
what characterises perimenopause
irregular periods and symptoms
what are the central effects of decreased oestrogen levels in perimenopause
hot flushes/sweats
joint muscle/pain
low mood + sexual difficulties
what are the local effects of decreased oestrogen in perimenopause
vaginal dryness due to vaginal atrophy
non-hormonal medication to treat menopause
clonidine
indications for transdermal oestrogen
gastric upset e.g. crohns
need for steady absorption e.g. migraines/epilepsy
increased risk of VTE
older women
medical conditions e.g. htn
what is premature ovarian insufficiency
menopause <40
how do you diagnose premature ovarian insufficiency
FSH > 30 (2 samples more than 4 weeks apart)
4 months of amenorrhoea
medication often used for HRT in breast cancer patients
venlafaxine
problems with benzodiazepines in pregnancy
associated with cleft palate, neonatal withdrawal syndrome and floppy baby syndrome
avoid in 3rd trimester