Obs 2017 Flashcards
When / what is done in the booking visit?
When is the combine test?
When is the anomaly scan?
Before 10 weeks - screen for complications
-urine culture, FBC, antibody screen, syphilis, rubella. HIV, hep b
11-13wks
18-21 weeks
What does the combine test involve? Levels in downs ? Other disease it looks for? What is offered if there is a 1 in 150 risk of downs or more?
Blood sample
- pregnancy associated plasma protein-A (PAPP-A)
- Free B-hCG
Ultra sound scan
-Nuchal translucency
Downs - PAPPA=low, NT/BHCG=raised
Edwards
Another US and CVS or amniocentesis
What happens in an anomaly scan (20 week scan)? What 3 things are measured ?
US Shape of brain and head Check cleft lip Spine Abdo wall covers organs Heart Kidneys Hands and feet Placenta
Will measure - head circumference, abdominal circumference, femur length
What is amniocentesis?
When is it Safe?
What can it diagnose?
What is the risk?
Ultrasound guided removal of a sample of amniotic fluid
Safest from 15 week gestation
Can diagnose chromosomal abnormalities, infections (e.g. CMV), inherited disorders (e.g. sickle cell anaemia, cystic fibrosis)
Risk of miscarriage (1%)
What is cvs? When can it be done? What advantage over amniocentesis?
Biopsy of trophoblast
Done after 11 weeks
Earlier than amniocentesis so abortion could still be performed if abnormality identified
Treatment of pulmonary oedema as a complication of pre eclampsia
Furosemide, oxygen
Maternal complications of pre eclampsia?
Eclampsia: grand mal seizures, Tx magnesium sulphate
Cerebrovascular haemmorhage
‘HELLP’ syndrome: Haemolysis, Elevated Liver enzymes, Low Platelets
Other: DIC, liver failure, liver rupture
Renal Failure
Pulmonary oedema, Tx furosemide, oxygen
Fetal complications of pre eclampsia
IUGR
Placental abruption
Preterm birth
3 aspects of screening / prevention of pre eclampsia
Regular BP and urinalysis checks, uterine artery doppler, 75mg aspirin starting before sixteen weeks in high risk women.
Mx of pre eclampsia
When do you use antihypertensives?
Steroids?
Delivery time?
Antihypertensives if BP >150/100,
Steroids if moderate/severe at <34wks
Delivery: Mild by 37 wks, moderate/severe 34-36 wks, maternal complications deliver whatever the gestation
Which type of maternal antibody crosses the placenta in RBC isoimmunization?
IgG
What scalp pH would indicate significant fetal hypoxia
<7.2
4 methods of induction
Prostaglandins:
Prostaglandin E2 gel
Inserted into the vagina posterior to the cervix
Starts labour or alters the ripeness of the cervix allowing amniotomy
Amniotomy:
Artificial rupture of the membranes using an amnihook
Natural Induction:
Cervical sweeping
Use of finger to strip between membranes and uterus
Oxytocin:
Used alone if there is spontaneous rupture of membranes or following amniotomy after around 2 hours if labour hasn’t started
Ix and management of placenta previa
Investigations
FBC, U&E, Clotting, Group and save
USS
CTG
Management Admit (until delivery if previa) Resuscitation Steroids Anti-D (if resus negative) C-section
Absolute CI to VBAC ?
Placenta/vasa previa
Cephalopelvic disproportion
4 ways f preventing vertical transmission of HIV?
Maternal ART
Elective C/S
Avoid breast feeding
Neonatal ART
What is in the quadruple test for downs?
B-hCG, AFP, Inhibin-A and free estriol 3 (after 14 weeks)
Vomiting in pregnancy in around 50% but what is hyperemesis gravidarum ? Mx?
Severe vomiting with dehydration and electrolyte abnormalities
IV rehydration, anti-emetics, thiamine and psychological support
Cause? Diagnosis and mx of gestational diabetes?
Increased insulin resistance
Glucose tolerance test at 24-28 weeks
Metformin 1st line
Insulin 2nd line