Objective 4: Identify microbial pathogens that exhibit significant antigenic variation

Question 1

4 modes of immune evasion by microbes

Answer 1

1. being inaccessible to the immune response (ex: capsule)
2. resisting complement-mediated lysis and phagocytosis
3. varying or shedding antigens (bacteria and viruses do this to eade our immune systems and can get flu and strep numerous times)
4. causing specific and non-specific immunosuppresion

Question 2

Top 3 Finalist

Answer 2

1. Rhinoviruses (Colds)
2. Influenza virus (Influenza)
3. Neisseria gonorrhoeae (Gonorrhea)

Question 3

Bottom 5 Losers

Answer 3

4. Borrelia hermsii (relapsing fever)
5. Borrelia burgdorferi (Lyme dz)
6. Trypanosom brucei (African sleeping sickness)
7. Giardia lamblia (Giardiasis)
8. Plasmodium falciparum (SEVERE malaria)