OBGyn Flashcards
Amenorrhea (Primary)
No menses by 13 yo w/ no 2/2 sex characteristics or
No menses by 15 yo with normal 2/2 sex characteristics
Eti:
- Pregnancy
- Imperforate hymen
- Gonadal dysgenesis (Turner’s syndrome)
- HPO axis abnormalities (anorexia, bulimia, wt loss, excessive exercise)
Dx:
- Quantitative B-HCG
- FSH
- prolactin
- TSH, T3, Free T4
- estrogen & progesterone
Risk of Osteoporosis in Primary Ovarian failure
Amenorrhea (Secondary)
Absence of Menses for 3 mos for those with regular menstruation
or for 6 mos for women with irregular cycles
MCC - Pregnancy, Endometrial atrophy, Premature Ovarian Failure, pitutiary dysfx
Dx:
- quant B-HCG, TSH
- Prolactin if > 200 then get CT of Sella Turcica
- Progresterone challenge
- FSH
Tx:
underlying cause, use OCP, cyclic progesterone 10 mg for 10 days
Dysfunctional Uterine Bleeding
Eti, sxs
Excessive uterine bleeding w/ no organic cause
- Menorrhagia - prolonged/heavy bleeding (>7d or >80mL[5.4 tbs}); regular intervals
- Metrorrhagia - variable amt of bleedings at irregular, freq intvls
- Menometrorrhagia - more blood loss during menses, freq and irregular bleeding btwn menses (heavy, freq, irregular)
- Polymenorrhea - more freq <21 days
- Oligomenorrhea - > 35 days
Eti:
PALM - Structural causes
- Polyp - submucosal fibroid or polyp
- Adenomyosis
- Leiomyoma
- Malignancy
COEIN - Nonstructural causes
- Coagulopathy
- Ovulatory dysfx
- Endometrial
- Iatrogenic
- Not classified
DUB
Dx, tx
Diagnosis of exclusion
- r/o organic causes, reproductive, iatrogenic
- R/o preg
- med reconcilation
PE: thyromegaly , pelvic structural abns (polyps/fibroids)
Labs - FSH, LH, Prolactin, estradiol, testosterone, TSH/T3/T4, DHEAS, coags
Eval of uterus - EMB, hysterectomy, pelvic US
Uterine D&C (gold std) - diagnostic or therapeutic
Ectopic Pregnancy
eti, sxs
eti:
implantation of fertilized ovum outside uterine cavity
MC implantation in Fallopian tube (Ampulla)
RF:
previous abd sx, adhesions, PID, OCPs/IUD, tubal ligation
Sxs:
- Triad
- unilateral pelvic/abd pain
- vaginal bleeding
- amenorrhea/pregnancy
- cervical motion tenderness
- adnexal pain
Ruptured Ectopic - EMERGENCY
- severe abd pain
- dizziness
- N/V
- Shock signs - syncope, tachycardia, hypotension
Ectopic Pregnancy
dx
Serial B-HcG - should double q24-48 hrs
- initial <1500, repeat 2-3 day
Transvaginal US
- if HcG > 2000 with no gestational sac = Ectopic
Ectopic Pregnancy
tx
Unruptured/Stable
Methotrexate if
- Hemodynamically stable
- HcG < 5000
- No fetal tones
- Ectopic <3.5cm
- no renal, hepatic, pulm
Successful if b-HcG >=15% 2 blood draws
Lap Salpingostomy if ruptured
Endometriosis
eti, sxs
Presence of endometrial tissues outside uterine cavity - MC in ovaries, fallopian
RFs:
- nulliparity
- fam hx
- early menarche
Sxs
- 3 D’s
- Dyspareunia
- Dyschezia
- Dysmenorrhea
- Infertility
- Cyclic pelvic pain peak 1-2 d before menses onset
Endiometriosis
Dx, Tx
Lap with bx - definitive dx
Tx
- OCPs
- Leuprolide - gnRH analog
- Danazol /testosterone - suppresses mid surge LH –> only for 6 mos d/t bone loss
- Conservative Lap w/ ablation - if desire to conceive
- Total Abd Hysterectomy w/ Salpingo-oophorectomy - if no desire to conceive
Pelvic Inflammatory Disease
eti, sxs
Ascending infection of Upper genital Tract
MC N gonorrhea, Chlamydia
RF:
- multiple sex partners
- abd pain
- unprotected sex
- prev PID
- age 15-19
- iatrogenic causes IUD placement
Sxs
- lower abd tenderness
- fever
- purulent cervical discharge
- chandlier sign - cervical motion tenderness
Pelvic Inflammatory Disease
dx, tx
Dx:
- Abdominal tenderness
- Cervical motion tenderness
- adnexal tenderness plus one of the following:
- Fever >38C
- WBC >10,000
- Pelvic abscess via manual exam or US
- ESR/CRP
Tx
Outpatient - Doxycycline 100mg BID x 4 d + Ceftriaxone 250mg IM x1
Inpatient - IV Doxycycline + 2nd gen Ceph (Cefoxitin or Cefotetan) OR Clindamycin + Gentamicin
Bacterial Vaginosis
MC of vaginitis
D/t Gardnerrella
Sxs
- thin, copious, grey-white “fish” smell
- pH > 5
- clue cells
- Whiff test
Tx Metronidazole PO 500 mg x 7 days or gel 0.75% 5g intravaginally for 5 days or
Clindamycin gel 2% 5g intravaginally or 300mg PO BID x 7 days
Trichomoniasis
D/t Trichomonas vaginalis
Sxs
- malodorous
- frothy, yellow green dc
- Strawberry cervic
- pH > 5
- mobile protozoa
Tx metronidazole 2g PO x1
partner also tx’ed
Candiasis
MC candida albicans
Sxs
- vaginal burning, erythema
- cottage cheese discharge
- pH <4.5 (normal)
- hyphae and yeast on KOH mount
Tx with Flucanozol/Diflucan 150mg PO x 1; another dose if sxs still bad
Miconazole/clotrimazole, terconazole x 7 days vaginal cream
Atrophic Vaginitis
atrophy of vaginal and vulvar tissues d/t hypoestrogenic state
MC in post menopausal women
Sxs
- dryness
- burning
- irritation
- low lubrication
Tx:
1st line therapy for sxs relieve - hormonal vaginal lubricants
Estrogen inserts - vaginal ring w/ 2mg estradiol q 3mos