obesity management

Question 1

Define obesity, and some ways to measure it

Answer 1

excess of body fat

• BMI
• waist circumference
• skinfold measures
• DEXA
• MRI

Question 2

most reliable measure of CVD

Answer 2

waist circumference

Question 3

what waist circumference should men and women be aiming to be under?

Answer 3

<94cm men

<80cm women

Question 4

Adipocytes and inflammation?

Answer 4

adipocytes produce loads of hormones. a lot of these factors causes inflammation

Question 5

What tissue produces leptin?

Answer 5

adipose tissue

Question 6

What tissue makes the hormones: leptin, insulin, GLP-1, oxyntomodulin

Answer 6

leptin - adipose
insulin - pancreas
GLP-1 - GIT
oxyntomodulin - GIT

Question 7

What are 4 drugs that can be used to treat obesity?

Answer 7

Orlistat - intestinal lipase inhibitor
Saxenda - GLP-1 analogue
Sibutramine - acts centrally
Rimonabant - CB1 receptor blocker

Question 8

What surgery can be given to reduce food intake?

Answer 8

bariatric surgery

bypass the bowel

Question 9

What are the NICE Guidelines for bariatric surgery? 6

Answer 9

BMI >40
received treatment in a specialist obesity clinic
tried all other treatments without success
fit enough to have anaesthetic and surgery
absence of specific medical or psychological reasons which could prohibit surgery
understand need for follow-up