obesity + lower GI Flashcards
how is obesity measured
BMI (body mass index)
- body weight in kilos/square of height in meters = BMI
healthy weight range
bmi 18.5 - <25
overweight range
bmi 25 - <30
obesity range
bmi >30
3 categories of bmi
class 1: bmi 30 - <35
class 2: bmi 35 - <40
class 3: bmi >40 (severe obesity)
obesity epidemology (%, prevalence, who, increased risk for (6))
- 70.9% american adults overweight
- prevalence higher in women, African Americans, and hispanic
- those who are less educated, earn less income, more likely to have obesity, reflecting socioeconomic disparities in the disease burden of obesity
- increased risk for disease, disorders, low self esteem, impaired body image, depression, diminished quality of life
causes of obesity (4)
multifactorial
- behavioral
- environmental: not habituated to eat healthy foods
- physiologic
- genetic: family
caloric intake, eating more than calorie expenditure
obesity associated diseases (5)
- 6-20 year decrease in life expectancy
- increased risk cancer: GI, cholerectal
- 10x increase type 2 diabetes
- 4x increase asthma, HTN
- 2x increase alzheimers
tip: CAD, heart, disease, etc. associated with T2DM + HTN
obesity assessment (4) + fact
1) height and weight to determine BMI
- overweight: BMI 25 - 29.9
- obese: BMI exceeding 30
- severe/extreme obese: BMI exceeding 40
2) waist circumference: >35 women, >40 men = increase risk obesity
3) hip to waist ratio: identifies central adiposity (0.65-0.8) -> leads to T2DM, metabolic syndrome -> insulin resistance -> HTN, CAD
4) lab studies: cholesterol, triglycerides, fasting BG (increase insulin resistance), HA1C, liver function test (fatty liver disease d/t fat infiltrates, alcohol steatosis)
FACT: increase adipose tissue (male) causes increase endogenous estrogen (hypercoaguability), leading to testosterone suppression and lose weight
obesity effects: mechanics of ventilation and circulation (5)
- maintain lower fowler position to maximize chest expansion
- continuous pulse ox
- supplemental oxygen
- frequent respiratory assessments (monitor on pulse ox, BMI >50 dont do self, safety for everyone)
- flat = hypoventilation, low oxygen
obesity effects: central and peripheral circulatory compromise (4)
- use appropriately sized BP cuff
- monitor for DVT
- correct medication dose
- pressure injuries
obesity effects: pharmacokinetics & pharmacodynamics (3)
- change with obesity
- understand that some drugs have enhanced effects while others have diminished effects with patients with obesity
- be cognizant that weight based calculations of drug dosages for patients with obesity may be altered
tip: weight based Coumadin -> 400 ibs = thin blood too much, insulin weight based -> 400 ibs = increase d/t resistance
obesity effects: skin integrity and body mechanics (3)
- assess for pressure ulcers
- speciality bariatric equipment
- Hoyer lift
obesity management (4)
- lifestyle modifications
- pharmacologic
- non surgical
- surgical
obesity lifestyle modifications (7)
- aimed at weight loss and maintenance
- setting weight loss goals -> realistic, long term, difficult to maintain
- improving diet habits -> global health improvement, weight watchers
- increase physical activity
- addressing barriers to change
- self monitoring and strategizing ongoing lifestyle changes aimed at a healthy weight
- health sleep habits
obesity pharmacologics (2)
- aimed to supplement (NOT REPLACE) det and exercise
- indicated for BMI >30 or BMI >27 with related conditions (T2DM, HTN)
obesity pharmacology meds (4 main)
1) orlistat (Xenical)
2) phentermine-toprimate (Qysmia)
3) naltrexone-burpion (contrave)
4) lirglutide (saxenda)
orlistat (xenical) (function, adr, tip)
function: reduces GI absorption of fat (small bowel)
ADRs: diarrhea, gas, stomach pain, liver injury (not common)
phentermin-topiramate (Qysmia) (function, adr, tip)
function: appetite suppressant
ADR: constipation, dizziness, dry mouth, insomnia
TIP: teratogenic and can exacerbate heart conditions
no HTN, no pregnancy
naltrexone-buprion (Contrave) (function, adr, tip)
function: increases satiety, reduces appetite (antipsychotic agent, opioid withdrawal)
ADR: constipation, dizziness, dry mouth, insomnia
TIP: may cause suicidal ideation, high BP
no HTN
liraglutide (saxenda) (function, adr, tip)
function: mimics GLP - 1 (glycogen like peptide 1) to curb appetite
ADR: nausea, diarrhea, constipation, increased HR.
TIP: risk of pancreatitis, marketed at lower dose as Victoza (T2DM treatment)
obesity non surgical (2)
- minimally invasive interventions
1) vagal blocking
- blocking of vagus nerve via implanted device (thoracic cavity)
- few side effects (decrease BF to gut -> decrease appetite)
2) intragastric balloon therapy (gastric bypass)
- endoscopic placement of saline filled balloon to fill up space in gut
- remains in place for 3-6 months
- adverse effects: N/V, balloon rupture causing obstruction
obesity surgical (bariatric surgery) (4)
- results in weight loss of 10-35% body weight within 2-3 years
- improvement in comorbid conditions
- selection by multidisciplinary team
- selection criteria has changed to include BMI of 30 for patients with comorbid conditions (types depends on patient)
obesity bariatric surgery (4)
- roux en-Y gastric bypass
- gastric banding
- sleeve gastrectomy
- bilipancrgatic diversion with duodenal switch
roux en-Y gastric bypass (2)
- connecting roux limb of jejunum (small intestine) to pouch in stomach (that is reduced in size to decrease caloric and nutrient absorption)
- not ideal or popular globally due to physiological changes
gastric banding (3)
- inflatable silicone band creating false cavity to decrease appetite
- a prosthetic device is used to restrict oral intake by creating a small pouch of 10-15 mL that empties through the narrow outlet into the remainder of the stomach
- 2nd most common, can remove and go back to normal
sleeve gastrectomy (3)
- most popular today (80%)
- making smaller stomach to decrease appetite and early satiety
- if overeat, can stretch stomach
bariatric surgery - preop considerations (6)
preoperative care: education and counseling
- risks and benefits of surgery
- complications
- post surgical outcomes
- dietary changes (way before surgery)
- lifelong follow up
- lab testing
complications of bariatric surgery (6)
- hemorhage
- venous thromboembolism (DVT, PE)
- bile reflux
- dumping syndrome: constant diarrhea due to bypass of normal gut path (electrolytes -> malabsorption)
- dysphagia
- bowel or gastric outlet obstruction