Obesity Flashcards
Define obesity
BMI > 30
Define obesity
BMI > 30
Genetic factors that affect ‘energy out’?
Muscle mass
Mitochondrial function
What are some important weight Hx questions?
- When did weight gain begin?
- What has been the trajectory of your weight?
- earlier the onset of obesity, the less treatable by intervention
What does obesity
Genetic factors that affect ‘energy out’?
Muscle mass
Mitochondrial function
What are some important weight Hx questions?
- When did weight gain begin?
- What has been the trajectory of your weight?
- earlier the onset of obesity, the less treatable by intervention
What does obesity
What are some important weight gain Hx questions?
A. Cause of weight gain:
- When did weight gain begin?
- What has been the trajectory of your weight?
- earlier the onset of obesity, the less treatable by intervention
B. Consequence of weight gain:
- T2DM
- HTN
- Arterial disease: IHD, stroke
- Hepatic steatosis
- Sleep apnoea
- Lithiasis (kidney stones)
- Gout (hyperuracaemia) - early onset
- OA
- F: PCOS, infertility
- M: androgen deficiency
- Mental health: depression,
- Cancer: due to chronic inflammatory state
What does obesity
What are some important weight gain Hx questions?
A. Cause of weight gain:
- When did weight gain begin?
- What has been the trajectory of your weight?
- earlier the onset of obesity, the less treatable by intervention
B. Consequence of weight gain:
- T2DM
- HTN
- Arterial disease: IHD, stroke
- Hepatic steatosis
- Sleep apnoea
- Lithiasis (kidney stones)
- Gout (hyperuracaemia) - early onset
- OA
- F: PCOS, infertility
- M: androgen deficiency
- Mental health: depression, anxiety
- Cancer: due to chronic inflammatory state
What does obesity
What are some important weight gain Hx questions?
A. Cause of weight gain:
- When did weight gain begin?
- What has been the trajectory of your weight?
- earlier the onset of obesity, the less treatable by intervention
B. Consequence of weight gain:
- T2DM
- HTN
- Arterial disease: IHD, stroke
- Hepatic steatosis
- Sleep apnoea
- Lithiasis (kidney stones)
- Gout (hyperuracaemia) - early onset
- OA
- F: PCOS, infertility
- M: androgen deficiency
- Mental health: depression, anxiety
- Cancer: due to chronic inflammatory state
- GORD
What does obesity
Pathophysiology of central adiposity?
Visceral and peri-visceral fat
Pathophysiology of central adiposity?
Visceral and peri-visceral fat
Normal waist circumference of M
Normal waist circumference of F
What is metabolic syndrome?
3 or more of:
- central (abdominal) obesity
- HTN
- high blood triglycerides
- low levels of high density lipoproteins (HDL)
- impaired fasting glucose (IFG) or diabetes
Normal waist circumference of F
What is metabolic syndrome?
3 or more of:
- central (abdominal) obesity
- HTN
- high blood triglycerides
- low levels of high density lipoproteins (HDL)
- impaired fasting glucose (IFG) or diabetes
What is the consequence of aggressive weight loss strategy?
Must do physical activity to preserve muscle mass when dieting - determines large amount of energy expenditure
If aggressive weight loss without muscle mass preservation, worse off than before
Why do males normally have more visceral adiposity than females?
On average, females have greater subcutaneous fat stores compared to men.
Therefore less prone to having visceral adiposity even with similar BMI.
Why do males normally have more visceral adiposity than females?
On average, females have greater subcutaneous fat stores compared to men.
Therefore less prone to having visceral adiposity even with similar BMI.
*indigenous population have less subcutaneous stores - therefore higher T2DM, obesity
