obesity Flashcards
how many adults are obese/overweight?
nearly 3/4s
children
projected to have shorter life span than parents
healthy people 2030
decrease obesity to 15.5%
why does body size matter?
extra weight:
decreases: QOL, fertility, work performance, sleep time and quality
increases: aging, premature death, CVD, clots, DM
BMI
overweight: 25-29.9
obese: 30+
which of the following types of fat has implicated as most harmful due to increased inflammation, release of FFA, etc.
visceral fat
inflammation
adipose tissue: active endocrine organ
silent inflammation: associated with excessive visceral fat
adipocytokines: pro-inflammatory + antinflammatory factors –> TNF-a, adiponectin, leptin
non-sickness
simply surviving
not in a healthy state of thriving
obesity contributing factors
behavioral factors –> most contributing
genetics
today: never ending responsibilities, longer hours, sedentary lifestyle
no breakfast
high glycemic carbs
refined sugars
weight loss
calories in - calories out
macros
protein - 4 10-35%
carbs - 4 40-65%
fat - 9 20-35%
alcohol - 7
glycemic index
how fast blood sugar increases after eating a certain food
empty calories
cals from solid fats + added sugars
solid fats
solid at room temp
butter, beef fat, shortening
weight loss
high fiber, high protein
lower carb, lower fat
physical activity
reduces body fat and increases muscle
reduces risk of heart disease, stroke, T2DM, obesity
physical activity
more than 80% of adults do note meet guidelines for both aerobic and muscle stregnthening activities
behavioral therapy
self-monitoring
medication therapy
CNS stimulants: phentermine, phendimetrazine, benzphentermine, diethylproprion
Lipase inhibitor: orlistat
GLP1: liraglutide, semaglutide
opioid antago: naltrexone + buproprion
surgery
gastric bypass: reduces gastric volume so food bypasses most of upper GI
sleeve gastrectomy: 80-85% of stomach removed –> reduces gastric volume
surgery clinical implications
routine nutritional supplementation
five to six small meals a day
altered drug absorption: enteric coated + sustained release change to IR