ID Flashcards
COVID-19
older at risk
comorbidities: cancer, CKD, COPD, asthma
viral shedding: can culture live virus
COVID 19 guideline
glucocorticoids
recommends dexamethasone opposed to no dexamethasone
inhaled glucocorticoids: for mild-to-moderate COVID19
IL-6 inhibitors: tocilizumab
remdesivir
paxlovid (nirmatrelvir/rotinavir)
dexamethasone in COVID19
effictive in increasing mortality with patients on oxygen
remdesivir
suggest to start within 7 days of symptom onset
paxlovid
suggests to start within 5 days of symptom onset
mpox
rare disease by monkeypox virus; endemic in africa
signs: rash, spots, red, many spots
mpox demographics
median 38 yo
99% male
75% white
96% homosexual
tecovirimat
TPOXX use to treat mpox
STIs
chlamydia
gonorrhea
syphilis
chlamydia treatment
recommended: doxycycline 100mg BID 7 Days
alternative: 1 gram azithromycin or levofloxacin 500 mg QD 7 days
urethra, cervix, rectum: ceftriaxone 500mg IM for <150kg
syphilis treatment
secondary recommendeation: benzathine penicillin 2.4m units IM or doxy 100mg PO BID 14 d
latent recommendations: early - benz penicillin or doxy 100 BID 14 days
late - benz penicillin or doxy 100 BID 28 days
alexander fleming warning
bacteria will become resistant to penicillin
intrinsic resistance
always resistant to given antibiotic
acquired resistance
organisms susceptible to drug that become resistant
occurs due to a change in bacterial DNA (mutation)
resitance - types of genetic exchange
conjugation - direct contact/mating via sex pili
transduction - genes transfered between bacteria
transformation - the transfer or uptake of free flaoting DNA
