Ob-Gyn Brainscape Flashcards - uWise Abnl Obstetrics

1
Q

MTX tx pre-reqs for (suspected) ectopic?

A

stable, not ruptured, mass <3.5 w/ FHR), nl LFTs, nl BUN/Cr, nl white count, able to f/u

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2
Q

define: recurrent abortion

A

refers to three successive spontaneous abortions

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3
Q

define: missed abortion

A

fetal demise without cervical dilatation or passage of products of conception

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4
Q

define: incomplete abortion

A

passed some, but not all, of the products of conception

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5
Q

When should a cerclage be placed in a woman w/ a h/o cervical insufficiency?

A

14 weeks GWA

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6
Q

Use of ACE inhibitors during pregnancy causes?

A

oligohydramnios, fetal growth retardation and neonatal renal failure, hypotension, pulmonary hypoplasia, joint contractures and death

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7
Q

Timing of glucose challenge?

A

patients of average risk screening is performed at 24 – 28 weeks while those at high risk (severe obesity and strong family history) screening should be done as soon as feasible.

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8
Q

SSRI contraindicated in preg?

A

paroxetine

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9
Q

First line imaging for suspected appendicitis in preg?

A

graded compression u/s

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10
Q

Percentage of women w/ gHTN who will go on to develop Pre-E?

A

25%

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11
Q

protein cut-offs for Pre-E and E?

A

> 300mg/day = mild; 5000mg/day (i.e. 5g/d) = severe

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12
Q

What is a therapeutic mag level for tx of pre-eclampsia?

A

between 4-7 mEq/L.

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13
Q

Contraindications to expectant mgmt for severe Pre-E remote from term?

A

thrombocytopenia, maxed out on 2 BP agents w/o ctrl, non-reassuring fetal surveillance, LFTs > 2X nl, eclampsia, persistent CNS sx and oliguria

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14
Q

HELLP stands for?

A

hemolysis, elevated liver enzymes & low plts

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15
Q

When to start anti-HTNive in preg?

A

pressures persistently greater than 160 systolic and 105 diastolic

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16
Q

Goal diastolic in anti-HTNive tx in preg?

A

90-100 mmHg

17
Q

First line agents and dosing for HTN in preg?

A

hydralazine (a direct vasodilator) 5 mg IV followed by 5-10 mg doses IV at q20-min (maximum dose = 40 mg); or labetalol (combined alpha & beta antagonist) 10-20 mg IV followed by 20 mg, then 40 mg, then 80 mg IV q10-min (maximum dose = 220 mg)

18
Q

Non-invasive test of fetal anemia?

A

Middle cerebral artery peak systolic velocity

19
Q

What is the ratio of RhoGAM to # of cc’s of fetal blood neutralize?

A

10mcg : 1 cc

20
Q

Current recommendation for RhoGAM prophylaxis?

A

Rh- women w/o evidence of Rh immunization is prophylactically at 28-wks (after an indirect Coombs’ test) and w/in 72hrs of: delivering an Rh+ baby, OR following spontaneous OR induced abortion, following antepartum hemorrhage and following amniocentesis or chorionic villus sampling

21
Q

Test to determine amount of fetal blood that entered mother’s bloodstream s/p abruption?

A

Kleihauer-Betke test

22
Q

What is seen in the amniotic fluid of a fetus w/ erythroblastosis fetalis?

A

bilirubin, can do OD test to determine [bili] and thus severity of crisis

23
Q

Placentation and amniotic sacs in monozygotic twins

A

If division occurs on post-conception days 1-3 (pre-morula) –> monochorionic monoamniotic; days 4-8 –> monochorionic diamniotic; days 9+ dichorionic diamniotic

24
Q

Placentation and amniotic sacs in dizygotic twins

A

Always dichorionic diamniotic

25
Q

TTTS usually occurs in ___chorionic ___amniotic twins

A

monochorionic, diamniotic

26
Q

Stages of grief

A

Denial, Anger, Bargaining, Depression, Acceptance

27
Q

W/u for a woman who has had fetal demise of one fetus in a multiple gestation?

A

Check maternal serum fibrinogen level, maybe low –> coagulopathy (ask about nose bleeds, etc.)

28
Q

Risk factors for breech presentation?

A

fibroids and other uterine anomalies, polyhydramnios, prematurity, multiples, anencephaly, hydrocephaly, previa, genetic d/o

29
Q

Fetal fibronectin PPV vs NPV

A

Higher NPV: “negative fetal fibronectin test gives a more than 95% likelihood of remaining undelivered for the next 2 weeks” [Wiki]

30
Q

S/Sx of mag tox by mag level

A

High levels of magnesium sulfate may cause respiratory depression (12-15 mg/dl) or cardiac depression (>15 mg/dl). Prior to developing respiratory depression the patient should have diminished or absent deep tendon reflexes (areflexia).

31
Q

It is especially important not to use indomethacin as a tocolytic after ___ weeks gestation

A

32

32
Q

Benefits of betamethasone treatment in pre-term fetuses

A

incr pulm maturity and decr RDS incidence/severity. also assoc’d w/ decr intracerebral hemorrhage and necrotizing enterocolitis

33
Q

When is tx w/ betamethasone appropriate?

A

24-34 weeks gestation

34
Q

The presence of fFN in the cervical mucus between __ and __ weeks is thought to
indicate a disruption or injury to the maternal-fetal interface.

A

22 and 34

35
Q

Prostaglandin F2-alpha is contrindicated in?

A

(a.k.a. hemabate) contraindicated in asthma pts b/c in addition to SMM constriction it bronchoconstricts

36
Q

Methergine (Methylergonovine) is contraindicated in who?

A

women w/ PIH or Pre-E/Ecc b/c in addition to uterotonic it’s also a vasoconstrictor

37
Q

Risks of antepartum SSRI use to fetus?

A

SRIs has been associated with persistent pulmonary hypertension of the newborn and a self-limiting neonatal behavioral syndrome. SSRI use in late pregnancy may be associated with clinical manifestations in as many as 30% of neonates. The clinical manifestations may include respiratory, neurobehavioral, somatic and gastrointestinal symptoms. Neonates may experience hyperirritability, hypertonus and jitteriness.

38
Q

Appropriateness criteria for an operative delivery

A

complete cervical dilation, head engagement, vertex presentation, clinical assessment of fetal size and maternal pelvis, known position of the fetal head, adequate maternal pain control and rupture of membranes

39
Q

When is CVS done?

A

between 10 and 12 weeks gestation