OB Flashcards
DDx 3rd trimester bleeding
Placenta previa
Abruption
Less commonly polyps, cancer, rupture, vasa previa
Risk factors for uterine rupture
Scars from previous c-section Use of prostaglandins Uterine trauma Breech version Extraction Placenta perceta
Signs of uterine rupture
Most common is fetal distress Hypotension Bleeding Abdominal pain Change in contour of abdomen
What are options to control peripartum hemorrhage?
After uterotonics like oxytocin, hemabate, methergine, misoprostol, Cell saver
Uterine ballon Uterine artery embolization Iliac or uterine artery ligation B-lunch suture Hysterectomy
Risk factors for PPH
Uterine atony High birthweight Labor induction and augmentation Chorio Mag sulfate Previous PPH
Anesthetic considerations with hx IVDU in pregnant patient
Poor IV access Hepatitis/HIV Dependence/withdrawal symptoms Uncontrolled HTN —> abruption, PPH Tachycardia, arrthymia MI IUGR IVH
Side effects of Mag therapy
Dec ACH release V - vasodilation, hypotension A - anticonvulsant S - sedative, skeletal muscle relaxant, inc sense to paralytics T - tocolytic
Dec DTR - 4-5 Prolonged PR, ST - 4-7 Somnolence - 5-7 Heart block 12 Resp arrest 15 Death 20
Considerations with pregnant CF patient
Coags (poor vit K abs)
Glucose - gestational DM
Newborns may have intestinal obstruction
How does pregnancy affect MS
Dec relapse, most in 3rd trimester
Inc in first 3 months postpartum
Fetal effects of maternal epilepsy
Fetal hydantoin syndrome
P - Cleft palate, lip
H - Heart defects, hypoplastic face, small head
Fetal asphyxia
Anticoagulation guidelines for neuraxial
UFH 4-6 hours
LMWH 12-24 hours depending on dose
Ticlopidine 14 days
Plavix 7 days
GA has mortality rate 16 times higher than neuraxial
Contraindications to epidural
Refusal Sepsis Hypovolemia Elevated ICP Back injury with deficit Infection at the site Coagulopathy
Hemodynamic changes with pregnancy
Inc fluid volume
Anemia
CO inc 50%, HR, SV inc
Types of vWD
1 - most common, deficiency
2 - qualitative
3 - most severe, absence, hemorrhage
Tx - DDAVP, cryo, FFP, factor concentrate
Considerations with Pre-E
Hypovolemic
Inc SVR
Dec colloid oncotic pressure and permeability —> cerebral and pulm edema
Dec platelet number and function
Mag tx –> dec SVR and inc placental perfusion
Epidural/spinal not working, what would you do?
Depending on time and status of baby
- re-bolus
- re-do - coagulopathy with pre-e?
- local w/ sedation - aspiration risk?
- GA - ? Difficult airway
Emergency C/S with difficult airway, how will you intubate?
Speed and safety are the goals
Optimize mother’s hemodynamics - left uterine, BP normal, has oxygen
Awake fiberoptic
Local infiltration
No time = GA which DI cart, trach kit, induce maintain spontaneous respirations, inc asp risk but losing airway more significant risk
Steps for neonatal resuscitation
Stimulate
PPV if apneic or HR<100
HR<60 - intubate and chest compressions after 30s
Another 30s - Epi 0.01-0.03mg/kg
Hypoglycemia?
Mag toxicity?
Ca —> cerebral calcification and dec survival
Mech for oxytocin, methergine, hemabate
Contraction of uterine smooth muscle through inc intracellular calcium
What is DIC
Activation of coagulation cascade assoc with burns, head trauma, pre-e where there is widespread formation of clots resulting in consumption of clotting factors, thrombocytopenia, hemolytic anemia, diffuse bleeding and thromboembolism.
Inc PT/PTT Fibrinogen <100 Thrombocytopenia Dec ATIII Fibrin degredation products