O2 Binding To Hb Shows Positive Cooperativity Flashcards
1
Q
Hemoglobin exist in two states:
A
T:Tense
R: Relaxed
2
Q
T: Tense
A
Lower oxygen binding affinity
3
Q
R:Relaxed
A
Higher oxygen binding affinity
4
Q
Hemoglobin has 4 hemes
A
4 oxygen molecules
5
Q
Hemoglobin has ______________ cooperativity.
A
Positive
6
Q
Positive cooperativity
A
First binding event increases affinity
-recognized on sigmoidal curve
7
Q
Negative cooperativity
A
Reduces affinity
Not HEMOGLOBIN