O2 Binding To Hb Shows Positive Cooperativity Flashcards

1
Q

Hemoglobin exist in two states:

A

T:Tense
R: Relaxed

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2
Q

T: Tense

A

Lower oxygen binding affinity

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3
Q

R:Relaxed

A

Higher oxygen binding affinity

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4
Q

Hemoglobin has 4 hemes

A

4 oxygen molecules

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5
Q

Hemoglobin has ______________ cooperativity.

A

Positive

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6
Q

Positive cooperativity

A

First binding event increases affinity

-recognized on sigmoidal curve

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7
Q

Negative cooperativity

A

Reduces affinity

Not HEMOGLOBIN

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