O1 Flashcards
Rule of 2 of Meckel’s Diverticulum
2 inches long 2 ft. From ileocecal valve 2% of population 2 years old 2 types of epithelia (gastric, pancreatic)
Opportunistic fungal infections
- Candida
- Aspergillus
- Pneumocystis
- Cryptococcus
Types of collagen
I- bONE
II- carTWOlage
III- 3ticulin (reticulin)
IV- FLOOR (basement membrane)
Glucose transporter
Glut 1: RBC, Brain
Glut 2: pancreas, liver, kidney, small intestine
Glut 4: adipose tissue, skeletal muscle
Types of Medical Fees
- Pakyaw or Straight Fee
- Retainer fee
- Contingent fee
- Simple fee
Cardiac cycle
1. Atrial contraction 2 Isovolumetric contraction 3. Systolic ejection 4. Isovolumertic relaxation 5. Rapid ventricular filling 6. Reduced ventricular filling
Right to left shunts: cyanotic heart disease
- Truncus arteriosus
- Transposition of great vessels
- Tricuspid atresia
- Tetralogy of fallot
- TAPVR
Left to Right shunts
VSD: pansystolic murmur
ASD: fixed split S2
PDA: continuous machinery like murmur
Tetralogy of fallot
- RVH
- Pulmonic valve stenosis
- VSD
- Overriding aorta
Steps in protein synthesis
Initiation -> Elongation -> Termination
Start codon
AUG
Stop codon
UAA
UAG
UGA
Hesselbach’s triangle:
- epigastric vessels
- inguinal ligament
- lateral borders of rectus abdominis
Triangle of Calot:
- cystic duct
- common hepatic duct
- inferior border of the liver
significance: Cystic artery
Types of necrosis
- coagulative
- liquefactive
- casseous
- fatty
- fibrinoid
- gangrenous
Transudate vs. Exudate
Transudate:
• HYPOcellular
• Protein POOR
• SG: < 1.012
• Due to:
1. increased hydrostatic pressure (ex. Heart failure)
2. decreased oncotic pressure (ex. Nephrotic syndrome)
Exudate: • HYPERcellular • Protein RICH • SG: > 1.012 • Due to: 1. inflammation, Cancer, PTB 2. obstruction
Double bubble sign in xray
Duodenal atresia
BILE components
- Lecithin
- Bile acid/ Bilirubin
- Cholesterol
Absorption-> Terminal ileum
Plummer Vinson Syndrome
Dysphagia
Anemia
Glossitis
APPENDICITIS: Stages
- Congestive
- Suppurative
- Gangrenous
- Rupture
PHARMACOKINETICS
What the body does to the drug
- Bioavailability
- Volume of Distribution
- Half life
- Clearance
TUMOR Markers
PSA- Prostate CA-125- ovarian CEA- Colon S-100- neuro AFP- Liver ALP- bone B-HCG- GTD’s CA-15-3- Breast CA 19-9 - Parncreatic
HYPERSENSITIVITY Reaction
I- Anaphylactic (allergic reactions)
II- Immune mediated (goodpasture, ITP)
III- Cell mediated (SLE, Serum sickness, GVHD)
IV- Delayed (GB, Contact derm, TB)
Transplant rejection
HYPERACUTE - within minutes
ACUTE - within weeks
CHRONIC - within months
GVHD - varies
Cell Types:
- Permanent Cells
- Stable (Quiescent) Cells
- Labile cells
5 STAR PHYSICIAN:
- Medical Researcher
- Health Educator
- Health Leader
- Health Care Provider
- Social Mobilizer
5 TYPES OF IMMUNOGLOBULIN:
IgG IgA IgM IgE IgD
Oxygen-hemoglobin dissociation curve
SHIFT TO THE LEFT:
- Decreased temperature
- Decreased altitude
- Decreased pCO2
- Decreased 2,3 DPG
- Fetal Hemoglobin
- INCREASED pH
SHIFT TO THE RIGHT:
- Increased temperature
- Increased altitude
- Increased pCO2
- Increased 2,3 DPG
- DECREASED pH
Gastric Cells and their Secretions:
Mucus cells- Mucus
G cells- Gastrin
Chief cells- pepsinogen
Parietal cells- HCl and IF
10 MEDICINAL PLANTS:
- Sambong: diuretic and anti-urolithiasis
- Akapulko: fungal dermatitis; scabies
- Niyug-niyogan: ascariasis
- Tsaang gubat: abdominal pain
- Ampalaya: DM
- Lagundi: cough and asthma
- Ulasimang bato: anti-gout
- Bayabas: wound cleaning; mouth sore
- Bawang: lowers cholesterol
- Yerba Buena: body ache; pain
SOURCES OF INFECTION IN SURGICAL PATIENTS:
- Indwelling catheter/IV
- UTI, SSS
- Sinusitis
- Clostroidium difficile enteritis
- Diverticulitis
- Perforated PUD
PRIMITIVE REFLEXES:
- Moro reflex
- Rooting reflex
- Sucking reflex
- Palmar and plantar reflex
- Babinski reflex
- Gallant reflex
STRAP MUSCLES:
Sternohyoid
Sternothyroi
Superior body of
omohyoid
HAGMA
MUDPILES
Methanol Uremia DKA Infection, Iron, Isoniazid, Inborn errors of metabolism Lactic acidosis Ethylene glycol Salicylates, Sympathomimetics
NAGMA
HAARDUP
Hyperalimentation Acetazolamide, Amphotericin B Renal Tubular acidosis Diarrhea Ureterosigmoidostomy Pancreatic fistula
MALE AND FEMALE GENITAL HOMOLOGUE
Glans penis- Glans clitoris
Corpus cavernosum and spongiosum- vestibular
bulbs
Bulbourethral glands of Cowper- Greater vestibular
glands of Bartholin
Prostate gland- Urethral and Paraurethral glands
of Skene
Ventral shaft of penis- Labia minora
Scrotum- Labia majora
TOP 5 CAUSES OF ATRIAL FIBRILLATION:
- Ethanol ingestion: Holiday heart syndrome
- Valvular heart disease
- Ischemic heart disease
- Cardiomyopathy
- Thyrotoxicosis
CHARCOT’S TRIAD:
- Fever
- RUQ pain
- Jaundice
Reynold’s Pentad
- Fever
- RUQ pain
- Jaundice
- Change in sensorium
- Hypotension (shock)
BENIGN THYROID DISEASES:
- Grave’s disease
- Plummer’s disease
- Chronic lymphocytic thyroiditis
- Giant cell thyroiditis
MALIGNANT THYROID DISEASES:
- Papillary carcinoma: 80% best prognosis
- Follicular carcinoma: 10% unicentric
- Medullary carcinoma: 5%
- Anaplastic carcinoma: poor prognosis
JONES Criteria for Acute Rheumatic Fever
Major manifestation:
"J"oint - Polyarthritis, migratory O (heart) - Carditis "N"eurologic -sydenham Chorea "E"rythema marginatum "S"ubcutaneous nodules
Minor manifestation:
1. Clinical findings: arthralgia and fever
2. Lab findings: increased Acute phase reactants,
prolonged PR interval
DUKES Criteria for Infective Endocarditis
Major Criteria:
- Positive blood culture results for IE
- Positive echocardiographic study
MINOR criteria:
- Predisposing heart condition
- Fever >38.0C
- Vascular phenomena
ECG:
P wave: atrial depolarization
PR interval: conduction delay through AV node
QRS complex: ventricular depolarization
T wave: ventricular repolarization
ECG changes in MI:
- ST elevation: transmural infarct
- Pathologic Q waves: transmural infarct
- ST depression: subendocardial infarct