O&G contraception Flashcards
Emergency contraception: Levonorgestrel (Levonelle)
- mode of action not fully understood - acts both to stop ovulation and inhibit implantation
- should be taken as soon as possible - efficacy decreases with time
- must be taken within72 hours of unprotected sexual intercourse (UPSI)*
- single dose of levonorgestrel 1.5mg (a progesterone)- the dose should be doubled for those with a BMI >26 or weight over 70kg
- 84% effective is used within 72 hours of UPSI
- levonorgestrel is safe and well-tolerated. Disturbance of the current menstrual cycle is seen in a significant minority of women. Vomiting occurs in around 1%
- ifvomiting occurs within 3 hours then the dose should be repeated
- can be used more than once in a menstrual cycle if clinically indicated
- hormonal contraception can be started immediately after using levornogestrel (Levonelle) for emergency contraception
Emergency contraception: Ulipristal acetate (EllaOne)
- aselective progesterone receptor modulator
- primary mode of action is thought to be inhibition of ovulation
- 30mg oral dose taken as soon as possible, no later than120 hours after intercourse
- concomitant use with levonorgestrel is not recommended
- Ulipristal may reduce the effectiveness of hormonal contraception.Contraception with the pill, patch or ring should be started, or restarted, 5 days after having ulipristal. Barrier methods should be used during this period
- caution should be exercised in patients with severe asthma
- repeated dosing within the same menstrual cycle was previously not recommended - however, this has now changed andulipristal can be used more than once in the same cycle
- breastfeeding should be delayed for one week after taking ulipristal. There are no such restrictions on the use of levonorgestrel
Emergency contraception: copper IUD
- a copper IUD is themost effective method of emergency contraception and should be offered to all womenif they meet the criteria
- if the criteria for insertion of a copper IUD are not met or is not acceptable to the woman, oral emergency contraception should be considered
- in practice the vast majority of women choose oral emergency contraception, but it is important to offer the choice to all women given how effective copper IUDs are
- must be inserted within 5 days of UPSI, or
- if a woman presents after more than 5 days thenan IUD may be fitted up to 5 days after the likely ovulation date
- may inhibit fertilisation or implantation
- prophylactic antibiotics may be given if the patient is considered to be at high-risk of sexually transmitted infection
- is 99% effective regardless of where it is used in the cycle
- may be left in-situ to provide long-term contraception. If the client wishes for the IUD to be removed it should be at least kept in until the next period
- may be offered after this period as long as the client is aware of reduced effectiveness and unlicensed indication
Post partum contraception: POP
Contraception needed ONLY after day 21
- the FSRH advise ‘postpartum women (breastfeeding and non-breastfeeding) canstart the POP at any time postpartum.’
- after day 21 additional contraception should be used for the first 2 days
- a small amount of progestogen enters breast milk but this is not harmful to the infant
Post partum contraception: COCP
- absolutely contraindicated - UKMEC 4 - if breastfeeding < 6 weeks post-partum
- UKMEC 2 - if breastfeeding 6 weeks - 6 months postpartum*
- the COCP may reduce breast milk production in lactating mothers
- should not be used in the first 21 daysdue to the increased venous thromboembolism risk post-partum
- after day 21 additional contraception should be used for the first 7 days
Post partum contraception: lactational amenorrhoea method (LAM)
98% effective providing the woman is fully breast-feeding (no supplementary feeds), amenorrhoeic and < 6 months post-partum
Post partum contraception: IUD/IUS
The intrauterine device or intrauterine system can be inserted within48 hours of childbirth or after 4 weeks
Aninter-pregnancy interval of less than 12 monthsbetween childbirth and conceiving again is associated with an increased risk of preterm birth, low birth weight and small for gestational age babies
Mode of action of contraception: COCP
Inhibits ovulation
Mode of action of contraception: POP
Thickens cervical mucus
Mode of action of contraception: Desogestrel-only pill
Primary: Inhibits ovulationAlso: thickens cervical mucus
Mode of action of contraception: Injectable contraceptive (medroxyprogesterone acetate)
Primary: Inhibits ovulationAlso: thickens cervical mucus
only contraception associated with weight gain officially
Mode of action of contraception: Implantable contraceptive (etonogestrel)
Primary: Inhibits ovulationAlso: thickens cervical mucus
Mode of action of contraception: Intrauterine contraceptive device
Decreases sperm motility and survival
Mode of action of contraception: Intrauterine system (levonorgestrel)
Primary:Prevents endometrial proliferation
Also: Thickens cervical mucus
Method of action of EMERGENCY contraception: Levonorgestrel
Inhibits ovulation