O&G and Breast Flashcards
Uterine fibroids
1. Characteristic MR appearance?
2. Degeneration of fibroid characteristic?
3. Types of degeneration and their imaging appearance?
- Low T1, low T2, variable enhancement
- Involution of blood supply - loss of enhancement
- Hyaline - T2 dark; red (carneous, pregnancy) - T1 bright rim; myxoid - T2 bright
Cervical cancer
1. Key distinction to make on staging?
- Is there parametrial invasion - yes, it’s IIb and you need chemo/rad. No, it’s IIa and you have surgery.
Endometrioma appearance
1. on US?
2. on MR?
3. how to distinguish from haemorrhagic cyst?
- Homogenous, low level internal echoes (snowglobe), increased through transmission
- T1 bright (blood), T2 dark (methaemoglobin), so called “T2 shading”, no loss of signal on fat sat
- Haemorrhagic cyst will resolve in 1-2 cycles
Malignant ovarian neoplasms - top three?
Serous cystadenocarcinoma
Endometroid
Mucinous cystadenocarcinoma
All subtypes of surface endothelial tumour
Miscellaneous ovarian tumours
1. Important fact about struma ovarii?
2. Meig’s syndrome?
- Contain thyroid tissue - patient may be thyrotoxic
- Ascites, pleural effusion, fibroma
3 most important malignant GCTs?
Dysgerminoma
Yolk sac tumour
Embryonal cell ca
On Granulosa cell tumour:
- age of presentation?
- presents with?
- imaging appearance
- usually post-menopausal
- endometrial thickening/PMB due to oestrogen secretion
- solid or cystic, thick septations
On theca cell tumour/thecoma:
- age
- presentation
- imaging
- can present at any age
- precocious puberty, abnormal bleeding, PMB
- solid tumour, T1 and T2 dark
Krukenberg tumours - primary has metastasized to ovary with signet ring cell features - most common primaries?
Stomach
Colorectal
Appendix
HPB
Small bowel
Breast
Lung
Contralateral ovary
Primary cancers that metastasize to ovaries (non-Krukenberg)?
Melanoma
Lymphoma
Leydig-Sertoli cell tumours
- Age?
- Clinical features?
- Tumour marker?
- MRI appearance?
- Teens (premenopausal women)
- Virilisation, excess androgen, infertility
- AFP
- Solid fibrous tumours with areas of cystic change which may include haemorrhage/necrosis - T1/2 dark +/- high signal related to cystic change
Endometrial cancer
- Key staging investigation? Key feature that determines management?
- Cut off for endometrial thickness on US in a post-menopausal woman?
- Are the inguinal nodes regional?
- MR appearance
- MRI with contrast; myometrial invasion (+ LN involvement)
- 5mm
- No
- T1 isointense to endometrium, T2 hyperintense to myometrium, minimal to variable enhancement
Benign breast lesion
- US appearance of fibroadenoma?
- MR appearance of fibroadenoma?
- Mimic of fibroadenoma?
- Oval, circumscribed, homogenous hypoechoic. May have popcorn calcification if patient is postmenopausal
- T2 bright with non-enhancing septa, progressive enhancement Type 1 kinetics
- Phyllodes tumour
Causes of architectural distortion?
Malignancy - ILC, IDC
Post-surgical
Trauma
Radial scar
Fibrocystic change
Fibrosis
Gynae causes of raised AFP?
Yolk sac tumour
Embryonal cell carcinoma
Leydig-Sertoli tumour
Teratoma