O&G Flashcards

1
Q

Hx for pelvic pain

A

SOCRATES
4Ps - PV bleed (+timing), PV discharge, pain, ?pregnancy
GI/urinary Sx

Gynae/menstrual/sexual Hx

Birth Hx
- outcomes

Contraceptive/smear Hx
- coil in situ

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2
Q

Approach to pelvic pain

A

I would investigate with bedside tests, blood tests and imaging.
At the bedside I would check the obs, take a urine sample for dipstick and bHCG, check the BG
I would take a full set of baseline bloods - FBC, U&E, CRP, LFTs, clotting, G&S and serum bHCG
In the first instance I would request a TVUSS, particularly looking for any evidence of a IUP, free fluid,or tubal ectopic.

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3
Q

Management of ectopic

A

Management of ectopic pregnancy is expectant, medical or surgical, according to bHCG, size, symptoms and haemodynamic status.

First I would counsel the patient on their options and provide them with a leaflet.

If HDS, with no sig pain & the fetal pole is <35mm, expectant Rx or medical Rx may be appropriate with according to bHCG, with follow up. (<30=exp, <1500=med)

If HDUS, symptomatic, or if fetal pole is >35mm, surgical management is appropriate. 1st line would be a laparoscopic salpingectomy, salpingotomy if both tubes are damaged.

Patient needs to be followed up with seriel pregnancy tests until they become negative. given advice re: not becoming pregnant for the next 3 months.

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4
Q

Management of miscarriage

A

Management of miscarriage is expectant, medical or surgical, mainly according to patient preference.

First I would counsel the patient on their options and provide them with a leaflet.

Expectant management (HDS, msd<50mm, CRL<30mm, good home suppport)
• 'Waiting for the miscarriage to pass naturally" 
• It can take a few weeks for the miscarriage to pass and women often experience bleeding and cramps in this time
• If expectant management is unsuccessful then medical or surgical management may be offered

“The process can be sped up with medication or surgery”

Medical management:
• ‘Using tablets to help the miscarriage pass more quickly’
• Vaginal misoprostol
○ Prostaglandin analogue, binds to myometrial cells to cause strong myometrial contractions leading to the expulsion of tissue
• Risks - haemorrhage, infection, retained tissue
• Should be given with anti-sickness and pain relief
Also, pregnancy test after 3 weeks and safety net to return if bleeding hasnt started in 24 hours or stopped in 7-14 days.

Surgical management
• ‘Undergoing a surgical procedure under local anesthetic in the clinic or general anaesthetic’
• The two main options are vacuum aspiration or surgical management in theatre. Give anti D.
Vacuum aspiration is done under local anaesthetic as an outpatient.

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5
Q

Management of UPSI (emergency contraception)

A

Options include ulipristal, levonorgestrel and the copper IUD.

Ulipristal (EllaOne) inhibition of ovulation
• single dose taken as soon as possible, no later than 120 hrs. If vomiting occurs within 3 hours, repeat dose.
• don’t use with levonorgestrel
• contraceptive pill/patch or ring should be restarted, 5 days after having Ulipristal - use barrier methods
• caution in severe asthma, better for overweight people
• ulipristal can now be used more than once in the same cycle
• breastfeeding should be delayed for one week after taking ulipristal (fine with levonorgestrel)

Levonorgestrel
• single dose taken ASAP, within 72 hrs (85% effective)
• can be used more than once in a menstrual cycle
• SEs - disturbance of menstrual cycle, breast tenderness, nausea/vomiting - if vomits within 2 hours then the dose should be repeated

Intrauterine device (IUD)
• must be inserted within 5 days (99% effective)
• OR if a women presents after more than 5 days then an IUD may be fitted up to 5 days after the likely ovulation date
• may inhibit fertilisation or implantation
• prophylactic antibiotics may be given if patient is high risk STI
Risks - pain, infection, bleeding, expulsion, migration
**may be left in-situ to provide long-term contraception.
If the client wishes for the IUD to be removed it should be at least kept in until the next period

I’d also like to counsel her on the risk of STI and invite her for a sexual health screen in 2-3 weeks time
I’d also recommend that her current sexual partner receives a sexual health screen.
I would also counsel the patient on long-term contraceptive options such as IUP, IUD, implant, depot injection.

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6
Q

What are the Fraser guidelines?

A
  1. she has sufficient maturity and intelligence to understand the nature and implications of the proposed treatment
  2. she cannot be persuaded to tell her parents or to allow the doctor to tell them
  3. she is very likely to begin or continue having sexual intercourse with or without contraceptive treatment
  4. her physical or mental health is likely to suffer unless she received the advice or treatment

The advice or treatment is in the young person’s best interests.

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7
Q

Options for contraception

A
*User-dependent*
Hormonal 
- CHC - oral, patch, ring
*measure BP and BMI
*UKMEC
- POP

Non-hormonal/barrier

  • Male/female condom
  • Diaphragm
  • Non-user-dependent* i.e. LARC
  • IUD (copper)
  • IUS, implant, depot injection (progesterone)
  • Male/female sterilisation
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8
Q

Approach to menorrhagia

A
Hx: 4Ps (pain, PV bleed, pv discharge, pregnancy), unscheduled bleeding (IMB/PCB), bloating, urinary Sx
?Anaemia
?FLAWS
?Hypothyroidism
FHx: bleeding problems, cancers
Structural = PALM - polyps/PID, adenomyosis, leiomyoma (fibroids), malignancy
Systemic = COEIN - coagulopathy, ovulatory dysfxn (?PCOS, hypothyroid), endometriosis, iatrogenic (copper coil), UNSPECIFIED DUB

I would investigate with bedside tests, blood tests and imaging.
At the bedside I would do full examination + speculum + bimanual, check the obs and take a urine sample for dipstick and bHCG. I also may take vaginal swabs for STIs and consider a cervical smear if not up to date.
I would take a full set of baseline bloods - FBC, U&E, CRP, LFTs, TFTs, and clotting.
In the first instance I would refer to gynae for a TVUSS to assess for local causes. A pipelle biopsy or hysteroscopy may be indicated following this.

Rx: treat the cause
MEDICAL - If needs contraception - IUS – COC
If not - tranexamic acid, mefenamic acid (NSAID)
SURGICAL - endometrial ablation, myomectomy, hysterectomy

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9
Q

Approach to postmenopausal bleeding

A

Hx: 4Ps, unscheduled bleeding (IMB/PCB), bloating, urinary Sx/bowel Sx
**oestrogen exposure - birth Hx, menstrual Hx, PMHx incl cancers, HRT
?Anaemia
?FLAWS
FHx: bleeding problems, cancers

> /= 55 + PMB - REFER FOR 2WW TVUSS

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10
Q

Approach to the menopause

A

Sx:
irregular periods - amenorrhoea
vasomotor - hot flushes, night sweats (disturbs sleep)
urogenital - dryness, itching, dyspareunia
psychological changes - dec mood/libido, irritable

Management
Conservative - lifestyle measures (exercise, relaxation), self-help, stop smoking, reduce alcohol
psychological support, increased lubrication
Medical
- HRT Normally O+P, cyclical if peri menopausal, transdermal patch if obese. SE’s= breast tenderness, nausea, headaches, fluid retention, mood swings.
Risks= VTE, stroke, CHD, breast and ovarian cancer
- vaginal creams if predom vaginal sx
- Non hormonal treatments include clonidine for flushing, beta blockers for palpitations, ssri’s for depression and bisphosphonates for osteoporosis)

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11
Q

Approach to suspected ovarian Ca

A
Red flags
? persistent bloating/IBS
? early satiety/loss of appetite
? pelvic/abdo pain
? inc urinary freq/urgency 
FLAWS

I would investigate with bedside tests, blood tests and imaging.
At the bedside I would do full examination + speculum + bimanual, check the obs and take a urine sample for dipstick and bHCG. I also may take vaginal swabs for STIs and consider a cervical smear if not up to date.
I would take a full set of baseline bloods - FBC, U&E, CRP, LFTs, and CA125 (if 35 IU/ml or greater, I would refer to gynae for ultrasound scan of the abdomen and pelvis).

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12
Q

Approach to suspected cervical Ca

A

Sx: routine screening, bleeding (PCB), dyspareunia, bloody discharge, foul smelling, pelvic pain.
FLAWS
DDx: ectropion, polyp, cervicitis, pregnancy

At the bedside I would do full examination + speculum + bimanual. check the obs and take a urine sample for dipstick and bHCG. I also may take vaginal swabs for STIs.
If the appearance of the cervix was suspicious for cancer, I’d refer this patient to colposcopy clinic on a 2WW. Here they have a magnified view of the cervix, use acetic acid to stain and take a biopsy.
If Dx is confirmed, the patient will sent to the gynae cancer MDT. Further imaging, CT CAP +/- MRI.
Surgery, chemo, radio
? fertility preservation - trachelectomy - cervix and upper vagina
radical abdominal hysterectomy + BSO + vaginal + lymph nodes

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13
Q

Approach to NVP

A
DDx: 
GI causes
- cholecystitis, appendicitis, pancreatitis
- gastroenteritis
UTI
DKA
Drug reaction
*NVP*
RFs
- multiple preg
- molar preg
- obesity
- nulliparity

Hyperemesis triad

  1. > 5% wt loss
  2. electrolyte disturbance
  3. severe dehydration/ketonuria

I would investigate with bedside and blood tests.
At the bedside I would do full examination & assess fluid status, weigh the patient, check the obs and take a urine sample for dipstick and bHCG. I would take a full set of baseline bloods - FBC, U&E, CRP, LFTs. I would consider an USS ?molar ?multiple.

PUQE score and assess wellbeing
3-12 + no comps - community antiemetics (cyclizine), lifestyle
>13 + no comps - ambulatory care with hydration, antiemetics, thiamine
if complications - inpatients + MDT Rx, VTE prophylaxis, ?steroids

Complications
Maternal - electrolyte abn, GORD, Wernicke’s, MW tear
Foetal - SGA

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14
Q

Incontinence

A

stress? urge? or mixed?
In history ask for age, no of vaginal deliveries?forceps, obesity, pelvic surgery, smoking, diabetes

Ix- urine dipstick at bedside, ask pt to keep a bladder diary, uss bladder and post micturition scan (?retention) Gold standard= urodynamic studies. May consider CT urogram with methylene dye contrast to assess urethral integrity

Urge
C- 1st line- Lose weight, avoid caffeine or artificial flavours. Limit fluids to 1.5l/day. Bladder retraining for 6 wks to increase intervals between voiding.
M- Oxybutynin/ Tolterodine. Mirabegron if worried about anticholinergic side effects.
S- Botox injections, PTNS(percut tibial nerve stim) or SNS (sacral nerve stim)

Stress
C- 1st line- Pelvic floor training (8 contrac, tds for 3 months)
S- 2nd line- retropubic mid-urethral tape procedure, Burch colposuspension
M- 3rd line/unwilling or unsuitable for surgery- Duloxetine

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15
Q

Subfertility

A

In Hx ask about

  • how long have they been trying? How often do they have sex per week? Any difficulties i.e. vaginismus or dyspareunia
  • Periods regular? menorrhagia? dysmenorrhea? previous STI’s, previous pelvic surgeries or chemo? miscarriages or terminations? any children with previous partners? discharge or pain?

Ix- bimanual and speculum examination.
Bloods- Day 2 FSH and Mid luteal prog (day 21), AMH, TFTs, prolactin, testosterone
Imaging- TVUSS, tubal assessment with hysterosalpingogram
Semen analysis

Mx- wait for 2 years of regular sex. 
Medical- clomiphene for ovarian stimulation
Intrauterine insemination
Donor insemination
IVF
Donor egg with IVF

Surgical- for structural causes e.g. adhesions, endometriosis, fibroids, ovarian drilling (PCOS),

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16
Q

Dysmenorrhoea

A

Hx- menarche, always painful or recent change, menorrhagia? sexual history- pelvic pain, dyspareunia, funky discharge

Ix- bimanual+spec
TVUSS

Could be primary (caused by usual prostaglandins)
or secondary (PID, endometriosis, fibroids)

Mx
Primary- NSAIDs, hot water bottle, hormonal contraception, TENS
Secondary- refer to gynae, depends on cause

Endometriosis “condition where tissue that lines the womb starts appearing outside”
RFs= early menarche, fam history, nulliparity, prolonged menstruation, short cycles.
Ix= tvuss, gs=laproscopy to look for chocolate cysts

Mx
M- 1st line=NSAIDs plus COCP, could use POP
S- laproscopy with excision of cysts and ablation of peritoneal deposits. If have completed family, hysteroscopy and oophrectomy.

17
Q

What are the causes of amenorrhoea?

A

Primary causes
Genetic: Turner’s, Mullerian agenesis​
Malformations – imperforate hymen; transverse septum​

Secondary causes​
Contraception​
Pregnancy/ breastfeeding​
Menopause​
Anorexia​
Endo: Cushing’s, hypo/hyperthyroidism, hyperprolactinaemia, congenital adrenal hyperplasia​
PCOS​
Drugs: antipsychotics, anti-emetics e.g. metoclopramide, strong painkillers

PCOS = diagnosis if 2/3 present​
Oligo/anovulation (> 2 years)
Clinical or biochemical features of hyperandrogenism e.g. acne, hirsutism, thinning of scalp hair, weight gain​
Polycystic ovaries on US

Rx:
Conservative​ - Weight reduction, exercise, diet

If not planning pregnancy:
Medical​ - Hormonal contraceptive – if amenorrhoea or DUB. Withdrawal bleed should be every 3-4 mo.​
2nd line - Metformin​

If planning pregnancy:​
Medical​ - Clomiphene 1st line w/ normal BMI (SERM); used for up to 6 mo. Increased risk of multiple pregnancy. +/- metformin (usually added after 3 cycles of failed clomiphene)​
Surgical​ - laparoscopic ovarian drilling to trigger ovulation

18
Q

How would you investigte and manage hyperemesis gravidarum

A

Triad- 5% pre pregnancy weight loss, severe dehydration (?ketonuria) and electrolyte imbalance

Ix
Bedside- Examination for signs of dehydration, urine dip for ketones, MSU for infection, ?stool culture
Bloods- FBC, U&E’s, LFTs, CRP
Imaging- TVUSS to investigate multiple or molar pregnancy

Mx
May need to be admitted (?home suppport). Can also be a candidate for ambulatory fluids and management. Calculate PUQE score to grade severity.

C- bedrest, fluid resuscitation, small but frequent meals, avoid food triggers, dietician review for enteral/parental nutrition
M- Antiemetics ( po or iv cyclizine), thiamine supplementation, thromboprophylaxis (?LMWH)

DDX= GI-gastroenteritis/appendicitis, neuro-raised ICP, ENT-labrynthitus, preeclampsia

19
Q

How might a pt with pre eclampsia present. Ix and Mx?

A

BP>140/90 at 20 weeks + proteinuria (>0.3g/day)
~ incomplete trophoblastic invasion = vascular permeability
Sx- headaches, proteinuria, sudden onset peripheral oedema, vision disturbance, epigastric pain, HELLP (haemolysis, elevated liver enzymes, low platelets) –> eclampsia

Ix-
Bedside- manual BP on both arms, urine dip and MC&S
Bloods- FBC, LFTs, U&Es and clotting
Imaging- Uss to assess foatus and fluid, umbilical artery doppler

Mx
C- Close monitoring with BP 4x daily, with reg bloods (3/week if mod, 2/week if mild), foetal surveillance with uss or umbilical artery dopplers as early delivery may be indicated
M- Treat HTN with labetalol, nifedipine, methydopa.
risk of eclampsia i.e. hyperreflexia - give mg sulphate bolus + infusion (monitor ECG)

More common in- nulliparous women, previous Hx, extremes of maternal age, FHx, large placenta, DM<
Risk to baby- early delivery, reduced placental function, IUGR, stillbirth, placental abruption
Risks to mother- sx and acute liver failure

20
Q

How would you manage this pt with gestational diabetes

A

Diagnosed if FG>5.5mmol/l or 2 hour pasma OGTT>7.8mmol/l

Ix
Bedside- urine dip, OGTT
Bloods- FBC, U&E’s, HBA1c

Mx
C- Diet/exercise, blood sugar diary- follow up in 2 weeks
M- Metformin +/- insulin

Follow up in joint diabetes and antenatal clinic every 2 weeks plus 4 weekly uss growth scans. BM targets= 5.3 pre prandial, 7.8 1 hour post pran and 6.7 2 hour post pran.

Risks to baby- congenital defects, preterm labour, macrosomia, polyhydramnios, dystocia and birth trauma, sudden death and foetal distress

Risks to mother- delayed wound healing post birth, pre eclampsia and HTN, Renal an neuro complications, instrumental delivery

Routinely screen if-
BMI>30
not white
previous macrosomic baby >4.5kg
1st deg relative had it
unexplained still birth
polyhydramnios
glycosuria
21
Q

How would you manage this pregnant women with PV bleeding

A

DDx- placenta praevia, placental abruption, vasa praevia, molar pregnancy, miscarriage, cervical ectropion, trauma, bloody show

Ix- A-E approach
Bedside- Obs (?hypotensive). Examine abdomen (?woody) and do a speculum exam (? blood coming out of os, os open?, ectropion?)
Bloods- FBC, Clotting, G+S and X match, Kleihauer test
Imaging- TVUSS (?praevia), CTG and TAUSS if later

Mx of placental abruption (painful bleeding ~ preeclampsia, cocaine/smoking, trauma, older mother)
If mother in shock - EMERGENCY- c section.
Generally:
*Fetus alive and < 36 weeks
- fetal distress: immediate caesarean
- no fetal distress: observe closely, steroids, no tocolysis,
*Fetus alive and > 36 weeks
- fetal distress: immediate caesarean
- no fetal distress: deliver vaginally
*Fetus dead = induce vaginal delivery
iv fluids, 4 units blood, Anti-D if Rh -ve. If <37 weeks, dexamethasone, if <32 then magnesium sulphate.

Mx of placenta praevia (painless)
Def: Placenta over internal os >16/40 wks

If bleeding, baby need monitoring with a CTG, growth scan and umb dopplers evry 2 weeks. USS at 36 wks to determine method of delivery.
Mx= ABC, iv fluids, blood, steroids if (24-34+6 wks). If major bleeding, admit from 34 wks.

If symptomatic, do a TVUSS and abdo exam. Avoid sex, rescan at 32/40, safety net about bleeding sx

22
Q

Management of PID

A

Outpatient:​

IM Ceftriaxone 500mg​
PO Doxycycline 100mg BD and metronidazole 400mg BD​

Consider removal of IUD if in situ​
Avoid sex until course complete

If pyrexial or PO mx failed, IV Cefoxitin + doxycycline​

STI screening and contact tracing – chlamydia and gonorrhoea​

Follow up: 3 days and 2-4 weeks​

Risks of PID: infertility, ectopic pregnancy, chronic pelvic pain

23
Q

Mx of PE in pregnancy

A

All pts with signs of a PE must have an ECG and a CXR.

If signs of DVT present, do a compression duplex uss. If positive- treat!

If no signs of a DVT are present, do a VQ scan.

If CXR was abnormal, do a CTPA over a V/Q scan.

If clinical suspicion remains high depsite tests, continue anticoagulating.

V/Q= increased risk of childhood cancer, but CTPA= increased risk of breast cancer.

24
Q

How would you manage this pregnant women with PV bleeding

A

DDx- placeta praevia, placental abruption, vasa praevia, molar pregnancy, miscarriage, cervical ectropion, trauma, bloody show

Ix- A-E approach
Bedside- Obs (?hypotensive). Examine abdomen (?woody) and do a speculum exam (? blood coming out of os, os open?, ectropion?)
Bloods- FBC, Clotting, G+S and X match, Kleihaur Betke test
Imaging- CTG,

25
Q

Mx of DVT in pregnancy

A

If signs or sx of VTE, do a duplex uss, LMWH and compression stockings.

If duplex -ve and low clin suspicion, discontinue LMWH. If -ve and high suspicion, continue LMWH and repeat uss in 1 week.

26
Q

Mx of PE in pregnancy

A

If pt has signs and

27
Q

PPH

A

Postpartum haemorrhage (PPH) is defined as blood loss of > 500mls and may be primary or secondary

Primary PPH =within 24 hours
most common cause of PPH is uterine atony (90% of cases). Other causes: tissue, trauma, thrombin

RFs: previous PPH
prolonged labour, pre-eclampsia, older mum,
polyhydramnios, emerg CS, placenta praevia, placenta accreta, macrosomia

Rx: ABC including 2x 14 gauge, CALL FOR HELP ?OBS CALL
IV syntocinon (oxytocin) 10 units or IV ergometrine 500 micrograms
IM carboprost
Fluids/blood products
–> surgical options
- intrauterine balloon tamponade for uterine atony, B-Lynch suture, artery ligation of the uterine arteries.
- hysterectomy is sometimes performed as a life-saving procedure

Secondary PPH = between 24 hours - 12 weeks due to retained placental tissue or endometritis
Rx: swabs/start Abx
or USS to Ix RPoC - surgical evacuation