Nutrition Planning & Intervention Flashcards
Hormones involved in renal function
1) vasopressin (ADH): from hypothalamus (stored in pituitary) exerts pressor effect, elevates BP, increases water reabsorption from distal and collecting tubules
2) renin: vasoconstrictor, secreted by glomerulus when blood volume decreases, stimulates aldosterone to increase sodium absorption and return blood pressure to normal
3) erythropoietin (EPO): produced by kidney, stimulates bone marrow to produce RBC
Labs tests in renal disease
decreased glomerular filtration rate, creatinine clearance
BUN creatinine ratio of > 20:1 indicates a “pre-renal” state in with BUN reabsorption is incr due to acute kidney damage (possibly no dialysis)
BUN creatinine ratio of < 10:1 suggests reduced BUN reabsorption due to renal damage (may need dialysis)
Renal calculi
1.5-2 L/day needed to dilute urine
Nephrosis- nephrotic syndrome
defects in capillary basement membrane of glomerulus which permits escape of large amounts of protein into the filtrate moving through tubules
1) albuminuria, edema, malnutrition, hyperlipidemia (incr synthesis, decr clearance of VLDL)
2) modest protein restriction: .8-1.0 g/kg; 50% from HBV, excess protein will be catabolized to urea and excreted
3) 30% fat, low sat fat, 200 mg chol
chronic kidney disease (CKD)
protein restricted when GFR ml/min falls
Stage 1 & 2: 0.8-1.4 g/kg
Stage 3 & 4: 0.6-0.8 g/kg
Phos
Stage 1 & 2: maintain normal serum level
Stage 3 & 4: 800-1k mg/day or 10-12 mg/g protein
Chronic renal failure: hemodialysis
1.2g prot/kg SBW (standard body wt) at least 50% HBV
<60 y 35 kcal/kg, >=60 y/o or obese 30-35 kcal/kg
Chronic renal failure: peritoneal dialysis
1.2- 1.3g prot/kg SBW (standard body wt) or adjusted BW, at least 50% HBV
<60 y 35 kcal/kg, >=60 y/o or obese 30-35 kcal/kg
Diabetes mellitus
Normal BG: 70-100 mg/dl (post prandial) < 140
Diabetes fasting glucose >=126 or glucose tolerance test >=200
GTT: normal curve is sloped, diabetic curve is rounded
HbA1c goal for diabetics: <7% (normal is <5.7%)
Self management goals:
1) maintain normal BG
2) optimal serum lipid levels (LDL <100, TG<150, HDL>40M >50F)
3) blood pressure goals: systolic <130, diastolic <80
4) prevent and treat chronic complications
Gestational diabetes
risk factors:
BMI >30
h/o GDM
Carb counting
(review manual)
one choice from starch, fruit or milk list= 15g CHO and each is a choice; meal plan outlines the number of CHO choices to be selected for meals and snacks
Insulin
BOLUS:
- rapid-acting (novolog, humalog): take 5-15 min before eating, usual duration 4 hours
- short-acting/regular (humilin): take 30-45 min before meal (burst of insulin to cover the meal just abotu to be eaten) one unit covers 10-15g CHO; duration 3-6 hours
BASAL/BACKGROUND:
- intermediate acting (humilin, novolin, ReliOn): onset 2-4 hours, duration 10-16 hours, cloudy in appearance
- long-acting (lantus, levemir): onset 2-4 hours, duration 18-24 hours, start at 10 units/day or 0.1-0.2 units/kg, take around the same time every day
Complications
DAWN PHENOM: natural increase in the early morning blood glucose and insulin requirements due to increased glucose production in liver after overnight fast (increased need for insulin at dawn)
ACUTE HYPOGLYCEMIA: treat with glucose 15g CHO, wait 15 min
POSTPRANDIAL/REACTIVE HYPOGLYCEMIA: goal is to prevent marked rise in bg that would stim more insulin, avoid simple sugars, 5-6 meals/day, protein at RDA levels
Thyroid disorders
Hyperthyroidism: excess secretion of thyroid hormone, elevated T3 and T4, increased BMR, increase kcal
Hypothyroidism: deficiency of thyroid hormone, T4 low, T3 low or normal, decreased BMR leading to wt gain
Urea cycle defects
Unable to synthesize urea from ammonia resulting in ammonia accumulation,
diet-protein restriction (1.0, 1.5, 2g/kg based on tolerance, age, projected growth rate)
Phenylketonuria (PKU)
missing enzyme phenylalanine hydroxylase which would convert phenylalanine to tyrosine
Restrict phenylalanine, supplement the product tyrosine (tyrosine becomes essential)
Low protein, high CHO intakes may lead to incr. dental caries
Glycogen storage disease
Deficiency of glucose-6-phosphatase in liver, impairs gluconeogenesis and glycogenolysis
Provide a consistent supply of exogenous glucose with raw cornstarch at intervals, and a high carb, low fat diet
Homocystinurias
treatable inherited disorder of amino acid metabolism
newly diagnosed patients receive increased doses of folate, pyridoxine (B6), B12
Potentially low protein, low methionine diet