Nutrition Flashcards
Chemical name of Vitamin B1
Thiamine (active form thiamine pyrophosphate)
Chemical name of Vitamin B2
Riboflavin (precursor of FAD, FMN)
Chemical name of Vitamin B3
Niacin (precursor of NAD+)
Chemical name of Vitamin B5
Pantothenic Acid (precursor of acetyl CoA)
Chemical name of Vitamin B6
Pyrodoxine (active form pyridoxal phosphate)
Chemical name of Vitamin B7
Biotin
Chemical name of Vitamin B12
Cobalamin
Beriberi is a deficiency of…
Vitamin B1 (Thiamine)
Enzymes that need thiamine pyrophosphate as a cofactor (4)
1) Branched-chain ketoacid dehydrogenase
2) alpha-ketoglutarate dehydrogenase (TCA)
3) Pyruvate dehydrogenase (glycolysis to TCA link)
4) Transketolase (pentose phosphate pathway)
Confusion, opthalmoplegia, ataxia, confabulation, personality change, memory loss (permanent). Damage to medial dorsal nucleus of thalamus, mammillary bodies. TPP deficiency
Wernicke-Korsakoff syndrome
Polyneuropathy, symmetrical muscle wasting. TPP deficiency
Dry beriberi
High-output cardiac failure (dilated cardiomyopathy), edema. TPP deficiency
Wet beriberi
Deficiency of Vitamin B2 causes what symptoms (two C’s)
Cheilosis (inflammation of lips, scaling and fissures at the corners of the mouth) and corneal vascularization
What step in the TCA cycle needs cofactors derived from a Vitamin B2 (Riboflavin)
Succinate dehydrogenase
Deficiency of Vitamin B3
Pellagra