Nutrition

Question 1

B1 deficiency

Answer 1

Wernicke encephalopathy- COAT

Korsakoff syndrome- RACK

Dry beriberi- polyneuropathy, muscle wasting

Wet beriberi- cardiac failure, edema

Deficient in - branched chain ketoacid dehydrogenase,
Alphaketoglutarate dehydrogenase,
Pyruvate dehydrogenase
Transketolase

Question 2

B2 deficiency

Answer 2

Cheliosis

Corneal vascularisation

Question 3

B3

Derived from?

Answer 3

-from tryptophan
Glossitis
Pellagra- diarrhoea,dementia,dermatitis , hyperpigmentation of sun exposed areas

**Hartnup disease- deficiency of tryptophan transporter in PCT OF Renal tubule leading to pellagra like symptoms

Question 4

B9 def

Answer 4

Megaloblastic anemia without neurological symptoms

Glossitis

Question 5

Drugs causing b9 def

Answer 5

Phenytoin
Methotrexate
Sulfonamides

Question 6

B12 def

Answer 6

Megaloblastic anemia with SCD

Question 7

VIT C function

Answer 7

Antioxidant

Iron absorption

Hydroxylation of proline and lysine in collagen synthesis(**). def- collagen synthesis defect

Necessary for beta hydroxylase which converts dopamine to NE

Question 8

B 1,2,3

Answer 8

Thiamine. TPP
Riboflavin FAD+
Niacin NAD+

Question 9

B 5,6,7

Answer 9

PANTOTHENIC ACID. CoA
Pyridoxin
Biotin

Question 10

B 9,10

Answer 10

Folate

Cobalamine

Question 11

B1 is cofactor in

Answer 11

Maple syrup

Question 12

Cofactor in transamination reactions

Answer 12

B6