Nulls

Question 1

PP1Pk

Answer 1

p: A4GALT mutation, makes anti-PP1Pk

Question 2

MNS

Answer 2

MkMk- M-N-S-s-U-Wr(a-b-), Ena-
Deletion of GPA and GPB

Question 3

Kidd

Answer 3

Jk01N-melanasian, silencing gene
Jk02N-Finish, silencing gene
In(JK)- Japanese, weak expression, adsorp/elute

Question 4

Kell

Answer 4

K0- homozygous mutation, no kell glycoprotein, Kx^s, Ku-,Km-
Kmod- weak antigen expression, Kxs

Question 5

Duffy

Answer 5

ACKR1 mutation frame shift to a stop codon, white people
GATA Fyb on tissues not RBCs, african americans

Question 6

RH

Answer 6

Amorphic- RHD/RHCE gene mutation
Regulator- RHAG mutation
RH29-Neg
Hr0- Rh 17, RHCE neg, D–

Question 7

Cromer

Answer 7

INAB= IFC-, Japanese, intestinal disorders (dra is receptor for e.coli)

Question 8

Dombrock

Answer 8

Gy(a-)= white people
Hy-= african americans
Jo(a-)= african americans

Question 9

Indian

Answer 9

In(lu)- SNP of KLF1, decrease CD44, ANJW-, also Lu(a-b-) (same KLF1 gene)

Question 10

Lutheran

Answer 10

in(Lu)- dominant inhibitor gene at another locus inhibits lutheran
LuLu- recessive lu gene mutation
X linked Lu mod- Gata changes, trace antigens

Question 11

Kn

Answer 11

Helgeson phenotype= Si-, Yk-, Kn(a-b-), absence of KCAM

Question 12

Co

Answer 12

Silencing gene, if Co3+Co4-=functional aquaporin, Co3-=non functional aquaporin

Question 13

ChRg

Answer 13

C4 deficiencies, Ch- meningitis, Rh-Lupus

Question 14

Gerbich

Answer 14

Yus= 2-3+4+
Gerbich= 2-3-4+
Leach=2-3-4-, K decreased, GYC and GYD absent

Question 15

MN

Answer 15

En(a-)= GYA absent