nucleic acids (DNA) Flashcards

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1
Q

DNA - function

A
  • important information-carrying molecules
  • holds genetic information
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2
Q

RNA - fuc

A
  • important information-carrying molecules
  • transfers genetic information from DNA to the ribosomes
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3
Q

ribosomes

A

they are formed from RNA and proteins

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4
Q

structure of DNA

A

2 strands joined together in anti-parallel held together by hydrogen bonds between specific complementary base pairs (A-T, C-G), twisting into a double helix structure

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5
Q

structure of RNA

A

single short RNA polynucleotide strand

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6
Q

nucleotide - structure

A
  1. a pentose sugar
  2. a nitrogenous base
  3. a phosphate group
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7
Q

nucleotides (BLANK) make DNA or RNA which are nucleic acids (BLANK)

A

nucleotides (monomers) make DNA or RNA which are nucleic acids (polymers)

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8
Q

how are DNA or RNA nucleotides joined together?

A

joined together by a condensation reaction forming a phosphodiester bond (sugar phosphate backbone)

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9
Q

DNA nucleotides

A
  1. deoxyribose
  2. a phosphate group
  3. one of the organic bases (adenine, cytosine, guanine, thymine)
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10
Q

RNA nucleotides

A
  1. ribose
  2. a phosphate group
  3. one of the organic bases (adenine, cytosine, guanine, uracil)
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11
Q

double stranded - DNA structure

A

both strands can act as templates for semi-conservative replication

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12
Q

weak hydrogen bonds between bases - DNA structure

A

can be unzipped for replication

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13
Q

complementary base pairing - DNA structure

A

accurate replication

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14
Q

many hydrogen bonds between bases - DNA structure

A

stable/ strong molecules

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15
Q

double helix with sugar phosphate backbone - DNA structure

A

protect bases/ H bonds

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16
Q

long molecule - DNA structure

A

stores lots of genetic information that codes for polypeptides

17
Q

double helix (coiled) - DNA structure

A

compact

18
Q

DNA replication

A

the semi-conservative replication of DNA ensures genetic continuity between generations of cells

19
Q

replication process

A
  1. the DNA unwinds, then DNA helicase breaks the hydrogen bonds between the complementary base pairs
  2. the double helix unwinds and separates the two strands of DNA
  3. new DNA nucleotides bind to exposed bases on the DNA template strand
  4. DNA polymerase catalyses the condensation reaction that joins adjacent nucleotides
20
Q

DNA helicase

A
  • unwinds the DNA double helix
  • ensuring the bases on both strands are exposed
21
Q

DNA polymerase

A

lining of nucleotides in the developing strands via condensation reactions forming the phosphodiester bonds

22
Q

semi-conservative DNA replication

A

DNA must be able to replicate exact copies of itself

23
Q

who suggested the idea of semi-conservative DNA replication?

A

Watson and Crick suggested the strands would separate and each produce a new helix

24
Q

who confirmed the idea of semi-conservative DNA replication?

A

confirmed by Meselson and Stahl, who grew E. coli bacteria with radioactive-labelled nitrogen