nucleic acids Flashcards
structure nucleotide
phosphate, deoxyribose + organic base ie thymine
condesnation reaction bonds them together
circle - pent- rectangle
DNA; structure
phosphate
deoxyribose
bases; ACGT
deoxyribose acid
RNA:
phosphate
ribose
ACGU (bases)
ribonucleic acids
too much nucleic acid =?
gout, crystals form at joints / extremities
DNA shape and bonding
diagram; s phosphate in different directions matching bases pair in middle.
pyrimidine on one side purine on other (bases)
h-bonds between bases
complementary base pairing
antiparallel chains twist - giving double helix
to make new copy of a DNA molecule
double helix is untwisted
h-bonds between bases break (unzip) exposing bases
free DNA nucleotides are h-bonded to exposed bases according to base pairing rules ( A-t, C-G)
covalent bonds are formed between phosphate of one nucleotide and suugar of other securing backbone
Dna copying is described as
semiconservative as consists of one conserved and one new strand
RNA is different to DNA how?
ribose sugar
base u replaces t (a-u)
polynucleotide is oftensingle stranded
3 forms of RNA exist
transcription
bases of DNA exposed & RNA nucleotides complimentary bond
convalent bonds form between sugar and phosphate to secure backbone
3 forms of RNA
messenger - complemenatry to one strand of DNA
robosomal - found in ribosomes
transfer - carries amino acids to ribosomes, where they are bonded together to form polypeptides
protein synthesis
sequences of bases on DNA make up codes for particular protein molecules - code for the sequence of amino acids in the protein
Sequence coding for a particular protein (gene) can be exposed by splitting h-bonds between bases
RNA nucleotides form a complimentary strand (mRNA)
mRNA peels away form the DNA & leaves nucleus through nucleus pore
mRNA attaches to ribosome
Then tRNA molecules bring aminio acids to the ribosome in the correct order, according oo base sequence on the mRNA
the amino acids are jioned by peptide bonds to give a protein with a speicifc primary structure ( this then gives rise to secondary and tertiary structure)
nucleotide =
monomers of nucleic acid