NTI DRUGS

Question 1

What drug in Aminoglycosides
Indication
TW
Monitor

Answer 1

Gentamicin and Tobramycin
Indication: Bacterial Infections
TW: GENTAMICIN: 5-10 mcg/ml
Tombramycin: 20-40mcg/ml
Monitor: Gentamicin Level

Question 2

LITHIUM
indicatiom
TW
Monitor

Answer 2

Indication: Bipolar disorder
TW: 0.6 to 1.2 mEq/L
Lithium level

Question 3

Levothyroxine

Answer 3

Hypothyrodism
0.4 to 4.0 mIU/L
Thyroid function (TSH LEVEL)

Question 4

WARFARIN

Answer 4

Thrombosis
2-3 INR
INR

Question 5

PHENYTOIN

Answer 5

Seizures
10-20 mg/L
PHENYTOIN LEVEL

Question 6

CLOZAPINE

Answer 6

Schizophrenia
350-600 ng/mL
WHITE BLOOD CELL COUNT AND ABSOLUTE NEUTROPHIL COUNT

Question 7

DIGOXIN

Answer 7

Atrial Fibrilation
4-10 mg/L
Digoxin Level Also check for Hypokalemia (Increases Toxicity)

Question 8

HEPARIN

Answer 8

Thrombosis
46-70 PPT
INR

Question 9

METHOTREXATE

Answer 9

Rheumatoid Arthritis
Under 1 micromol/L at 48 hrs
FBC, LFTs, U&Es

Question 10

THEOPHYLLINE

Answer 10

Asthma/COPD
10-20 mg/L
Theophylline Level

Question 11

VALPROATE

Answer 11

Seizures
50-100 mcg/mL
Serum Valproic acid level
Complete Blood Count
Hepatic Function Test

Question 12

PROCAINAMIDE

Answer 12

Hearth Arrythmia
4-10 mcg/mL
ECG monitoring (QRS Complex, QT Interval)
Blood Pressure

Question 13

Cyclosporine

Answer 13

Immunosuppressant
Therapeutic rand depends on clinical situation
Blood Cyclosporine Conc. + U&Es, LFTs, FBC

Question 14

QUINIDINE

Answer 14

Hearth Arrythmia
1-4mcg/ml
Serum Quinidine Levels, Blood Pressure, QRS duration, and QT INTERVAL

Question 15

CARBAMAZEPINE

Answer 15

Seizures
4-10 mg/L
Serum Levels

Question 16

PHENOBARBITAL

Answer 16

Seizures
10-40 mg/L
Serum Phenobarbital Conc.

Question 17

Tacrolimus

Answer 17

Immunosuppresant
5-15 mcg/L
Renal function
Hepatic Function
Serum electrolytes (Mg, Phos, K)
Glucose
Blood Pressure

Question 18

VANCOMYCIN

Answer 18

Bacterial Infections
20-40 mcg/mL
Monitor Vancomycin Level