NS Tx & Pharma

Question 1

List the classes of Antidepressants (5)

Answer 1

• SSRIs
• TCAs
• MAOIs
• Other (SNRIs, NRIs, NDRIs, NaSSAs)
• Augmenters (Li, Valproate, Carbamezapine, Atypical antipsychotics)

Question 2

What is the MoA of Antidepressants

Answer 2

Increase the ammt of NTs present in the synaptic cleft of neurons
- note: takes time (~wks) to achieve response develop ∴ may involve ↑ or ↓ reg of receptors/other proteins)

Question 3

Key Fts that define Psychotic Disorders (5)

Answer 3

• Delusions
• Hallucinations
• Disorganised thinking (speech)
• Grossly disorganised/abnormal motor behaviour (incl Catatonia)
• -ve Symptoms