Nov 17 Notes Flashcards
particulate radiation comes from?
Alpha, Beta Neutrons, Photons and electrons.
Electromagnetic radiation types?
Gamma, xrays, high energy uv light
Have mass can have charged particles:
Particulate radiation
Electromagnetic description
has no mass and travels in waves
LET stands for
Linear Energy Transfer
LET definition
Average amount of energy per unit length of track through object (keV/um)
RBE stands for
relative biological effectiveness
RBE definition
Varying types of LETS will produce varying biological effects
Particulate radiation is most likely to interact with DNA, this is called
Direct Hit/ Target Hit
Electromagnetic radiation is most likely going to interact with
Cytoplasm
Indirect hits cause
Radiolysis, hydrolysis, production of free radicals, hydroxyl radicals, H3O+OH-
Different effects ionizing radiation can have on the cells are
Somatic and genetic
Stochastic effects
Are random in nature, have late effects and are evident months to years later.
Somatic stochastic effects can casue
cancer/leukemia
Genetic Stochastic effects can cause
mutation and mental retardation
Nonstochastic
not random, early, immediate occurs in mins, hours, days.
Somatic genetic effects can cause
erythema (radiodermatitis), Hair loss (alopecia), Temp sterility, reduction of RBC’s